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1.
Matern Child Health J ; 27(4): 575-581, 2023 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-36862261

RESUMO

PURPOSE: Prenatal care is important for positive outcomes for both mother and infant. The traditional one-on-one method remains the most common. This study aimed to compare perinatal outcomes of patients attending group prenatal care with traditional prenatal care. Most previously published comparisons did not match for parity, a key predictor of perinatal outcome. DESCRIPTION: We collected perinatal outcome data for 137 group prenatal care patients and 137 traditional prenatal care patients, matched for contemporaneous delivery and parity, who delivered at our small rural hospital during 2015-2016. We included key public health variables, including the initiation of breastfeeding, and smoking at the time of delivery. ASSESSMENT: There was no difference between the two groups for maternal age or infant ethnicity, induced or augmented labor, preterm deliveries, APGAR scores less than 7, low birth weight, NICU admissions, or cesarean deliveries. Group care patients had more prenatal visits and were more likely to initiate breastfeeding and were less likely to report smoking at the time of delivery. CONCLUSION: In our rural population matched for contemporaneous delivery and parity, we found no difference in traditional perinatal outcome measures and that group care was positively associated with the key public health variables of not smoking and initiating breastfeeding. If future studies in other populations have similar findings, it may be wise to provide group care more widely to rural populations.


Assuntos
Cuidado Pré-Natal , População Rural , Gravidez , Recém-Nascido , Lactente , Feminino , Humanos , Paridade , Resultado da Gravidez/epidemiologia , Idade Materna
2.
Matern Child Health J ; 26(4): 941-952, 2022 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-34982339

RESUMO

INTRODUCTION: Home visiting (HV) programs aim to promote child and family health through perinatal intervention. HV may benefit second children through improving subsequent pregnancy and birth outcomes. However, HV impacts on birth outcomes of second children have not been examined in a naturalistic setting. METHODS: Using data from Connecticut Nurturing Families Network (NFN) home visiting program of families enrolled from 2005 to 2015, we compared birth-related outcomes (birthweight, preterm birth, Cesarean section delivery, prenatal care utilization) of second children (n = 1758) to demographically similar propensity-score-matched families that were not enrolled in NFN (n = 5200). We examined whether the effects of NFN differed by maternal age, race and ethnicity, or visit attendance pattern. RESULTS: There was no program effect for the full sample. The effect of NFN did not differ by maternal age or visit attendance pattern but did differ by maternal race and ethnicity. Black women in NFN were more likely to receive adequate prenatal care during their second pregnancy (OR 1.05; 95% CI 1.01, 1.09) and Hispanic women in NFN were less likely to deliver by Cesarean section for their second birth (OR 0.97; 95% CI 0.94, 0.99), compared to Black and Hispanic women in the comparison group respectively. There was a protective program effect on prematurity of the second child (OR 0.92; 95% CI 0.85, 0.996) for women with a preterm first birth. DISCUSSION: These findings suggest that benefits of HV extend to subsequent birth-related outcomes for women from marginalized racial/ethnic groups. HV may help buffer some harmful social determinants of health.


Assuntos
Cesárea , Nascimento Prematuro , Criança , Feminino , Humanos , Recém-Nascido , Idade Materna , Pais , Gravidez , Cuidado Pré-Natal
3.
Matern Child Health J ; 26(10): 2020-2029, 2022 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-35907127

RESUMO

OBJECTIVES: To assess whether a shorter length of stay (LOS) is associated with a higher risk of readmission among newborns with neonatal abstinence syndrome (NAS) and examine the risk, causes, and characteristics associated with readmissions among newborns with NAS, using a longitudinally linked population-based database. METHODS: Our study sample included full-term singletons with NAS (n = 4,547) and without NAS (n = 327,836), born in Massachusetts during 2011-2017. We used log-binomial regression models to estimate the crude risk ratios (cRRs) and adjusted RRs with 95% confidence intervals (CI) of the association between LOS and readmissions, controlling for maternal age, race/ethnicity, education, marital status, insurance, method of delivery, birthweight, adequacy of prenatal care, smoking, and abnormal conditions of newborn. RESULTS: Compared with infants without NAS, infants with NAS had a non-significantly higher risk of readmission within 2-42 days (2.8% vs. 2.5%; p = 0.17) and a significantly higher risk of readmission within 43-182 days (2.7% vs. 1.8%; p < 0.001). The risk of readmission within 2-42 days was significantly higher among infants with NAS with a LOS of 0-6 days compared to a LOS of 14-20 days (reference group) (aRR: 2.1; 95% CI: 1.2-3.5). No significant differences in readmission rates between 43 and 182 days were observed across LOS categories. CONCLUSIONS: Among infants with NAS, a LOS of 0-6 days was associated with a significantly higher risk of readmission within 2-42 days of discharge compared to a longer LOS.


