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1.
Clin Oncol (R Coll Radiol) ; 34(8): e355-e364, 2022 08.
Artículo en Inglés | MEDLINE | ID: mdl-35595594

RESUMEN

AIMS: The British Oncology Network for Undergraduate Societies (BONUS) surveyed students who attended an oncology revision day to determine their views on the current quantity, quality and type of curriculum-based oncology teaching they have experienced. MATERIALS AND METHODS: Students attending two BONUS revision days received a questionnaire assessing their experience of oncology teaching within the medical curriculum and interest in pursuing a future career in oncology using a 10-point Likert scale. Data were collected with informed consent to be anonymised and used for research. Student demographics and qualitative and quantitative data about experiences of oncology education were analysed. RESULTS: In total, 451 students registered to attend the revision days. After removal of duplicates, non-responders and non-UK participants, responses from 153 students studying across years 1-6 at 22 UK medical schools were analysed. The mean quantity of oncology lectures students reported receiving was 8.9 hours and the mean quantity of clinic/ward-based oncology teaching was 7.5 hours. Ninety (62.1%) of the 145 students who responded to the relevant question reported that they had received dedicated teaching in oncology. Students who had received dedicated oncology teaching reported a statistically significantly higher mean quality 6.1 (95% confidence interval 5.6-6.5) versus 5.0 (95% confidence interval 4.3-5.5; P = 0.003) and quantity 5.2 (95% confidence interval 4.7-5.6) versus 4.3 (95% confidence interval 3.7-4.9; P = 0.03) of oncology teaching compared with those who had not received this. CONCLUSION: Appropriate oncology education is essential for all medical students due to the high prevalence of cancer. All future doctors need the appropriate knowledge and communication skills to care for cancer patients. Our analysis provides quantitative evidence to support the value of specialist oncology teaching within the medical school curriculum in improving student-reported experience. National student-led revision days and events may widen interest in a future career in oncology and aid collaboration between oncology societies. It is important for the general undergraduate medical curriculum to integrate specialty content. An integrated curriculum should facilitate a holistic approach that spans prevention, screening, treatment and palliation rather than being split by subspeciality.


Asunto(s)
Educación de Pregrado en Medicina , Estudiantes de Medicina , Curriculum , Humanos , Oncología Médica , Reino Unido
2.
Mutat Res ; 564(1): 89-95, 2004 Nov 14.
Artículo en Inglés | MEDLINE | ID: mdl-15474415

RESUMEN

The effect of extracts from leaves of Myrtus communis on the SOS reponse induced by Aflatoxin B1 (AFB1) and Nifuroxazide was investigated in a bacterial assay system, i.e. the SOS chromotest with Escherichia coli PQ37. Aqueous extract, the total flavonoids oligomer fraction (TOF), hexane, chloroform, ethyl acetate and methanol extracts and essential oil obtained from M. communis significantly decreased the SOS response induced by AFB1 (10 microg/assay) and Nifuroxazide (20 microg/assay). Ethyl acetate and methanol extracts showed the strongest inhibition of the induction of the SOS response by the indirectly genotoxic AFB1. The methanol and aqueous extracts exhibited the highest level of protection towards the SOS-induced response by the directly genotoxic Nifuroxazide. In addition to anti-genotoxic activity, the aqueous extract, the TOF, and the ethyl acetate and methanol extracts showed an important free-radical scavenging activity towards the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical. These results suggest the future utilization of these extracts as additives in chemoprevention studies.


Asunto(s)
Antimutagênicos/farmacología , Radicales Libres/metabolismo , Myrtus/química , Extractos Vegetales/farmacología , Aflatoxina B1/farmacología , Antiinfecciosos/farmacología , Antimutagênicos/química , Antimutagênicos/metabolismo , Compuestos de Bifenilo/metabolismo , Escherichia coli/efectos de los fármacos , Escherichia coli/genética , Depuradores de Radicales Libres/metabolismo , Hidrazinas/metabolismo , Hidroxibenzoatos/farmacología , Pruebas de Mutagenicidad , Myrtus/anatomía & histología , Nitrofuranos/farmacología , Picratos , Extractos Vegetales/química , Extractos Vegetales/metabolismo , Hojas de la Planta/química , Respuesta SOS en Genética
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