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1.
Psicol. teor. prát ; 25(3): 15352, 10 jul. 2023.
Artículo en Inglés | LILACS | ID: biblio-1451199

RESUMEN

Risk perception is a concept related to the decision-making process and allows people to perceive the hazards surrounding the context and choose the best preventive methods to avoid them. The COVID-19 pandemic was a remarkable era in which people had to adopt protective methods, such as social isolation, to reduce the possibility of being contaminated by the virus. This study covers the development, psychometric properties, and norms of a scale to assess Risk Perception regarding COVID-19 and Social Isolation. The analysis suggested good expert agreement regarding the adequacy of the scale content and items and factor analysis suggested two factors, called the emotional and cognitive domains. The composite reliability suggested the internal consistency of the scale and its factors. All the results of this study suggest that this scale presents evidence of construct validity, constituting a reliable instrument. This new instrument may be used to evaluate risk perception related to COVID-19 and Social Isolation.


La percepción del riesgo es un concepto relacionado con el proceso de toma de decisiones y permite a las personas percibir los peligros en el contexto y elegir los mejores métodos de prevención para evitarlos. La pandemia de COVID-19 es una era notable en la que las personas deben adoptar métodos, como el aislamiento social, para reducir la posibilidad de ser contaminados por el virus. Este estudio proporciona el desarrollo, las propiedades psicométricas y las normas de una escala para evaluar Percepción de Riesgo sobre el COVID-19 y el Aislamiento Social. El análisis sugirió un buen acuerdo de expertos sobre el ajuste del contenido y la escala de ítems y el análisis factorial apuntó dos factores denominados dominios emocional y cognitivo. La confiabilidad compuesta sugirió consistencia interna de la escala y sus factores. Todos los resultados de este estudio proponen que esta escala presenta evidencia de validez de constructo y es un instrumento confiable. Este nuevo instrumento podrá ser utilizado para evaluar la percepción de riesgo sobre el COVID-19 y el aislamiento social.


A percepção de risco é um conceito relacionado ao processo de tomada de decisão e permite que as pessoas percebam os perigos em torno do contexto e escolham os melhores métodos de prevenção para evitá-los. A pandemia do COVID-19 é uma era marcante em que as pessoas devem adotar métodos de proteção, como o isolamento social, para reduzir a possibilidade de serem contaminados pelo vírus. Este estudo fornece o desenvolvimento, as propriedades psicométricas e normas de uma escala para avaliar Percepção de Risco sobre COVID-19 e Isolamento Social. A análise sugeriu boa concordância dos especialistas sobre o ajuste de conteúdo e itens da escala, e a análise fatorial sugeriu dois fatores denominados domínios emocionais e cognitivos. A confiabilidade composta sugeriu a consistência interna da escala e seus fatores. Todos os resultados deste estudo sugerem que esta escala apresenta evidências de validade de construto, sendo um instrumento confiável. Este novo instrumento poderá ser utilizado para avaliar a percepção de risco sobre a COVID-19 e o Isolamento Social.


Asunto(s)
Humanos , Masculino , Femenino , Adolescente , Adulto , Persona de Mediana Edad , Anciano , Adulto Joven , Psicometría/normas , Aislamiento Social/psicología , Encuestas y Cuestionarios/normas , COVID-19/psicología , Reproducibilidad de los Resultados , Análisis Factorial , Medición de Riesgo , COVID-19/virología
2.
Aval. psicol ; 21(2): 227-235, abr.-jun. 2022. ilus, tab
Artículo en Inglés | LILACS, INDEXPSI | ID: biblio-1447467

RESUMEN

The Neuropsychological Test for the Assessment of Visuospatial Binding (TNABV) was developed to measure the Working Memory binding for object-location features. This study aimed to provide validity evidence related to the content and internal structure of the TNABV. To investigate the evidence based on internal structure, the sample was composed of 1173 people. Participants were between 18 and 95 years of age. In order to investigate the content-related validity evidence, a judgment was performed through the analysis of seven experts. The data analysis was carried out through exploratory factor analysis, the Internal Consistency Content Validity Index (CVI). The result suggested a one-dimensional model with an explained variation of 41.78% and Cronbach's alpha of .82. The total CVI showed an agreement of .98. The findings indicated that the psychometric properties evaluated in the TNABV are adequate.(AU)


O Teste Neuropsicológico para Avaliação do Binding Visuoespacial (TNABV) foi desenvolvido para avaliar o binding da memória operacional para os recursos de objeto-localização. Este estudo investigou as evidências de validade relacionadas ao conteúdo e estrutura interna do TNABV. Para realizar as evidências baseadas na estrutura interna, a amostra foi composta por 1173 pessoas. Os participantes tinham entre 18 e 95 anos. Para investigar a validade das evidências baseadas no conteúdo, foi realizado um julgamento pela análise de sete especialistas. A análise dos dados foi realizada por meio de análise fatorial exploratória, Índice de Confiabilidade e Validade de Conteúdo (IVC). O resultado sugeriu um modelo unidimensional com uma variação explicada de 41,78% e o alfa de Cronbach de 0,82. O IVC total mostrou uma concordância de 0,98. Os achados indicaram que as propriedades psicométricas avaliadas no TNABV são adequadas.(AU)