Assuntos
Síndrome de Abstinência Neonatal , Feminino , Humanos , Lactente , Recém-Nascido , Tempo de Internação , Idade Materna , Síndrome de Abstinência Neonatal/epidemiologia , Alta do Paciente , Readmissão do Paciente , Gravidez
4.
JAMA ; 325(20): 2094-2109, 2021 05 25.
Artigo em Inglês | MEDLINE | ID: mdl-34032824

RESUMO

Importance: Counseling and active behavioral interventions to limit excess gestational weight gain (GWG) during pregnancy may improve health outcomes for women and infants. The 2009 National Academy of Medicine (NAM; formerly the Institute of Medicine) recommendations for healthy GWG vary according to prepregnancy weight category. Objective: To review and synthesize the evidence on benefits and harms of behavioral interventions to promote healthy weight gain during pregnancy to inform the US Preventive Services Task Force recommendation. Data Sources: Ovid MEDLINE and the Cochrane Library to March 2020, with surveillance through February 2021. Study Selection: Randomized clinical trials and nonrandomized controlled intervention studies focused on diet, exercise, and/or behavioral counseling interventions on GWG. Data Extraction and Synthesis: Independent data abstraction and study quality rating with dual review. Main Outcomes and Measures: Gestational weight-related outcomes; maternal and infant morbidity and mortality; harms. Results: Sixty-eight studies (N = 25 789) were included. Sixty-seven studies evaluated interventions during pregnancy, and 1 evaluated an intervention prior to pregnancy. GWG interventions were associated with reductions in risk of gestational diabetes (43 trials, n = 19 752; relative risk [RR], 0.87 [95% CI, 0.79 to 0.95]; absolute risk difference [ARD], -1.6%) and emergency cesarean delivery (14 trials, n = 7520; RR, 0.85 [95% CI, 0.74 to 0.96]; ARD, -2.4%). There was no significant association between GWG interventions and risk of gestational hypertension, cesarean delivery, or preeclampsia. GWG interventions were associated with decreased risk of macrosomia (25 trials, n = 13 990; RR, 0.77 [95% CI, 0.65 to 0.92]; ARD, -1.9%) and large for gestational age (26 trials, n = 13 000; RR, 0.89 [95% CI, 0.80 to 0.99]; ARD, -1.3%) but were not associated with preterm birth. Intervention participants experienced reduced weight gain across all prepregnancy weight categories (55 trials, n = 20 090; pooled mean difference, -1.02 kg [95% CI, -1.30 to -0.75]) and demonstrated lower likelihood of GWG in excess of NAM recommendations (39 trials, n = 14 271; RR, 0.83 [95% CI, 0.77 to 0.89]; ARD, -7.6%). GWG interventions were associated with reduced postpartum weight retention at 12 months (10 trials, n = 3957; mean difference, -0.63 kg [95% CI, -1.44 to -0.01]). Data on harms were limited. Conclusions and Relevance: Counseling and active behavioral interventions to limit GWG were associated with decreased risk of gestational diabetes, emergency cesarean delivery, macrosomia, and large for gestational age. GWG interventions were also associated with modest reductions in mean GWG and decreased likelihood of exceeding NAM recommendations for GWG.


Assuntos
Terapia Comportamental , Aconselhamento , Dieta , Exercício Físico , Ganho de Peso na Gestação , Complicações na Gravidez/prevenção & controle , Adolescente , Adulto , Cesárea , Diabetes Gestacional/prevenção & controle , Feminino , Macrossomia Fetal/prevenção & controle , Comportamentos Relacionados com a Saúde , Humanos , Hipertensão Induzida pela Gravidez/prevenção & controle , Recém-Nascido , Idade Materna , Obesidade/prevenção & controle , Obesidade/terapia , Gravidez
5.
BMC Pregnancy Childbirth ; 20(1): 702, 2020 Nov 17.
Artigo em Inglês | MEDLINE | ID: mdl-33203367

RESUMO

BACKGROUND: In the Twin Birth Study, women at 320/7-386/7 weeks of gestation, in whom the first twin was in cephalic presentation, were randomized to planned vaginal delivery or cesarean section. The study found no significant differences in neonatal or maternal outcomes in the two planned mode of delivery groups. We aimed to compare neonatal and maternal outcomes of twin gestations without spontaneous onset of labor, who underwent induction of labor or pre-labor cesarean section as the intervention of induction may affect outcomes. METHODS: In this secondary analysis of the Twin Birth Study we compared those who had an induction of labor with those who had a pre-labor cesarean section. The primary outcome was a composite of fetal or neonatal death or serious neonatal morbidity. Secondary outcome was a composite of maternal morbidity and mortality. TRIAL REGISTRATION: NCT00187369. RESULTS: Of the 2804 women included in the Twin Birth Study, a total of 1347 (48%) women required a delivery before a spontaneous onset of labor occurred: 568 (42%) in the planned vaginal delivery arm and 779 (58%) in the planned cesarean arm. Induction of labor was attempted in 409 (30%), and 938 (70%) had a pre-labor cesarean section. The rate of intrapartum cesarean section in the induction of labor group was 41.3%. The rate of the primary outcome was comparable between the pre-labor cesarean section group and induction of labor group (1.65% vs. 1.97%; p = 0.61; OR 0.83; 95% CI 0.43-1.62). The maternal composite outcome was found to be lower with pre-labor cesarean section compared to induction of labor (7.25% vs. 11.25%; p = 0.01; OR 0.61; 95% CI 0.41-0.91). CONCLUSION: In women with twin gestation between 320/7-386/7 weeks of gestation, induction of labor and pre-labor cesarean section have similar neonatal outcomes. Pre-labor cesarean section is associated with favorable maternal outcomes which differs from the overall Twin Birth Study results. These data may be used to better counsel women with twin gestation who are faced with the decision of interventional delivery.


