Status and Influencing Factors of Social Media Addiction in Chinese Medical Care Professionals: A Cross-Sectional Survey.

Background: In modern society, social media addiction (SMA) has become a serious problem in many countries, including China. Almost every medical care professional has their own social media account. They are also at risk for SMA, but no SMA studies in Chinese medical care professionals have been published. This study aims to investigate the status and influencing factors of SMA among Chinese medical care professionals. Methods: A cross-sectional study was conducted among 519 physicians and nurses from two randomly selected hospitals using a questionnaire that included the Social Networking Service Addiction Scale (SNSAS), Maslach's Burnout Inventory-General Survey (MBI-GS), the General Self-efficacy Scale (GSES), and eight demographic datasets. Results: This study's findings showed that most of the participants' (357,68.79%) scores reached 2.5 points (half of the highest possible score), indicating that SMA scores of Chinese medical care professionals were relatively high. Significant differences in SMA scores by age (p < 0.01), marital status (p < 0.01), professional title (p < 0.01), and working years (p < 0.01) were found. Income satisfaction (p < 0.01) and sleep quality (p < 0.05) were negatively correlated with SMA. The GSES score was not correlated with SMA (p = 0.377). Burnout significantly positively affected SMA (p < 0.01). Conclusion: Our study found that the SMA scores of Chinese medical care professionals were relatively high. To reduce the SMA level of the medical care population, we should first start with reducing burnout, enabling medical care professionals to achieve sufficient sleep, increasing medical staff income, and providing more opportunities for promotion.

Early versus delayed oral feeding after gastrectomy for gastric cancer: A systematic review and meta-analysis.

BACKGROUND: Early oral feeding has been shown to be safe and effective for most surgeries, while surgeons and nurses are still hesitant to implement it in gastric cancer patients who undergo gastrectomy. OBJECTIVES: This review aimed to investigate the safety and feasibility of early versus delayed oral feeding in gastric cancer patients after gastrectomy. DESIGN: A systematic review and meta-analysis of randomized controlled trials. DATA SOURCES: The literature search was performed in 7 databases from inception to March 7, 2021. REVIEW METHODS: Randomized controlled trials that compared the effects of early oral feeding and delayed oral feeding in gastric cancer patients who undergo gastrectomy were included. The primary outcome was hospital days, and secondary outcomes included hospital costs, postoperative complication rates, feeding intolerance rates, annal exhaust time, albumin levels and prealbumin levels. According to the presence of heterogeneity, fixed or random effect meta-analysis was applied. RESULTS: Nine trials involving 1087 gastric cancer patients who undergo gastrectomy were pooled in this systemic review and meta-analysis. The results showed that early oral feeding significantly decreased hospital days (mean difference = -1.50, 95% confidence interval = -1.91 to -1.10, P < 0.001) and hospital costs (mean difference = -4.21, 95% confidence interval = -5.00 to -3.42, P < 0.001) compared to delayed oral feeding, while the incidences of postoperative complications (risk ratio = 0.96, 95% confidence interval = 0.72 to 1.26, P = 0.76) and feeding intolerance (risk ratio = 0.95, 95% confidence interval = 0.79 to 1.15, P = 0.62) were comparable between the two groups. In comparison to delayed oral feeding, early oral feeding was associated with shorter annal exhaust time (mean difference = -0.61, 95% confidence interval = -0.81 to -0.40, P < 0.001) and higher levels of albumin (mean difference = 3.77, 95% confidence interval = 2.42 to 5.12, P < 0.001) and prealbumin (mean difference = 18.11, 95% confidence interval = 15.33 to 20.88, P < 0.001). Furthermore, the results of distal gastrectomy subgroup analysis indicated that hospital days were shorter in the early oral feeding group than in the delayed oral feeding group. CONCLUSIONS: For gastric cancer patients who undergo gastrectomy, early oral feeding was associated with shorter hospital days and lower hospital costs, but early oral feeding did not increase the incidences of postoperative complications or feeding intolerance. Moreover, early oral feeding also decreased the annal exhaust time but increased the levels of albumin and prealbumin.

Neuroprotective effects of anthocyanins and its major component cyanidin-3-O-glucoside (C3G) in the central nervous system: An outlined review.

Anthocyanins, a class of water soluble flavonoids extracted from plants like berries and soybean seed, have been shown to display obvious anti-oxidative, anti-inflammatory, and anti-apoptotic activities. They are recommended as a supplementation for prevention and/or treatment of disorders ranging from cardiovascular disease, metabolic syndrome, and cancer. In the central nervous system (CNS), anthocyanins and its major component cyanidin-3-O-glucoside (C3G) have been reported to produce preventive and/or therapeutic activities in a wide range of disorders, such as cerebral ischemia, Alzheimer's disease, Parkinson's disease, multiple sclerosis, and glioblastoma. Both anthocyanins and C3G can also affect some important processes in aging, including neuronal apoptosis and death as well as learning and memory impairment. Further, the anthocyanins and C3G have been shown to prevent neuro-toxicities induced by different toxic factors, such as lipopolysaccharide, hydrogen peroxide, ethanol, kainic acid, acrolein, glutamate, and scopolamine. Mechanistic studies have shown that inhibition of oxidative stress and neuroinflammation are two critical mechanisms by which anthocyanins and C3G produce protective effects in CNS disorder prevention and/or treatment. Other mechanisms, including suppression of c-Jun N-terminal kinase (JNK) activation, amelioration of cellular degeneration, activation of the brain-derived neurotrophic factor (BDNF) signaling, and restoration of Ca2+ and Zn2+ homeostasis, may also mediate the neuroprotective effects of anthocyanins and C3G. In this review, we summarize the pharmacological effects of anthocyanins and C3G in CNS disorders as well as their possible mechanisms, aiming to get a clear insight into the role of anthocyanins in the CNS.