El Test Neuropsicológico para la Evaluación de Binding Visuoespacial (TNABV) se desarrolló para evaluar el binding de la memoria operativa para los recursos de objeto-localización. Este estudio investigó las evidencias de validez relacionadas con el contenido y la estructura interna del TNABV. Para explorar las evidencias basadas en la estructura interna, la muestra se compuso por 1173 personas. Los participantes tenían entre 18 y 95 años. Para investigar la validez de las evidencias basadas en el contenido se realizó un juicio mediante la revisión de siete expertos. El análisis de los datos se ejecutó utilizando el análisis factorial exploratorio, el Índice de Confiabilidad y la Validez de Contenido (CVI). El resultado sugirió un modelo unidimensional con una variación explicada del 41,78% y un alfa de Cronbach de 0.82. El CVI total mostró una concordancia de 0,98. Los hallazgos indicaron que las propiedades psicométricas evaluadas en el TNABV son adecuadas.(AU)


Asunto(s)
Humanos , Masculino , Femenino , Adolescente , Adulto , Persona de Mediana Edad , Anciano , Anciano de 80 o más Años , Adulto Joven , Memoria a Corto Plazo , Pruebas Neuropsicológicas , Psicometría , Reproducibilidad de los Resultados , Análisis Factorial
3.
Environ Res ; 210: 112940, 2022 07.
Artículo en Inglés | MEDLINE | ID: mdl-35182597

RESUMEN

Neuropsychological alterations have been identified in populations heavily exposed to metals with neurotoxic potential, such as manganese (Mn). This study examined the associations between Mn environmental exposure in school-aged children and executive functions, using structural equation modeling. Children, aged between 7 and 12 years (N = 181), were recruited from four elementary schools located in a region that is under the influence of atmospheric emissions from a ferro-manganese alloy plant in the municipality of Simões Filho, Bahia, Brazil. The following cognitive functions were evaluated: Intelligence, Inhibitory Control, Cognitive Flexibility, Verbal and Design Fluency, Verbal and Visual Working Memory and Attention. We performed structural equation modeling to identify the following executive functions latent variables: working memory, inhibitory control and cognitive flexibility. We further analyzed the relations between executive functions and Mn measured in hair (MnH) and toenails (MnTn) with linear mixed models, after controlling for co-variables. A positive effect at the individual level on working memory, inhibition control and cognitive flexibility was observed with MnTn after controlling for co-variables, but no association was found with MnH levels. However, children attending school most environmentally exposed to Mn emissions, which had the highest rate of Mn dust deposition, had the poorest scores on working memory. These findings suggest both benefits and risk of Mn on children's cognitive development.


Asunto(s)
Función Ejecutiva , Manganeso , Niño , Exposición a Riesgos Ambientales/efectos adversos , Exposición a Riesgos Ambientales/análisis , Humanos , Iones/análisis , Iones/farmacología , Manganeso/análisis , Manganeso/toxicidad , Memoria a Corto Plazo , Análisis Multinivel
4.
Psicol. teor. prát ; 23(2): 1-21, May-Aug. 2021. ilus, tab
Artículo en Inglés, Portugués | LILACS, INDEXPSI | ID: biblio-1287701

RESUMEN

This study aims to present evidence of validity of the Attentional Performance Test (APT). The search for evidence based on content, internal structure and reliability was carried out. The content's evidence was run with the expert judgement (n = 07; k = 0.84) and semantic analysis (n = 12, k = 0.77). Their results suggested an adequate agreement with the content of the assessment of sustained attention (S.A), verbal commands and the images of the instrument. An analysis of the factorial structure (n = 1086) resulted on 2 main factors, 4 dimensions and 12 measures (RMSR = 0.08). An analysis of internal consistency (n = 1086) of the APT showed adequate values (α > 70). This study indicated that the APT presents evidence for content, construct and reliability. The present results contribute to APT evidences to confirm it as an adequate psychometric instrument to assess attention.


Este estudo tem por objetivo apresentar evidências de validade do Teste do Desempenho Atencional (TDA). Buscaram-se evidências baseadas no conteúdo, na estrutura interna e na fidedignidade. As evidências de conteúdo foram realizadas por intermédio da análise de juízes (n = 7; k = 0,84) e análise semântica (n = 12, k = 0,77), cujos resultados sugeriram concordância adequada quanto ao conteúdo de avaliação da atenção sustentada, aos comandos verbais e às imagens utilizadas no instrumento. A análise da estrutura fatorial (n = 1.086) do instrumento resultou em dois fatores principais, quatro dimensões e 12 medidas (RMSR = 0,08). A análise da consistência interna (n = 1.086) do TDA apresentou valores adequados (α > 70). Em conjunto, os resultados deste estudo mostram que o TDA apresenta evidências suficientes para o conteúdo, o construto e a fidedignidade. Os atuais resultados contribuem para confirmar o TDA como instrumento psicométrico adequado para avaliação da atenção.