Assuntos
Cesárea/estatística & dados numéricos , Doenças do Recém-Nascido/epidemiologia , Trabalho de Parto Induzido/estatística & dados numéricos , Complicações do Trabalho de Parto/prevenção & controle , Gravidez de Gêmeos/estatística & dados numéricos , Adulto , Índice de Apgar , Cesárea/efeitos adversos , Tomada de Decisão Clínica , Aconselhamento , Tomada de Decisão Compartilhada , Feminino , Idade Gestacional , Humanos , Recém-Nascido , Doenças do Recém-Nascido/etiologia , Doenças do Recém-Nascido/prevenção & controle , Trabalho de Parto Induzido/efeitos adversos , Idade Materna , Complicações do Trabalho de Parto/epidemiologia , Complicações do Trabalho de Parto/etiologia , Gravidez , Resultado do Tratamento , Adulto Jovem
6.
J Perinat Med ; 47(6): 656-664, 2019 Aug 27.
Artigo em Inglês | MEDLINE | ID: mdl-31211690

RESUMO

Objective To identify socio-cultural and clinician determinants in the decision-making process in the choice for trial of labor after cesarean (TOLAC) or elective repeat cesarean section (ERCS) in delivering women. Methods A tailored questionnaire focused on epidemiological, socio-cultural and obstetric data was administered to 133 patients; of these, 95 were admitted for assistance at birth at Fondazione Policlinico Universitario "A. Gemelli" (FPG) IRCCS, Rome, and 38 at S. Chiara Hospital (SCH), Trento, Italy. Descriptive analysis and logistic regression modeling were performed. Results Vaginal birth after cesarean (VBAC) rates were higher at SCH than at FPG (68.4% vs. 23.2%; P < 0.05). Maternal age in the TOLAC/VBAC group was significantly higher at SCH than at FPG (37.1 vs. 34.9 years, P < 0.05). High levels of education and no-working condition corresponded to a lower rate of VBAC. Proposal on delivery mode after a previous CS was missed in the majority of cases. Participation in prenatal course was significantly less among women in the ERCS groups. Using logistic regression, the following determinants were found to be statistically significant in the decision-making process: maternal age [odds ratio (OR) = 0.968 (95% confidence interval [CI] 0.941-0.999); P = 0.019], education level [OR = 0.618 (95% CI 0.419-0.995); P = 0.043], information received after the previous CS [OR = 0.401 (95% CI 0.195-1.252); P = 0.029], participation in antenatal courses [OR = 0.534 (95% CI 0.407-1.223); P = 0.045] and self-determination in attempting TOLAC [OR = 0.756 (95% CI 0.522-1.077); P = 0.037]. Conclusion In the attempt to promote person-centered care, increases in TOLAC/VBAC rates could be achieved by focusing on individual maternal needs. An ad hoc strategy for making birth safer should begin from accurate information at the time of the previous CS.


Assuntos
Recesariana , Cesárea , Prova de Trabalho de Parto , Nascimento Vaginal Após Cesárea , Adulto , Cesárea/psicologia , Cesárea/estatística & dados numéricos , Recesariana/psicologia , Recesariana/estatística & dados numéricos , Cultura , Tomada de Decisões , Feminino , Humanos , Itália/epidemiologia , Idade Materna , Anamnese/métodos , Preferência do Paciente , Assistência Centrada no Paciente/métodos , Assistência Centrada no Paciente/normas , Gravidez , Pesquisa Qualitativa , História Reprodutiva , Fatores Sociológicos , Nascimento Vaginal Após Cesárea/psicologia , Nascimento Vaginal Após Cesárea/estatística & dados numéricos
7.
Diabet Med ; 35(4): 519-529, 2018 04.
Artigo em Inglês | MEDLINE | ID: mdl-29338094

RESUMO

AIM: Women with gestational diabetes mellitus (GDM) are at increased risk of Type 2 diabetes. This study aimed to explore experiences, knowledge and perceptions of women with GDM to inform the design of interventions to prevent or delay Type 2 diabetes. METHODS: Semi-structured interviews were carried out with 16 women with GDM who were recruited from a clinic in one Scottish health board. A framework approach was used to manage and analyse data according to themes informed by psychological theory (self-regulation model and theory of planned behaviour). RESULTS: GDM is not seen as an important, or even real diagnosis among some women, and this perception may result from the perceived minimal impact of GDM on their lives. Some women did experience a bigger emotional and practical impact. Knowledge and understanding of Type 2 diabetes was poor in general and many women were unconcerned about their future risk. Lower concern appeared to be linked to a lower perceived impact of GDM. Lifestyle changes discussed by women mostly related to diet and were motivated primarily by concern for their baby's health. Many women did not maintain these changes postnatally, reporting significant barriers. CONCLUSIONS: This study has suggested potential avenues to be explored in terms of content, timing and potential recipients of interventions. Educational interventions postnatally could address illness perceptions in women with GDM and redress the situation where lack of aftercare downplays its seriousness. For lifestyle interventions, the child's health could be used as a motivator within the context of later joint or family interventions.


