1.
Ophthalmologe
; 102(8): 812-4, 2005 Aug.
Artigo
em Alemão
| MEDLINE
| ID: mdl-15449096
Assuntos
Neoplasias Oculares/complicações , Neoplasias Oculares/diagnóstico , Leucemia Mieloide Aguda/complicações , Leucemia Mieloide Aguda/diagnóstico , Hemorragia Retiniana/complicações , Hemorragia Retiniana/diagnóstico , Transtornos da Visão/etiologia , Adulto , Diagnóstico Diferencial , Neoplasias Oculares/terapia , Feminino , Humanos , Leucemia Mieloide Aguda/terapia , Hemorragia Retiniana/terapia , Resultado do Tratamento , Transtornos da Visão/diagnóstico , Transtornos da Visão/terapia
2.
Pediatr Blood Cancer
; 46(2): 239-42, 2006 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16369922
RESUMO
Diffuse neonatal hemangiomatosis (DNH) is a rare, frequently fatal disorder characterized by multiple cutaneous and visceral hemangiomas. Complications include high-output cardiac failure, hemorrhage, hepatic failure, and consumption coagulopathy. We present two cases of neonates with DNH. We prescribed cyclophosphamide after failure of corticosteroids. Cyclophosphamide induced a fast regression of the lesions with no side effects in both infants. We were able to stop treatment after 3-4 courses of cyclophosphamide in both infants because of the excellent response. Cyclophosphamide seems to be a safe and effective treatment in patients suffering from life-threatening DNH unresponsive to corticosteroids.