Questioning the 'neuroprotective' hypothesis: does drug treatment prevent brain damage in early psychosis or schizophrenia?
Br J Psychiatry
; 198(2): 85-7, 2011 Feb.
Article
em En
| MEDLINE
| ID: mdl-21282776
ABSTRACT
The idea that psychotic disorders are characterised by progressive neurodegeneration that can be reversed by drug treatment is used to justify early treatment of increasing numbers of mostly young people. I argue that there is little evidence to support the view that old- or new-generation antipsychotics are 'neuroprotective', and some evidence that the drugs themselves may be responsible for the decline in brain matter observed in some studies.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Transtornos Psicóticos
/
Antipsicóticos
/
Dano Encefálico Crônico
/
Fármacos Neuroprotetores
Limite:
Humans
Idioma:
En
Ano de publicação:
2011