Assuntos
Diabetes Gestacional/psicologia , Conhecimentos, Atitudes e Prática em Saúde , Adulto , Ansiedade/etiologia , Compreensão , Diabetes Mellitus Tipo 2/prevenção & controle , Diabetes Mellitus Tipo 2/psicologia , Dieta , Exercício Físico/fisiologia , Exercício Físico/psicologia , Feminino , Culpa , Estilo de Vida Saudável , Humanos , Idade Materna , Pessoa de Meia-Idade , Paridade , Percepção , Cuidado Pós-Natal , Gravidez , Comportamento de Redução do Risco , Fatores Socioeconômicos , Adulto Jovem
8.
Br J Nutr ; 115(2): 285-93, 2016 Jan 28.
Artigo em Inglês | MEDLINE | ID: mdl-26571345

RESUMO

Fe deficiency remains the most common nutritional deficiency worldwide and young children are at particular risk. Preventative food-based strategies require knowledge of current intakes, sources of Fe, and factors associated with low Fe intakes; yet few data are available for Australian children under 2 years. This study's objectives were to determine intakes and food sources of Fe for Australian infants and toddlers and identify non-dietary factors associated with Fe intake. Dietary, anthropometric and socio-demographic data from the Melbourne Infant Feeding, Activity and Nutrition Trial Program were analysed for 485 infants (mean age: 9·1 (sd 1·2) months) and 423 toddlers (mean age: 19·6 (sd 2·6) months) and their mothers. Dietary intakes were assessed via 24-h recalls over 3 non-consecutive days. Prevalence of inadequate Fe intake was estimated using the full probability approach. Associations between potential non-dietary predictors (sex, breast-feeding status, age when introduced to solid foods, maternal age, maternal education, maternal employment status and mother's country of birth) and Fe intakes were assessed using linear regression. Mean Fe intakes were 9·1 (sd 4·3) mg/d for infants and 6·6 (sd 2·4) mg/d for toddlers. Our results showed that 32·6 % of infants and 18·6 % of toddlers had inadequate Fe intake. Main food sources of Fe were Fe-fortified infant formula and cereals for infants and toddlers, respectively. Female sex and current breast-feeding were negatively associated with infant Fe intakes. Introduction to solid foods at or later than 6 months was negatively associated with Fe intake in toddlers. These data may facilitate food-based interventions to improve Australian children's Fe intake levels.


Assuntos
Dieta , Alimentos Infantis , Fenômenos Fisiológicos da Nutrição do Lactente , Ferro da Dieta/administração & dosagem , Adulto , Austrália , Aleitamento Materno , Pré-Escolar , Grão Comestível , Escolaridade , Emprego , Feminino , Alimentos , Alimentos Fortificados , Comportamentos Relacionados com a Saúde , Humanos , Lactente , Fórmulas Infantis , Deficiências de Ferro , Masculino , Idade Materna , Pais , Fatores Sexuais
9.
Paediatr Perinat Epidemiol ; 30(2): 171-80, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-26739771

RESUMO

BACKGROUND: Perinatal characteristics may identify subgroups of term-born children at risk for academic and behavioural difficulties. Using follow-up data from the Pregnancy Outcomes and Community Health Study, we subdivided term births according to two potential markers of perinatal risk (gestational age, delivery circumstance) and evaluated their association with attention deficit hyperactivity disorder (ADHD) symptoms. METHODS: We included children born at term whose mothers completed the Conners' Parent Rating Scales-Revised-Short Form (CPRS-R-S) (n = 610; ages: 3-9 years). The CPRS-R-S yields age and sex-referenced T-scores for the two primary dimensions of ADHD (inattention, hyperactivity) and an ADHD Index that reflects both dimensions. Using general linear models, we evaluated whether: (1) term delivery defined by gestational week (reference: 39-40 weeks), or (2) term delivery circumstance defined by labour onset type and mode of delivery (reference: spontaneous labour, vaginal delivery) was associated with these problems. RESULTS: Following adjustment for parity, sociodemographics, and maternal mental health both during pregnancy and at the child follow-up survey, the induced labour plus caesarean group exhibited higher inattention and ADHD Index scores relative to the spontaneous labour, vaginal delivery group (inattention: mean difference = 5.1, 95% CI 0.6, 9.7; ADHD Index: mean difference = 4.1, 95% CI 0.5, 7.8). Findings were primarily driven by male children. CONCLUSIONS: Among term-born children, only those whose mothers experienced induction of labour that culminated in caesarean delivery exhibited higher levels of ADHD symptoms. Prenatal, antepartum, and/or postnatal factors associated with this delivery profile may reflect increased risk for such problems.