Este estudio tiene como objetivo presentar evidencia de validez para el Test de Desempeño Atencional (TDA). Se realizó la búsqueda de evidencia basada en contenido, estructura interna y fiabilidad. Las evidencias de contenido se realizaron a través del análisis de expertos (n = 7; k = 0,84) y análisis semántico (n = 12, k = 0,77) y sus resultados sugirieron una adecuada concordancia con el contenido de evaluación de la atención sostenida, los comandos verbales y las figuras del instrumento. El análisis de la estructura factorial (n = 1.086) del instrumento se manifestó por dos factores principales, cuatro dimensiones y 12 medidas (RMSR = 0,08). El análisis de consistencia interna (n = 1.086) del TDA arrojó valores adecuados (α > 70). Este estudio sugiere que el TDA presenta evidencia suficiente de contenido, constructo y fiabilidad. Los resultados confirman que el TDA es un instrumento psicométrico adecuado para evaluación de la atención.


Asunto(s)
Humanos , Masculino , Femenino , Atención , Reproducibilidad de los Resultados , Cognición , Psicología , Sociedades , Brasil , Análisis Factorial , Crecimiento y Desarrollo , Exactitud de los Datos
5.
J Viral Hepat ; 28(12): 1672-1682, 2021 12.
Artículo en Inglés | MEDLINE | ID: mdl-34320255

RESUMEN

Direct-acting antivirals (DAAs) have been approved in recent years to treat patients infected by the Hepatitis C virus (HCV). The DAAs treatment is well tolerated and increases sustained virological responses, but there is no consensus about the neuropsychological functioning related to the treatment. This systematic review aims to provide an overview of the recent findings exploring the cognitive effects of DAAs treatment in patients with HCV. After a systematic search on PubMed, Embase, Scopus and LILACS, studies that assessed neuropsychological data related to DAAs treatment were included. We found nine articles, considering the inclusion and exclusion criteria. Three other manuscripts were included after searching for the references listed in the previously mentioned articles. We observed methodological heterogeneity in terms of neuropsychological tests used, cognitive domain explored and the sample characteristic presented between the studies. Studies presented data from HCV subjects monoinfected with or without cirrhosis, advanced liver disease and post-transplant patients; and HCV subjects coinfected with human immunodeficiency virus (HIV). Most results from the 12 studies that explored the effect of DAAs treatment in HCV subjects' neurocognitive functioning demonstrated cognitive improvement following treatment. In general, HCV and HCV/HIV subjects improved processing speed, verbal fluency and verbal/visual episodic memory. The DAAs treatment is effective for neurocognitive functioning in HCV monoinfected and coinfected subjects, with or without advanced liver disease, since neuropsychological scores increased after treatment. Further studies, however, are needed to confirm these findings.


Asunto(s)
Coinfección , Infecciones por VIH , Hepatitis C Crónica , Hepatitis C , Antivirales/efectos adversos , Coinfección/tratamiento farmacológico , Infecciones por VIH/tratamiento farmacológico , Hepacivirus , Hepatitis C/complicaciones , Hepatitis C/tratamiento farmacológico , Hepatitis C Crónica/complicaciones , Hepatitis C Crónica/tratamiento farmacológico , Humanos , Respuesta Virológica Sostenida
6.
Psychiatry Res ; 303: 114058, 2021 09.
Artículo en Inglés | MEDLINE | ID: mdl-34153630

RESUMEN

The objective of this study is to evaluate cognition in patients using either ketamine or esketamine to treat TRD. We also evaluate if both ketamine and esketamine as one group influence cognition in patients with TRD. Fifty-four patients with TRD were infused with either ketamine or esketamine and were assessed at three time points: baseline, 24 h, and 7 days after infusion. We applied neuropsychological tests to evaluate executive functions, processing speed, short term memory, and auditory-verbal episodic memory. There is no cognitive difference between ketamine and esketamine, with the exception of one variable. When considered as one group, ketamine and esketamine do not impair cognition; on the contrary, they improve some neuropsychological functions such as visuospatial short-term memory, executive functions, processing speed, and several measures related to episodic verbal memory. Ketamine and esketamine do not present differing cognitive effects when used in antidepressant doses to treat TRD. Furthermore, they rapidly improve many cognitive aspects of patients with TRD at 24 h after the infusion and maintain these effects for at least 7 days.


Asunto(s)
Trastorno Depresivo Resistente al Tratamiento , Ketamina , Depresión , Trastorno Depresivo Resistente al Tratamiento/tratamiento farmacológico , Método Doble Ciego , Humanos
7.
J Adolesc Health ; 69(2): 211-218, 2021 08.
Artículo en Inglés | MEDLINE | ID: mdl-34092475

RESUMEN

PURPOSE: This study explores adolescent well-being during the first wave of the COVID-19 pandemic in two high-income countries from Europe and one middle-income country from South America. The aim is to investigate the correlates of different dimensions of subjective well-being in 10- to 16-year-olds from different cultural contexts. METHODS: An online, self-report questionnaire was completed by 1,613 adolescents in Luxembourg, Germany, and Brazil between May and July 2020. The outcome variables were measures of life satisfaction and emotional well-being during the COVID-19 pandemic. The study included a range of sociodemographic, interpersonal, and intrapersonal covariates. Data were analyzed using descriptive statistics and latent variable structural equational modeling. RESULTS: A two-factor model of subjective well-being, consisting of life satisfaction and emotional well-being latent constructs, fitted well with this sample data for Luxembourg, Germany, and Brazil. Results showed that gender, socioeconomic status, intrapersonal factors, quantity and type of schoolwork, and relationships with adults were important common predictors of individual differences in subjective well-being during COVID-19. Fear of illness emerged as the strongest correlate of emotional well-being across the three countries. CONCLUSIONS: This study indicates that girls and adolescents from low-income homes may be especially vulnerable to negative secondary impacts of COVID-19 that can affect mental health. It identified several common correlates of subjective well-being in adolescents from different cultural settings, including factors that may be changeable, such as the following: the way adults listen to adolescents, schoolwork during distant learning, and fear of illness. Findings can inform the development of quality interventions for promoting the well-being of adolescents during a global pandemic.


