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Age-related loss of Notch3 underlies brain vascular contractility deficiencies, glymphatic dysfunction, and neurodegeneration in mice.
Romay, Milagros C; Knutsen, Russell H; Ma, Feiyang; Mompeón, Ana; Hernandez, Gloria E; Salvador, Jocelynda; Mirkov, Snezana; Batra, Ayush; Sullivan, David P; Procissi, Daniele; Buchanan, Samuel; Kronquist, Elise; Ferrante, Elisa A; Muller, William A; Walshon, Jordain; Steffens, Alicia; McCortney, Kathleen; Horbinski, Craig; Tournier-Lasserve, Elisabeth; Sonabend, Adam M; Sorond, Farzaneh A; Wang, Michael M; Boehm, Manfred; Kozel, Beth A; Iruela-Arispe, M Luisa.
Afiliação
  • Romay MC; Department of Cell and Development Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
  • Knutsen RH; National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland, USA.
  • Ma F; Department of Cell and Development Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
  • Mompeón A; Department of Cell and Development Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
  • Hernandez GE; Department of Cell and Development Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
  • Salvador J; Molecular Biology Institute, University of California, Los Angeles, Los Angeles, California, USA.
  • Mirkov S; Department of Cell and Development Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
  • Batra A; Department of Cell and Development Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
  • Sullivan DP; Department of Pathology.
  • Procissi D; Department of Neurology, and.
  • Buchanan S; Department of Pathology.
  • Kronquist E; Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
  • Ferrante EA; Department of Biomedical Engineering, Northwestern University, Evanston, Illinois, USA.
  • Muller WA; Department of Cell and Development Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
  • Walshon J; National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland, USA.
  • Steffens A; National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland, USA.
  • McCortney K; Laboratory of Cardiovascular Regenerative Medicine, NIH, Bethesda, Maryland, USA.
  • Horbinski C; Department of Pathology.
  • Tournier-Lasserve E; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
  • Sonabend AM; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
  • Sorond FA; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
  • Wang MM; Department of Pathology.
  • Boehm M; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
  • Kozel BA; Inserm NeuroDiderot, Université Paris Cité, Paris, France.
  • Iruela-Arispe ML; Service de Génétique Neurovasculaire, Assistance Publique-Hôpitaux de Paris, Hôpital Saint-Louis, Paris, France.
J Clin Invest ; 134(2)2024 Jan 16.
Article em En | MEDLINE | ID: mdl-38015629
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Demência Vascular / Receptor Notch3 Limite: Animals / Humans Idioma: En Revista: J Clin Invest Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Demência Vascular / Receptor Notch3 Limite: Animals / Humans Idioma: En Revista: J Clin Invest Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos