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In vitro evaluation of the safety and efficacy of a high-power 450-nm semiconductor blue laser in the treatment of benign prostate hyperplasia.
Xu, Xiaofeng; Jiang, Dali; Liu, Guoxiong; Mu, Liyue; Zeng, Jin; Yang, Lin; He, Dalin.
Afiliação
  • Xu X; Department of Urology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China.
  • Jiang D; Department of Urology, Xianyang Central Hospital, Xianyang, 710061, Shaanxi, China.
  • Liu G; Department of Urology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China.
  • Mu L; Department of Urology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China.
  • Zeng J; Department of Urology, Xianyang Central Hospital, Xianyang, 710061, Shaanxi, China.
  • Yang L; Xi'an Lanji Medical Electronic Technology Co., Ltd., Xi'an, 710003, Shaanxi, China.
  • He D; Department of Urology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China.
Lasers Med Sci ; 37(1): 555-561, 2022 Feb.
Article em En | MEDLINE | ID: mdl-33770281
A 450-nm blue laser may be suitable to treat benign prostate hyperplasia (BPH) due to its haemoglobin absorption characteristic. The present study compared a novel high-power 450-nm semiconductor blue laser with other lasers marketed for in vitro soft tissue ablation, to evaluate the safety and efficacy of the 450-nm laser in BPH surgery. With the in vitro tissues on an experimental platform in water, the vaporization efficiency and coagulation layer thickness of the novel 450-nm laser and commercially available 532-nm, 980-nm, and 1470-nm lasers were measured at the same power (120 W). The damage to the adjacent tissue and the working noise were also measured. The vaporization efficiency was proved to be 450-nm laser > 532-nm laser > 1470-nm laser > 980-nm laser. Comparison of coagulation layer thickness was as follow: 980-nm laser > 1470-nm laser > 532-nm laser > 450-nm laser. The degree of tissue damage caused by the 450-nm and 532-nm lasers increased with the decrease in distance and increase in time (these are safe when a sufficient distance and short irradiation time are maintained). The heating ability of 980-nm and 1470-nm lasers was much greater than that of 450-nm and 532-nm lasers. The working noise was lower in 450-nm and 1470-nm lasers. The novel 450-nm laser has the advantages of highly efficient tissue vaporization, creating a thin coagulation layer, and low working noise. These characteristics suggest that the novel 450-nm laser may be a promising choice for the surgical treatment of BPH.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hiperplasia Prostática / Terapia a Laser Limite: Humans / Male Idioma: En Ano de publicação: 2022

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hiperplasia Prostática / Terapia a Laser Limite: Humans / Male Idioma: En Ano de publicação: 2022