Asunto(s)
COVID-19 , Pandemias , Adolescente , Adulto , Brasil/epidemiología , Europa (Continente) , Femenino , Alemania/epidemiología , Humanos , Luxemburgo/epidemiología , SARS-CoV-2
8.
Cogn Behav Neurol ; 33(2): 103-112, 2020 06.
Artículo en Inglés | MEDLINE | ID: mdl-32496295

RESUMEN

BACKGROUND: Cognitive impairment is often identified in individuals with bipolar disorder and is associated with their functional impairment. However, there is controversy surrounding potential classification methods for impairment in cognitive measures. OBJECTIVE: To examine the proportion of cognitive measures indicating impairment of attention, processing speed, memory, visuoconstructional abilities, and executive functions in individuals with bipolar disorder type I (euthymic) and healthy controls, using a strict criterion for defining impairment. METHODS: We gave 43 individuals with bipolar disorder type I and 17 healthy controls a comprehensive clinical and neuropsychological assessment. All scores were standardized using means and standard deviations according to age. Impaired performance in all cognitive measures was determined using a distribution-based threshold of z=±1645. The effects of the sociodemographic and clinical variables on cognitive performance were examined using multiple stepwise backward regression analyses. RESULTS: Clinically significant cognitive impairment was observed more frequently in the bipolar disorder group, compared to controls, on all measures. From participant factors, we found that level of education and number of manic episodes predicted variation in more cognitive measure scores. DISCUSSION: The use of population-based norms to standardize cognitive measures, and a strict criterion to define cognitive impairment, in individuals with bipolar disorder type 1 and healthy controls resulted in a prevalence of impairment in cognitive domains' frequencies of deficits that fell within the ranges previously reported in meta-analyses. CONCLUSIONS: Clinically introducing population norms and a stringent cognitive impairment criterion can facilitate more accurate measures of cognitive impairment in individuals with bipolar disorder.


Asunto(s)
Trastorno Bipolar/complicaciones , Trastorno Bipolar/psicología , Disfunción Cognitiva/etiología , Pruebas Neuropsicológicas/normas , Adolescente , Adulto , Estudios de Casos y Controles , Femenino , Humanos , Masculino , Persona de Mediana Edad , Adulto Joven
9.
Neurotoxicology ; 79: 48-57, 2020 07.
Artículo en Inglés | MEDLINE | ID: mdl-32335201

RESUMEN

BACKGROUND: Studies with children exposed to methylmercury (MeHg) through fish consumption in the Brazilian Amazon region report that the high levels of hair Hg are associated with significant decreases in intelligence, memory, attention, and visuospatial processing. OBJECTIVE: To investigate the relationship between mercury exposure and neuropsychological functions in riverside communities of the Brazilian Amazon. METHOD: 263 participants aged 6 to 14 years old were assessed, from resettlement regions, near the Madeira river, Rondônia, Brazil. To assess the neuropsychological functions we used the following instruments: intelligence (WASI), working memory (Corsi Block-Tapping Task and Digit Span), verbal fluency (Word Generation - NEPSY II), inhibitory control (Inhibition Errors - NEPSY II), shifting (Trail Making Test) and manual motor dexterity (Grooved PegBoard Test). Socioeconomic status was obtained through household surveys. Total Hg levels were quantified hair samples (Total HgH) collected from the occipital region of the scalp and analyzed by Cold Vapor Atomic Absorption Spectrometry. RESULTS: The group in the upper quartile of Total HgH levels presented lower scores on the tasks that assessed estimated IQ, visuospatial working memory, semantic knowledge and phonological verbal fluency, when compared to the group in the lower quartile level. A regression analysis controlled for age, sex, and maternal education showed that for each increase of 10 µg/g of Total HgH, there was a decrease around half standard deviation in Verbal IQ, estimated IQ scores, semantic knowledge, phonological verbal fluency and for verbal and visuospatial working memory. CONCLUSIONS: High concentrations of Total Hg in hair were associated with a lower performance in neuropsychological functions tests. The results show that environmental exposure to Hg is associated to children and adolescents' lower neuropsychological performance in the riverine and resettled areas of the Brazilian Amazon region.