Assuntos
Transtorno do Deficit de Atenção com Hiperatividade/etiologia , Parto Obstétrico/estatística & dados numéricos , Idade Gestacional , Adulto , Cesárea/estatística & dados numéricos , Criança , Pré-Escolar , Feminino , Humanos , Trabalho de Parto Induzido/estatística & dados numéricos , Masculino , Idade Materna , Transtornos Mentais , Gravidez , Complicações na Gravidez , Adulto Jovem
11.
Hum Reprod ; 30(1): 16-9, 2015 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-25406182

RESUMO

Family planning visits are designed to help women build families in a manner most compatible with their life goals. Women's knowledge regarding age-related fertility is suboptimal, and first wanted pregnancies are now occurring at older ages. Here we review the issue of diminishing chances of a pregnancy occurring in women over 30 years of age. A debate arises over whether to perform a standard fertility assessment at an age when, for example, oocyte freezing is still practical and feasible, knowing that the proven predictors in subfertile couples may be less informative, or even inappropriate, in women without complaints about fertility. Studies have demonstrated that if women knew that their fertility was diminishing, they might alter life plans, including having children sooner or considering oocyte preservation. Therefore, we argue that physicians need to make an effort to evaluate a woman's childbearing priorities, though not necessarily their fertility, during the initial family planning visit.


Assuntos
Serviços de Planejamento Familiar , Fertilidade , Adulto , Fatores Etários , Feminino , Humanos , Infertilidade/prevenção & controle , Infertilidade/psicologia , Masculino , Idade Materna
12.
Pract Midwife ; 18(11): 16-20, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26753261

RESUMO

With a changing society, the age range at which women are choosing to become pregnant is increasing. There are different needs associated with each end of this range, with younger and older mothers facing different challenges and decisions. The midwife needs to be confident about the associated needs and potential complications for women at each end of the maternal age spectrum, in order to navigate the journey with the mother. This article aims to address the particular needs of both younger and older mothers, and highlight the midwife's unique role within this process


Assuntos
Idade Materna , Tocologia/organização & administração , Padrões de Prática em Enfermagem/organização & administração , Complicações na Gravidez/enfermagem , Cuidado Pré-Natal/organização & administração , Adulto , Feminino , Humanos , Papel do Profissional de Enfermagem , Gravidez , Complicações na Gravidez/prevenção & controle , Gestantes
13.
BMC Pregnancy Childbirth ; 14: 24, 2014 Jan 16.
Artigo em Inglês | MEDLINE | ID: mdl-24428902

RESUMO

BACKGROUND: Hemorrhage is the leading cause of maternal mortality in Bangladesh, the majority of which is due to postpartum hemorrhage (PPH), blood loss of 500 mL or more. Many deaths due to PPH occur at home where approximately 77% of births take place. This paper aims to determine whether the attendant at home delivery (i.e. traditional birth attendant (TBA) trained on PPH interventions, TBA not trained on interventions, or lay attendant) is associated with the use of interventions to prevent PPH at home births. METHODS: Data come from operations research to determine the safety, feasibility, and acceptability of scaling-up community-based provision of misoprostol and an absorbent delivery mat in rural Bangladesh. Analyses were done using data from antenatal care (ANC) cards of women who delivered at home without a skilled attendant (N =66,489). Multivariate logistic regression was used to assess the likelihood of using the interventions. RESULTS: Overall, 67% of women who delivered at home without a skilled provider used misoprostol and the delivery mat (the interventions). Women who delivered at home and had a trained TBA present had 2.72 (95% confidence interval, 2.15-3.43) times the odds of using the interventions compared to those who had a lay person present. With each additional ANC visit (maximum of 4) a woman attended, the odds of using the interventions increased 2.76 times (95% confidence interval, 2.71-2.81). Other sociodemographic variables positively associated with use of the interventions were age, secondary or higher education, and having had a previous birth. CONCLUSION: Findings indicate that trained TBAs can have a significant impact on utilization of interventions to prevent PPH in home births. ANC visits can be an important point of contact for knowledge transfer and message reinforcement about PPH prevention.


Assuntos
Parto Domiciliar , Tocologia/educação , Misoprostol/uso terapêutico , Ocitócicos/uso terapêutico , Hemorragia Pós-Parto/prevenção & controle , Absorventes Higiênicos , Adolescente , Adulto , Bangladesh , Escolaridade , Feminino , Parto Domiciliar/enfermagem , Assistência Domiciliar , Humanos , Idade Materna , Pessoa de Meia-Idade , Paridade , Hemorragia Pós-Parto/diagnóstico , Cuidado Pré-Natal , Autoadministração , Adulto Jovem
14.
BMC Pediatr ; 14: 280, 2014 Nov 07.
Artigo em Inglês | MEDLINE | ID: mdl-25380718

