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1.
Ir Med J ; 112(10): 1026, 2020 12 16.
Artigo em Inglês | MEDLINE | ID: mdl-32311247

RESUMO

Aim Rhabdomyosarcoma (RMS) is the most common malignant soft tissue tumour of childhood. We present the case of a late relapse of RMS to the leptomeninges after 15 years. Methods A 20 year old male presented with a 3 week history of headaches and nausea. He previously had RMS of his right ear diagnosed at age 5 years which was treated with concurrent chemoradiotherapy. An MRI Brain and Spine confirmed extensive leptomeningeal disease and CSF analysis confirmed the presence of recurrent embryonal RMS. Results He completed two cycles of cyclophosphamide and topotecan followed by 45Gy/25Fr of craniospinal radiotherapy. Conclusion Late relapses beyond five years can be seen in up to 9% of patients, however very late recurrences (>10 years) are exceedingly rare. Molecular based methods such as gene expression profiling can aid risk stratification and survivorship clinics may become increasingly useful in following patients with high risk features.


Assuntos
Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Quimiorradioterapia/métodos , Neoplasias da Orelha/terapia , Neoplasias Meníngeas/terapia , Recidiva Local de Neoplasia/terapia , Doenças Raras , Rabdomiossarcoma Embrionário/terapia , Adulto , Pré-Escolar , Ciclofosfamida/administração & dosagem , Humanos , Masculino , Dosagem Radioterapêutica , Fatores de Tempo , Topotecan/administração & dosagem , Resultado do Tratamento , Adulto Jovem
2.
Am J Infect Control ; 20(5): 275-7, 1992 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-1443759

RESUMO

Long-term care facilities have only recently begun to receive attention in the area of infection control. A training program was developed in Nebraska to help supply practitioners with knowledge and techniques designed specifically for the long-term care environment. This program's success led to its implementation in other regions. The regional extensions of the program were designed to operate with independent faculty but standardized course materials.


Assuntos
Infecção Hospitalar/prevenção & controle , Profissionais Controladores de Infecções/educação , Capacitação em Serviço/organização & administração , Instituições Residenciais , Currículo , Humanos , Nebraska , Desenvolvimento de Programas
3.
Sports Med ; 10(2): 122-31, 1990 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-2204098

RESUMO

Ice hockey is a fast-paced game involving both finesse and controlled aggression. Injuries are related to direct trauma (80%) and overuse (20%), with high puck velocities, aggressive stick use, and body checking (collisions) accounting for most of these. A participant can anticipate an injury after playing 7 to 100 hours of hockey, depending on his age, and most injuries are caused during the actual game rather than during practice. Although facial injuries are common, they are decreasing because of adequate use of helmets and masks. Conversely, cervical spine injuries are being reported more frequently. Injuries to the upper extremity include acromioclavicular joint dislocations, scaphoid fractures, and 'gamekeeper's thumb.' Injuries to the lower extremity predominantly involve soft tissue, with strains of the hip adductor, tears of the medial collateral ligament of the knee, and contusions of the thigh are common. Scientific studies have reduced injury by providing improved protective equipment, stricter rules and their enforcement, and effective training and conditioning.


Assuntos
Hóquei/lesões , Ferimentos e Lesões/epidemiologia , Traumatismos do Braço/epidemiologia , Traumatismos do Braço/prevenção & controle , Traumatismos Craniocerebrais/epidemiologia , Traumatismos Craniocerebrais/prevenção & controle , Fatores Epidemiológicos , Traumatismos Oculares/epidemiologia , Traumatismos Oculares/prevenção & controle , Humanos , Traumatismos da Perna/epidemiologia , Traumatismos da Perna/prevenção & controle , Equipamentos de Proteção , Ferimentos e Lesões/prevenção & controle
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