Asunto(s)
Conducta del Adolescente/efectos de los fármacos , Desarrollo del Adolescente/efectos de los fármacos , Conducta Infantil/efectos de los fármacos , Desarrollo Infantil/efectos de los fármacos , Cabello/química , Intoxicación del Sistema Nervioso por Mercurio/etiología , Mercurio/efectos adversos , Contaminantes Químicos del Agua/efectos adversos , Adolescente , Factores de Edad , Brasil , Niño , Estudios Transversales , Exposición a Riesgos Ambientales/efectos adversos , Femenino , Contaminación de Alimentos , Humanos , Masculino , Mercurio/análisis , Intoxicación del Sistema Nervioso por Mercurio/diagnóstico , Intoxicación del Sistema Nervioso por Mercurio/fisiopatología , Pruebas Neuropsicológicas , Medición de Riesgo , Factores de Riesgo , Alimentos Marinos/efectos adversos , Alimentos Marinos/análisis , Contaminantes Químicos del Agua/análisis
10.
Artículo en Inglés | MEDLINE | ID: mdl-30384464

RESUMEN

Studies have demonstrated that, for urban children, dust represents the main exposure to sources of metals like lead (Pb) and manganese (Mn). We aimed to investigate the exposure to these metals and their association with intellectual deficit in children living in an industrial region. This cross-sectional study recruited volunteers from four elementary schools in the town of Simões Filho, Brazil. We evaluated 225 school-aged children (7⁻12 years) for blood lead (PbB) and manganese hair (MnH) and toenails (MnTn) by graphite furnace atomic absorption spectrometry. Child and maternal IQs were estimated using the Wechsler Abbreviated Scale for Intelligence (WASI). Median and range PbB were 1.2 (0.3⁻15.6) µg/dL. MnH and MnTn medians (ranges) were 0.74 (0.16⁻8.79) µg/g and 0.85 (0.15⁻13.30) µg/g, respectively. After adjusting for maternal IQ, age and Mn exposure, child IQ drops by 8.6 points for a 10-fold increase in PbB levels. Moreover, an effect modification of Mn co-exposure was observed. In children with low MnTn, association between Pb and child IQ was not significant (ß = -6.780, p = 0.172). However, in those with high MnTn, the association was increased by 27.9% (ß = -8.70, p = 0.036). Low Pb exposure is associated with intellectual deficit in children, especially in those with high MnTn.


Asunto(s)
Polvo/análisis , Exposición a Riesgos Ambientales/efectos adversos , Inteligencia/fisiología , Plomo/efectos adversos , Manganeso/efectos adversos , Estudiantes/estadística & datos numéricos , Encefalopatías , Brasil , Niño , Estudios Transversales , Exposición a Riesgos Ambientales/análisis , Monitoreo del Ambiente , Femenino , Cabello/química , Humanos , Pruebas de Inteligencia , Plomo/sangre , Masculino , Manganeso/sangre , Intoxicación por Manganeso/epidemiología , Instalaciones Industriales y de Fabricación , Uñas/química , Instituciones Académicas , Población Urbana/estadística & datos numéricos
11.
Neurotoxicology ; 69: 253-259, 2018 12.
Artículo en Inglés | MEDLINE | ID: mdl-29432852

RESUMEN

Manganese (Mn) is an essential element, however high levels of Mn have been associated with lower neuropsychological performance and behavioral problems in children. We investigated the associations between hair Mn concentrations and neuropsychological and behavioral performances among children with long-term exposure to airborne Mn aged between 7 and 12 years. Neuropsychological performance included tests of: verbal memory, inhibitory control, cognitive flexibility, verbal fluency, and motor function. We used the Conners Abbreviated Rating Scale for teachers to assess students' behaviors of hyperactivity. Hair manganese (MnH) concentrations in children and exposure to airborne manganese from a ferro-manganese alloy plant were analyzed and correlated with tests scores. Multivariable linear models adjusting for potential confounders showed that elevated levels of MnH were associated with lower performance in verbal memory, as measured by the free recall after interference (ß = - 1.8; 95% CI: - 3.4, - 0.2), which indicates susceptibility to interference, and Delayed Effect (ß = -2.0; 95% CI: -3.7, - 0.2), representing a loss of information over time. Additionally, we found patterns of effect modification by sex in three subtests measuring verbal memory: the free recall after interference score, Interference Effect, and Delayed Effect (all at p < 0.10). Overall, the results suggest that long-term airborne Mn exposure may be associated with lower performance in verbal memory, and hyperactivity behaviors.


Asunto(s)
Función Ejecutiva/efectos de los fármacos , Hipercinesia/inducido químicamente , Hipercinesia/epidemiología , Manganeso/efectos adversos , Memoria/efectos de los fármacos , Aprendizaje Verbal/efectos de los fármacos , Brasil/epidemiología , Niño , Estudios Transversales , Exposición a Riesgos Ambientales , Función Ejecutiva/fisiología , Femenino , Humanos , Hipercinesia/diagnóstico , Masculino , Memoria/fisiología , Aprendizaje Verbal/fisiología
12.
Psico (Porto Alegre) ; 49(4): 365-374, 2018.
Artículo en Inglés | LILACS | ID: biblio-969660