RESUMO

BACKGROUND: One of the most effective ways to promote the prevention of mother-to-child transmission (PMTCT) of HIV-1 in resource-limited settings is to encourage HIV-positive mothers to practice exclusive breastfeeding (EBF) for the first 6 months post-partum while they receive antiretroviral therapy (ARV). Although EBF reduces mortality in this context, its practice has been low. We studied the rate of adherence to EBF and assessed associated maternal and infant characteristics using data from a phase II PMTCT clinical trial conducted in Western Kenya which included a counseling intervention to encourage EBF by all participants. METHODS: We analyzed data from the Kisumu Breastfeeding Study (KiBS), conducted between July 2003 and February 2009. This study enrolled a total of 522 HIV-1 infected pregnant women. Data on breastfeeding were available for 480 mother-infant pairs. Infant feeding and general nutrition counseling began at 35 weeks gestation and continued throughout the 6 month post-partum intervention period, following World Health Organization (WHO) infant feeding guidelines. Data on infant feeding were collected during routine clinic visits and home visits using food frequency questionnaires and dietary recall methods. Participants were instructed to exclusively breastfeed until initiation of weaning at 5.5 months post-partum. We used Kaplan-Meier methods to estimate the rates of EBF at 5.25 months post-partum, stratified by maternal and infant characteristics measured at enrollment, delivery, and 2 weeks post-partum. RESULTS: The estimated EBF rate at 5.25 months post-partum was 80.4%. Only 3% of women introduced other foods (most commonly water with or without glucose, cow's milk, formula, and fruit) by 2 months; this percentage increased to 5% of women by 4 months. Women who had ≥3 previous births (p < 0.01) and who were not living with the infant's father (p = 0.04) were more likely to exclusively breastfeed. Mixed feeding was more common for male infants than for female infants (p = 0.04). CONCLUSION: Exclusive breastfeeding was common in this clinical trial, which emphasized EBF as a best practice until infants reached 5.5 months of age. Counseling initiated prior to delivery and continued during the post-partum period provided a consistent message reinforcing the benefits of EBF. The findings from this study suggest high adherence to EBF in resource limited settings can be achieved by a comprehensive counseling intervention that encourages EBF.


Assuntos
Terapia Antirretroviral de Alta Atividade , Aleitamento Materno , Infecções por HIV/tratamento farmacológico , HIV-1 , Transmissão Vertical de Doenças Infecciosas/prevenção & controle , Cooperação do Paciente , Assistência Perinatal , Complicações Infecciosas na Gravidez/tratamento farmacológico , Adulto , Aconselhamento , Feminino , Humanos , Recém-Nascido , Quênia , Masculino , Idade Materna , Paridade , Gravidez , Fatores Socioeconômicos , Adulto Jovem
15.
Anim Reprod Sci ; 263: 107456, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38503204

RESUMO

Successful reproduction is a cornerstone in food animal industry in order to sustain food production for human. Therefore, various methods focusing on genetics and postnatal environment have been identified and applied to improve fertility in livestock. Yet there is evidence indicating that environmental factors during prenatal and/or neonatal life can also impact the function of reproductive system and fertility in the animals during adulthood, which is called the developmental programming of reproduction. The current review summarizes data associated with the developmental origins of reproduction in the female animals. In this regard, this review focuses on the effect of plane of nutrition, maternal body condition, hypoxia, litter size, maternal age, parity, level of milk production and milk components, lactocrine signaling, stress, thermal stress, exposure to androgens, endocrine disrupting chemicals, mycotoxins and pollutants, affliction with infection and inflammation, and maternal gut microbiota during prenatal and neonatal periods on the neuroendocrine system, puberty, health of reproductive organs and fertility in the female offspring. It is noteworthy that these prenatal and neonatal factors do not always exert their effects on the reproductive performance of the female by compromising the development of organs directly related to reproductive function such as hypothalamus, pituitary, ovary, oviduct and uterus. Since they can impair the development of non-reproductive organs and systems modulating reproductive function as well (e.g., metabolic system and level of milk yield in dairy animals). Furthermore, when these factors affect the epigenetics of the offspring, their adverse effects will not be limited to one generation and can transfer transgenerationally. Hence, pinpointing the factors influencing developmental programming of reproduction and considering them in management of livestock operations could be a potential strategy to help improve fertility in food animals.


Assuntos
Fertilidade , Reprodução , Gravidez , Feminino , Humanos , Animais , Idade Materna , Ovário , Androgênios/farmacologia
16.
Crit Care Med ; 41(8): 1844-52, 2013 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-23648568

RESUMO

OBJECTIVE: To define the prevalence, indications, and temporal trends in obstetric-related ICU admissions. DESIGN: Descriptive analysis of utilization patterns. SETTING: All hospitals within the state of Maryland. PATIENTS: All antepartum, delivery, and postpartum patients who were hospitalized between 1999 and 2008. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: We identified 2,927 ICU admissions from 765,598 admissions for antepartum, delivery, or postpartum conditions using appropriate International Classification of Diseases, 9th Revision, Clinical Modification codes. The overall rate of ICU utilization was 419.1 per 100,000 deliveries, with rates of 162.5, 202.6, and 54.0 per 100,000 deliveries for the antepartum, delivery, and postpartum periods, respectively. The leading diagnoses associated with ICU admission were pregnancy-related hypertensive disease (present in 29.9% of admissions), hemorrhage (18.8%), cardiomyopathy or other cardiac disease (18.3%), genitourinary infection (11.5%), complications from ectopic pregnancies and abortions (10.3%), nongenitourinary infection (10.1%), sepsis (7.1%), cerebrovascular disease (5.8%), and pulmonary embolism (3.7%). We assessed for changes in the most common diagnoses in the ICU population over time and found rising rates of sepsis (10.1 per 100,000 deliveries to 16.6 per 100,000 deliveries, p = 0.003) and trauma (9.2 per 100,000 deliveries to 13.6 per 100,000 deliveries, p = 0.026) with decreasing rates of anesthetic complications (11.3 per 100,000 to 4.7 per 100,000, p = 0.006). The overall frequency of obstetric-related ICU admission and the rates for other indications remained relatively stable. CONCLUSIONS: Between 1999 and 2008, 419.1 per 100,000 deliveries in Maryland were complicated by ICU admission. Hospitals providing obstetric services should plan for appropriate critical care management and/or transfer of women with severe morbidities during pregnancy.


