1.
Advanced vulvar apocrine carcinoma expressing estrogen receptors that responds to tamoxifen therapy.
Future Oncol
; 8(9): 1199-203, 2012 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23030494
RESUMO
Primary vulvar carcinoma is rare and thought to arise from either anogenital mammary-like glands or native apocrine sweat glands. The diagnosis is predominantly based on tumor morphology with supportive evidence from immunohistochemical staining and exclusion of a primary breast carcinoma. The primary modality of treatment is surgery, while optimal managment of advanced disease is unclear. We present the case of a lady who had metastatic recurrent apocrine carcinoma expressing estrogen receptors, who had a complete response assessed by PET-CT scanning after 7 months of tamoxifen therapy. The report includes a discussion of the histological diagnosis and assessment of response to treatment by PET-CT scanning.