RESUMEN

Working memory (WM) refers to ability to store and manipulate information for a period of time. There is evidence of a close relationship between WM and learning. The aim of this study was to investigate the relationship between WM, intelligence quotient (IQ) on school achievement. Individual neuropsychological assessment was conducted following a specific protocol. The study included 227 children aged 7 to 12 years (M=9.87, SD=1.34), of which 119 were females, from private and public schools in Salvador, Bahia, Brazil. The data analysis included descriptive and inferential statistics. Academic achievement was evaluated using the Academic Performance Test (TDE), with subtests in reading, writing and arithmetic. The components of WM were evaluated using backward and forward Digit Span tasks and the backward and forward Corsi block-tapping task. The estimated IQ was assessed using tasks vocabularies and block design of the Wechsler scales. The statistical tests used were linear regression analysis (stepwise) and Pearson correlation. The results showed that the best predictors of academic performance were Digit Span Forward, Corsi Block Backward and Digit Span Backward task. The hypothesis of non-multicollinearity was tested, and it was verified that the constructs were independent (VIF <10 and Tolerance >0.20). The variance in academic performance explained by WM model was ΔR=0.36. High and significant correlations were observed between the components of WM and the TDE. The WM score (Digit Span Backward + Corsi Block Backward) and the TDE were correlated (r=0.54**). These results indicate that WM is a good predictor of academic achievement than IQ and are consistent with other findings showing WM as a predictor of learning or the potential for learning. This result has important implications for education, particularly with respect to intervention.


Memória de trabalho (MT) refere-se a capacidade de armazenar e manipular informações por um período de tempo. Há evidências de uma estreita relação entre MT e aprendizado. O objetivo deste estudo foi investigar a relação entre MT, quociente de inteligência (QI) no desempenho acadêmico. A avaliação neuropsicológica individual foi realizada seguindo um protocolo específico. O estudo incluiu 227 crianças com idades entre 7 a 12 anos (M=9.87, SD=1.34), das quais 119 eram do sexo feminino, de escolas privadas e públicas em Salvador, Bahia, Brasil. A análise de dados incluiu estatística descritiva e inferencial. O desempenho acadêmico foi avaliado usando o Teste de Desempenho Escolar (TDE), com subtestes de leitura, escrita e aritmética. Os componentes da MT foram avaliados usando tarefas de Span de Digitos e direta e inversa e a tarefa de Blocos de Corsi versão direta e inversa. O IQ estimado foi avaliado usando as tarefas de vocabulário e cubos das escalas Wechsler. Os testes estatísticos utilizados foram análise de regressão linear (enter) e correlação de Pearson. Os resultados mostraram que os melhores preditores de desempenho escolar foram as tarefas Digitos span direto, invertido e Cubos de Corsi direto e inverso. A hipótese de não-multicolinearidade foi testada, e verificou-se que os construtos foram independentes (VIF <10 e tolerância> 0,20). A variância no desempenho acadêmico explicado pelo modelo WM foi ΔR=0,12. Correlações significativas foram observadas entre os componentes da MT e do TDE. O escore da MT (Dígito span do inverso + Corsi Block inverso) e o TDE foram correlacionados (r=0,28 **). Estes resultados indicam que a MT é um bom preditor de realização escolar do que o QI e são consistentes com outros achados mostrando MT como um preditor de aprendizagem ou o potencial de aprendizagem. Este resultado tem implicações importantes para a educação, particularmente no que diz respeito à intervenção.


La memoria de trabajo (WM) se refiere a la capacidad de almacenar y manipular información durante un período de tiempo, y existe evidencia de una relación cercana entre la memoria de trabajo y el aprendizaje. El objetivo de este estudio fue investigar la relación entre la memoria de trabajo, la inteligencia (IQ) y el rendimiento escolar. La evaluación individual se realizó siguiendo un protocolo específico. El logro escolar se evaluó mediante la prueba de Logro escolar (TDE), con subpruebas en lectura, escritura y aritmética. Los componentes de la memoria de trabajo se evaluaron utilizando versiones anteriores y posteriores de Digit Span y las pruebas de bloqueo de tapado de Corsi. El IQ estimado se evaluó mediante las subpruebas Vocabulary and Block Design de Wechsler Intelligence Scale for Children III. El estudio incluyó a 227 niños de 7 a 12 años (M=9.87, SD=1.34), de los cuales 119 eran mujeres, de escuelas privadas y públicas en Salvador, Bahía, Brasil. El análisis de los datos incluyó estadística descriptiva e inferencial. Las pruebas estadísticas utilizadas fueron el análisis de regresión lineal (enter) y la correlación de Pearson. Los resultados mostraron que los mejores predictores de Logros Escolares fueron el Digit Span hacia adelante, hacia atrás y Corsi bloquean las tareas hacia adelante y hacia atrás. Se probó la hipótesis de no multicolinealidad y se verificó que las construcciones eran independientes (VIF <10 y Tolerancia >0.20). La variación en el rendimiento académico explicada por el modelo de memoria de trabajo fue ΔR=0.12. Se observaron correlaciones significativas entre los componentes de la memoria de trabajo y el TDE. La puntuación de la memoria de trabajo (Digit Span Backward + Corsi Block Backward) y el TDE se correlacionaron (r=0.28 **). Estos resultados indican que la memoria de trabajo es un buen predictor del rendimiento escolar que el coeficiente intelectual y es consistente con otros hallazgos que muestran que la memoria de trabajo es un predictor del aprendizaje o el potencial de aprendizaje. Este resultado tiene implicaciones importantes para la educación, particularmente con respecto a la intervención.