Assuntos
Unidades de Terapia Intensiva/estatística & dados numéricos , Admissão do Paciente/tendências , Complicações na Gravidez/epidemiologia , Transtornos Puerperais/epidemiologia , Aborto Induzido/estatística & dados numéricos , Adolescente , Adulto , Anestesia Obstétrica , População Negra/estatística & dados numéricos , Transtornos Cerebrovasculares/epidemiologia , Serviço Hospitalar de Emergência , Feminino , Cardiopatias/epidemiologia , Humanos , Infecções/epidemiologia , Tempo de Internação/estatística & dados numéricos , Falência Hepática/epidemiologia , Maryland/epidemiologia , Idade Materna , Medicaid/estatística & dados numéricos , Admissão do Paciente/estatística & dados numéricos , Transferência de Pacientes , Gravidez , Gravidez Ectópica/epidemiologia , Embolia Pulmonar/epidemiologia , Insuficiência Respiratória/epidemiologia , Estados Unidos , Ferimentos e Lesões/epidemiologia , Adulto Jovem
17.
Am J Trop Med Hyg ; 109(2): 277-283, 2023 08 02.
Artigo em Inglês | MEDLINE | ID: mdl-37364859

RESUMO

Young women in sub-Saharan Africa are a group at increased risk for malaria in pregnancy. Early antenatal care (ANC) seeking makes it more likely that women will receive the recommended doses of intermittent preventive treatment of malaria in pregnancy. This study used data from national Malaria Behavior Surveys conducted in Malawi and the Democratic Republic of the Congo (DRC) in 2021 to explore the association between intention to attend ANC in the first trimester for a future pregnancy (early ANC intention) and psychosocial factors among women aged 15-49 years. Eight psychosocial factors related to ANC and based on the ideation model were included, including knowledge, attitudes, and self-efficacy. The study used multivariable logistic regression models controlling for demographic characteristics to evaluate associations between early ANC intention and the individual ideational factors and the composite measure. Analysis included 2,148 women aged 15-49 years (Malawi: 827, DRC: 1,321). Antenatal care ideation was lower among young (aged 15-20 years) than among older (aged 21-49 years) women in Malawi. Young mothers with higher ANC ideation were more likely to intend to attend ANC early in their next pregnancy in both countries. Specific ideational factors associated with intention to attend ANC early varied by country and included positive attitudes, knowledge of ANC, and positive self-efficacy. In Malawi and the DRC, youth-friendly social and behavior change interventions to increase ANC-related ideation could increase future early ANC attendance among young women to improve malaria and birth outcomes.


Assuntos
Malária , Cuidado Pré-Natal , Adolescente , Gravidez , Feminino , Humanos , Idade Materna , República Democrática do Congo , Intenção , Malaui/epidemiologia , Malária/epidemiologia , Malária/prevenção & controle
18.
Paediatr Perinat Epidemiol ; 26(1): 13-8, 2012 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-22150703

RESUMO

Newborn care is of immense importance for the proper development and healthy life of a baby. Although child and infant mortality in South Asia has reduced substantially, the rate of neonatal mortality is still high, although these deaths can be prevented by adopting simple interventions at the community level. The aim of the study was to identify the associated factors which affect newborn care practices. Data for the study were drawn from the Bangladesh Demographic and Health Survey 2007, in which 6150 mothers were considered. The mean age of the mothers was 18 (±3.2) years. A little over 62% of the pregnant women received at least one antenatal check-up during the entire period of their pregnancy. About 70% of deliveries were conducted at home either by unskilled family members or by relatives. A clean instrument was used for cutting the cord of 87% of the newborn babies, while about 34% of them were reported to have had their first bath immediately after delivery. Initiation of breast feeding immediately after birth was practised in only about 19% of the cases. Compared with mothers with no education, those with secondary or higher levels were associated with clean cord care [odds ratio (OR) = 1.3, 95% confidence interval (CI) 1.0, 1.9] and early breast feeding [OR = 1.6, 95% CI 1.2, 2.2]. The study revealed an urgent need to educate mothers, and train traditional birth attendants and health workers on clean delivery practices and early neonatal care. Increasing the number of skilled birth attendants can be an effective strategy to increase safe delivery practices, and to reduce delivery complications.


