Exercise and health-related quality of life and work-related outcomes in primary care patients with anxiety disorders - A randomized controlled study.
J Affect Disord
; 360: 5-14, 2024 Sep 01.
Article
em En
| MEDLINE
| ID: mdl-38777273
ABSTRACT
BACKGROUND:
Exercise interventions show promise in the treatment of anxiety disorders, but effects on health-related quality of life (HR-QoL), work ability, and sick leave are little studied. We investigated these outcomes in a 12-week randomized controlled trial with a 1-year follow-up.METHODS:
Patients aged 18-65 (n = 222) with anxiety disorders from primary care centers in Gothenburg were randomized to a control group or one of two 12-week exercise intervention groups (low-intensity, [LI] and moderate/high-intensity, [HI]); 148 were evaluated at 12-weeks and 113 completed the 1-year follow-up. The EuroQol 5D (EQ5D; index and the visual analogue scale [VAS]), work ability score (WAS), presenteeism, and self-reported sick leave were assessed at baseline, 12 weeks, and 1 year. Improvements were defined by binary cut-offs for each scale. Binary logistic regression with odds ratios (OR) and 95 % confidence intervals (CI) were reported.RESULTS:
There were improved scores for EQ5D and WAS in the HI group compared to controls after 12 weeks (EQ5D index 4.74 [1.91-11.7], EQ5D-VAS 4.00, [1.65-9.72], WAS 3.41 [1.24-7.37]) and 1 year (EQ5D index 3.05 [1.05-8.81], EQ5D-VAS 3.20 [1.16-8.84], WAS 5.50 [1.85-16.3]). Post-hoc analysis showed higher ORs in participants on antidepressants (n = 75) (12-week EQ5D index OR 9.95 [2.85-34.8]) and significant improvements in EQ5D scores for both intervention groups after 1 year. There were no between-group differences for presenteeism or sick leave.LIMITATIONS:
Discontinuation was high, mostly early after randomization (n = 74), as is common for anxiety interventions.CONCLUSIONS:
HI Exercise improves HR-QoL and work ability in anxiety patients, especially when combined with antidepressants.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transtornos de Ansiedade
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Atenção Primária à Saúde
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Qualidade de Vida
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Licença Médica
/
Terapia por Exercício
Limite:
Adolescent
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Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
J Affect Disord
Ano de publicação:
2024
Tipo de documento:
Article