Asunto(s)
Rendimiento Académico , Pruebas de Inteligencia , Memoria a Corto Plazo
13.
Estud. psicol. (Campinas) ; 33(2): 283-291, abr.-jun. 2016. tab
Artículo en Inglés | LILACS | ID: lil-779876

RESUMEN

Studies that investigate handedness are performed in order to relate hemispheric specialization and cognitive performance. The aim of study was compare the neuropsychological performance between right-handed and left-handed children with ages from five to six years who participated in the Brazilian study of standardization of the Developmental Neuropsychological Assessment. For analysis of socio-demographic characteristics, descriptive statistics were used. To compare the mean scores between the groups, normality was tested using Analysis of Variance (one-way Anova) and the Kruskal-Wallis test. When comparing right-handed and left-handed children with typical development, left-handed children presented poorer performance on the subtests involving Attention and Executive Functioning, Language, and Learning and Memory.


Pesquisas sobre preferência manual são realizadas com o intuito de relacionar a especialização hemisférica cerebral e o desempenho cognitivo. O objetivo deste estudo foi comparar o desempenho neuropsicológico entre crianças destras e canhotas de cinco e seis anos de idade, participantes da pesquisa de normatização brasileira da Developmental Neuropsychological Assessment. Para análise das características sociodemográficas utilizou-se estatística descritiva. Para comparação dos escores entre os grupos, foi testada a normalidade, feita a Análise de Variância (Anova one-way) e o teste Kruskal-Wallis. Ao comparar crianças destras e canhotas com desenvolvimento típico, as canhotas apresentaram pior desempenho em subtestes que envolvem Atenção e Funções Executivas, Linguagem e Aprendizado e Memória.


Asunto(s)
Humanos , Preescolar , Niño , Lateralidad Funcional , Aprendizaje , Memoria , Neuropsicología
14.
Temas psicol. (Online) ; 24(1): 77-96, mar. 2016. ilus, tab
Artículo en Portugués | LILACS | ID: lil-788653

RESUMEN

O Emotion Regulation Checklist (ERC) é um instrumento de heterorrelato que se propõe avaliar o nível de regulação emocional de crianças por meio de duas subescalas, a saber, Regulação Emocional (RE) e Labilidade/Negatividade Emocional (L/N). A RE estima a expressão das emoções, empatia e autoconsciência emocional e a L/N avalia falta de flexibilidade, desregulação de raiva e labilidade do humor. Objetivou-se traduzir, adaptar e investigar evidências de validade da versão brasileira do ERC. Conduziram-se dois estudos: Estudo I: Tradução e Adaptação do ERC para a cultura brasileira; Estudo II: Investigação de evidências de validade do ERC. Participaram da pesquisa 561 informantes (pais e professoras) de crianças com idades de 3 a 12 anos. Os pressupostos para análise fatorial exploratória foram adequados e a solução bifatorial (RE e L/N) foi a indicada explicando 57% da variância (L/N α = 0,77 e RE α = 0,73). A subescala L/N apresentou correlações positivas com medidas de comportamentos problemáticos e a subescala RE apresentou correlações positivas com medidas de habilidades sociais. Os resultados suportaram primeiras evidências de validade do ERC para a cultura brasileira.


The Emotion Regulation Checklist (ERC) is an instrument for the hetero-evaluation of the level of emotion regulation of children by means of two scales, Emotion Regulation (ER) and Emotional Lability/Negativity (L/N). ER assesses the expression of emotions, empathy, and emotional self-awareness, while L/N assesses the lack of flexibility, anger dysregulation, and mood lability. The aim of this study is to perform the translation and cross-cultural adaptation of the ERC and investigate evidence of the validity of its Brazilian version. Two studies are conducted: Study I - Translation and cross-cultural adaptation of ERC for use in Brazil; and Study II - Investigation of evidence of the validity of the ERC. The sample includes 561 informants (parents and teachers) on children aged 3-12 years old. The exploratory factor analysis (EFA) assumptions are adequate, and the two-factor solution (ER and L/N) is shown to be the most adequate, explaining 57% of the variance (L/N α = .77 and ER α = .73). Subscale L/N is positively correlated with measurements of behavioral problems, while subscale ER is positively correlated with measurements of social skills. The present study provides the first evidence of the validity of the ERC for use in the Brazilian context.


El Emotion Regulation Checklist (ERC) es un instrumento de heterorrelato que propone evaluar el nivel de regulación emocional por medio de dos sub-escalas, Regulación Emocional (RE) y Labilidad/Negatividad (LN). La RE mide la expresión de las emociones, empatía y autoconsciencia emocional y la L/N evalúa la ausencia de flexibilidad, desregulación de rabia y labilidad del humor. Se tuvo como objetivo traducir, adaptar e investigar evidencias de validad de la versión brasileña del ERC. Fueron realizados dos estudios: Estudio I: Traducción y Adaptación del ERC para la cultura brasileña; Estudio II: Investigación de evidencias de validad del ERC. Participaron en esta investigación 561 informantes (padres y profesores) de niños con edad de 3 a 12 años. Los presupuestos para el análisis factorial exploratorio fueron adecuados y la solución bifactorial (RE y L/N) fue la indicada explicando el 57% de la varianza (L/N α = .77 y RE α = .73). La sub-escala L/N presentó correlaciones positivas con medidas de comportamientos problemáticos y la sub-escala RE presentó correlaciones positivas con medidas de habilidades sociales. Los resultados dan soporte a las primeras evidencias de validad del ERC para la cultura brasileña.


