Nucleotide sequence of the oncogene encoding the p21 transforming protein of Kirsten murine sarcoma virus.
Science
; 217(4563): 937-9, 1982 Sep 03.
Article
em En
| MEDLINE
| ID: mdl-6287573
ABSTRACT
The transforming protein of Kirsten murine sarcoma virus (Ki-MuSV) is a virally encoded 21-kilodalton protein called p21 kis. The sequences encoding p21 kis were genetically localized to a 1.3-kilobase segment near the 5' end of the viral genome by assaying the capacity of a series of defined deletion mutants of molecularly cloned Ki-MuSV DNA to induce focal transformation of mouse cells. Nucleotide sequencing of a portion of this region has led to the identification of an open reading frame of 567 nucleotides coding for p21 kis protein.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Proteínas Virais
/
Vírus do Sarcoma Murino de Kirsten
/
Vírus do Sarcoma Murino
Limite:
Animals
Idioma:
En
Revista:
Science
Ano de publicação:
1982
Tipo de documento:
Article