Primer aislamiento en Argentina de Staphylococcus aureus resistente a la meticilina adquirido en la comunidad con sensibilidad intermedia a la vancomicina y no sensibilidad a la daptomicina. / [First isolation in Argentina of community-acquired methicillin-resistant Staphylococcus aureus with intermediate susceptibility to vancomycin and nonsusceptibility to daptomycin].
Errecalde Laura; Ceriana Paola; Gagetti Paula; Erbín Mariana; Duarte Andrea; J Rolón María; Cuatz Daniel; Corso Alejandra; Kaufman Sara.
Rev. Argent. Microbiol.
; 45(2): 99-103, 2013 Apr-Jun.
Artículo
en Español
| BINACIS | ID: bin-133054
UNLABELLED: We report the first case in Argentina of community-acquired methicillin-resistant Staphylococcus aureus with intermediate susceptibility to vancomycin and nonsusceptibility to daptomycin. CASE REPORT: A male patient with a history of chronic renal failure on hemodialysis and hip fracture osteosynthesis was admitted to hospital for persistent febrile syndrome following the displacement of the prosthesis by trauma. Blood cultures grew community-acquired methicillin-resistant Staphylococcus aureus. During treatment with vancomycin and daptomycin, a gradual increase in vancomycin MIC of 1 Ag/ml (VSSA) to 2 Ag/ml (h-VISA) and 4 Ag/ml (VISA) was observed, as well as the emergence of non-susceptibility to daptomycin (MIC = 4 Ag/ml). By suspending vancomycin and daptomycin, the strain reversed to the susceptible phenotype to both drugs. It is mandatory to evaluate by MIC the susceptibility to vancomycin and daptomycin during treatment when these drugs are used as therapy.
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