Assuntos
Conhecimentos, Atitudes e Prática em Saúde , Cuidado do Lactente/métodos , Tocologia/métodos , Adolescente , Bangladesh/epidemiologia , Aleitamento Materno/estatística & dados numéricos , Parto Obstétrico , Países em Desenvolvimento , Feminino , Humanos , Cuidado do Lactente/normas , Recém-Nascido , Masculino , Idade Materna , Comportamento Materno/psicologia , Pessoa de Meia-Idade , Tocologia/normas , Assistência Perinatal/métodos , Assistência Perinatal/normas , Gravidez , Saúde da População Rural , Fatores Socioeconômicos , Saúde da População Urbana , Adulto Jovem
19.
BMC Pregnancy Childbirth ; 12: 73, 2012 Jul 28.
Artigo em Inglês | MEDLINE | ID: mdl-22838392

RESUMO

BACKGROUND: Mother-to-child transmission of HIV is a very important mode of HIV transmission for children. Well-functioning and accessible health facility and knowledge on mother to child transmission of HIV are a prerequisite for a successful mother to child transmission prevention of HIV. However, the determinant factors of pregnant mothers' knowledge towards mother to child transmission of HIV and its prevention is not well studied in Ethiopia and particularly in the present study area. METHODS: Cross-sectional health institution based study was conducted in Gondar town from July 22-August 18, 2011. A total of 400 pregnant women attending antenatal care (ANC) were involved in the study using stratified sampling technique. Data were collected by using structured questionnaire and multiple logistic regression analysis was used. RESULTS: A total of 400 pregnant women actively participated in this study and 354 (88.5%) of them knew mother to child transmission of HIV and 334(83.5%) of them knew mother to child transmission of HIV is preventable. Having knowledge on mother to child transmission of HIV was positively associated with attending antenatal care visits in hospitals [Adj. OR (95%CI) = 4.49 (1.003, 20.06)], residing in urban areas [Adj. OR (95%CI) = 2.46 (1.19, 5.09)] and having education level of secondary and above [Adj. OR (95%CI) = 6.85 (1.96, 24.01)], but negatively associated with increased maternal age. Knowledge on prevention of mother to child transmission of HIV was positively associated with accessibility of health facility [Adj. OR (95%CI) = 2.16 (1.03, 4.57)], having perceived risk of HIV [Adj. OR (95%CI) = 2.61 (1.32, 5.17)], having comprehensive knowledge on HIV [Adj. OR (95%CI) = 2.86 (1.41, 5.82)], having education level of secondary and above [Adj. OR (95%CI) = 6.15 (1.75, 21.66)] and residing in urban areas [Adj. OR (95%CI) = 3.62 (1.73, 7.59)] but negatively associated with increased maternal age. CONCLUSION: Most of the study participants in this study knew that HIV could be transmitted from an infected mother to her baby. There should be well functioning and accessible health facilities with Prevention of mother to child transmission service in the country especially in the rural areas.


Assuntos
Infecções por HIV/transmissão , Transmissão Vertical de Doenças Infecciosas , Adulto , Aleitamento Materno , Escolaridade , Etiópia , Feminino , Infecções por HIV/prevenção & controle , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Transmissão Vertical de Doenças Infecciosas/prevenção & controle , Masculino , Idade Materna , Gravidez , Adulto Jovem
20.
Eur J Public Health ; 22(6): 904-13, 2012 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-22109988

RESUMO

BACKGROUND: Prenatal healthcare is likely to prevent adverse outcomes, but an adequate review of utilization and its determinants is lacking. OBJECTIVE: To review systematically the evidence for the determinants of prenatal healthcare utilization in high-income countries. METHOD: Search of publications in EMBASE, CINAHL and PubMed (1992-2010). Studies that attempted to study determinants of prenatal healthcare utilization in high-income countries were included. Two reviewers independently assessed the eligibility and methodological quality of the studies. Only high-quality studies were included. Data on inadequate use (i.e. late initiation, low-use, inadequate use or non-use) were categorized as individual, contextual and health behaviour-related determinants. Due to the heterogeneity of the studies, a quantitative meta-analysis was not possible. RESULTS: Ultimately eight high-quality studies were included. Low maternal age, low educational level, non-marital status, ethnic minority, planned pattern of prenatal care, hospital type, unplanned place of delivery, uninsured status, high parity, no previous premature birth and late recognition of pregnancy were identified as individual determinants of inadequate use. Contextual determinants included living in distressed neighbourhoods. Living in neighbourhoods with higher rates of unemployment, single parent families, medium-average family incomes, low-educated residents, and women reporting Canadian Aboriginal status were associated with inadequate use or entering care after 6 months. Regarding health behaviour, inadequate use was more likely among women who smoked during pregnancy. CONCLUSION: Evidence for determinants of prenatal care utilization is limited. More studies are needed to ensure adequate prenatal care for pregnant women at risk.


Assuntos
Renda , Aceitação pelo Paciente de Cuidados de Saúde , Cuidado Pré-Natal/estatística & dados numéricos , Países Desenvolvidos , Feminino , Comportamentos Relacionados com a Saúde , Humanos , Idade Materna , Paridade , Gravidez , Características de Residência , Fatores Socioeconômicos , Fatores de Tempo
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