Asunto(s)
Carcinoma de Pulmón de Células no Pequeñas/diagnóstico , Carcinoma de Pulmón de Células no Pequeñas/terapia , Neoplasias Pulmonares/diagnóstico , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico , Carcinoma de Pulmón de Células no Pequeñas/epidemiología , Carcinoma de Pulmón de Células no Pequeñas/patología , Fumar Cigarrillos/efectos adversos , Terapia Combinada , Comorbilidad , Técnicas de Diagnóstico del Sistema Respiratorio , Humanos , Neoplasias Pulmonares/epidemiología , Neoplasias Pulmonares/patología , Neoplasias Pulmonares/terapia , Tamizaje Masivo , Estadificación de Neoplasias , Estrés Oxidativo , Neumonectomía/métodos , Enfermedad Pulmonar Obstructiva Crónica/epidemiología , Neumología , Radioterapia/métodos , Factores de Riesgo , Cese del Hábito de Fumar , Sociedades Médicas , España , Cirugía TorácicaRESUMEN
The Thoracic Surgery and Thoracic Oncology groups of the Spanish Society of Pulmonology and Thoracic Surgery (SEPAR) have backed the publication of a handbook on recommendations for the diagnosis and treatment of non-small cell lung cancer. Due to the high incidence and mortality of this disease, the best scientific evidence must be constantly updated and made available for consultation by healthcare professionals. To draw up these recommendations, we called on a wide-ranging group of experts from the different specialties, who have prepared a comprehensive review, divided into 4 main sections. The first addresses disease prevention and screening, including risk factors, the role of smoking cessation, and screening programs for early diagnosis. The second section analyzes clinical presentation, imaging studies, and surgical risk, including cardiological risk and the evaluation of respiratory function. The third section addresses cytohistological confirmation and staging studies, and scrutinizes the TNM and histological classifications, non-invasive and minimally invasive sampling methods, and surgical techniques for diagnosis and staging. The fourth and final section looks at different therapeutic aspects, such as the role of surgery, chemotherapy, radiation therapy, a multidisciplinary approach according to disease stage, and other specifically targeted treatments, concluding with recommendations on the follow-up of lung cancer patients and surgical and endoscopic palliative interventions in advanced stages.
Asunto(s)
Carcinoma de Pulmón de Células no Pequeñas/diagnóstico , Carcinoma de Pulmón de Células no Pequeñas/terapia , Neoplasias Pulmonares/diagnóstico , Neoplasias Pulmonares/terapia , Biomarcadores de Tumor/sangre , Broncoscopía , Carcinoma de Pulmón de Células no Pequeñas/prevención & control , Quimioradioterapia , Técnicas de Diagnóstico del Sistema Respiratorio/normas , Detección Precoz del Cáncer , Humanos , Neoplasias Pulmonares/prevención & control , Estadificación de Neoplasias , Cuidados Paliativos , Neumonectomía/normas , Tomografía Computarizada por Tomografía de Emisión de Positrones , Neumología/organización & administración , Terapia Recuperativa , Cese del Hábito de Fumar , Sociedades Médicas , España , Tomografía Computarizada por Rayos XRESUMEN
Treatment of lung carcinoma is multidisciplinary. There are different therapeutic strategies available, although surgery shows the best results in those patients with lung carcinoma in early stages. Other options such as stereotactic radiation therapy are relegated to patients with small tumors and poor cardiopulmonary reserve or to those who reject surgery. Adjuvant chemotherapy is not justified in patients with stage i of the disease and so double adjuvant chemotherapy should be considered. This adjuvant chemotherapy should be based on cisplatin after surgery in those patients with stages ii and IIIA.