Asunto(s)
Humanos , Masculino , Femenino , Niño , Adulto , Adaptación a Desastres , Cultura , Estudios de Validación como Asunto
15.
Braz J Psychiatry ; 37(3): 245-8, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-26376056

RESUMEN

OBJECTIVE: The Barratt Impulsiveness Scale (BIS-11) is a valid and reliable instrument, and one of the most often used tools to assess impulsivity. This study assesses the performance of a large sample of adults by using a version of BIS-11 adapted to Brazilian Portuguese. METHODS: We assessed 3,053 adults from eight Brazilian states. Internal consistencies and performance data were presented for two correction criteria of BIS-11: original and the two-factor score. RESULTS: The associations between age, sex, region, and education and the BIS-11 scores present very small effect sizes. Therefore, we provided a percentile rank parameter for the different BIS-11 subscores considering the whole sample. Given the internal consistency of the two correction systems, we found that only the two-factor system fulfills the psychometric criteria of Cronbach's alpha (cutoff value of at least 0.6). CONCLUSION: Our results support the use of the Brazilian adaptation of BIS-11 in different regions of the country as a measure of impulsivity. Since high impulsiveness is a characteristic of several dysfunctional behaviors, the establishment of normative parameters is of utmost relevance and should be extended to other age ranges and populations in future studies.


Asunto(s)
Conducta Impulsiva , Escalas de Valoración Psiquiátrica/normas , Autoinforme/normas , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Brasil , Comparación Transcultural , Características Culturales , Escolaridad , Análisis Factorial , Femenino , Humanos , Masculino , Persona de Mediana Edad , Psicometría/normas , Estándares de Referencia , Reproducibilidad de los Resultados , Adulto Joven
16.
Psico USF ; 20(1): 97-108, Jan-Apr/2015. tab
Artículo en Portugués | LILACS | ID: lil-744525

RESUMEN

O desenvolvimento de normas para categorias semânticas é necessário para a compreensão do modo como os indivíduos organizam o conhecimento na memória e para a construção de instrumentos de avaliação cognitiva. O objetivo do presente estudo é fornecer normas associativas de 20 categorias semânticas para adultos e idosos brasileiros. Participaram do estudo 236 pessoas, entre 40 e 88 anos, das cinco regiões brasileiras. Os participantes responderam a um questionário de dados sociodemográficos e a um questionário de itens para categorias semânticas, e foram solicitados a produzir os cinco primeiros exemplares de cada categoria apresentada. Os resultados foram agrupados e são apresentadas as normas das categorias (exemplares, tamanho da categoria, respostas corretas, em branco e erros), bem como as respostas de cada categoria que foram comuns a todas as regiões brasileiras...


The development of semantic category norms is necessary to assist in the understanding of how individuals organize knowledge in memory, and to the creation of cognitive assessment instruments. The aim of this study is to provide associative norms of 20 semantic categories for Brazilian adults and elderly. The study included 236 participants from 40 to 88 years of age from the five Brazilian regions. They answered a socio-demographic questionnaire and a semantic category questionnaire, in which they were asked to produce the first five items of each category. Results are presented in category norms (items, category set size, correct responses, no responses and errors), as well as the responses that were common to all Brazilian regions belonging to each category...


Es necesario el desarrollo de normas para categorías semánticas para poder comprender cómo las personas organizan el conocimiento en la memoria y para la construcción de instrumentos de evaluación cognitiva. El objetivo de este estudio es proporcionar normas asociativas de 20 categorías semánticas para muestras de brasileños adultos y ancianos. Participaron 236 personas entre 40 y 88 años, de cinco regiones de Brasil. Los participantes completaron un cuestionario de datos sociodemográfico y un cuestionario de ítems para categorías semánticas y se les solicitó la producción de los cinco primeros ejemplares de cada categoría presentada. Los resultados fueron agrupados y son presentadas las normas de las categorías (ejemplares, tamaño de categoría, respuestas correctas, en blanco y errores), así como las respuestas de cada categoría, comunes a todas las regiones de Brasil...


Asunto(s)
Humanos , Masculino , Femenino , Adulto , Persona de Mediana Edad , Anciano de 80 o más Años , Semántica , Pruebas de Asociación de Palabras/normas
17.
Psicol. teor. prát ; 17(1): 120-135, abr. 2015.
Artículo en Portugués | LILACS | ID: lil-747871

RESUMEN

O presente estudo teve por objetivo traçar o perfil do desempenho de escolares no domínio atenção/funções executivas e inteligência, além de comparar o desempenho de crianças de escola pública e particular, e analisar as relações entre as variáveis sociodemográficas. Participaram 60 escolares de 6 a 12 anos. Foram verificadas correlações significativas entre desempenho no Wisc III e no domínio de atenção/funções executivas da bateria Nepsy com as variáveis sexo, tipo de escola, renda familiar e escolaridade dos pais. Quando comparadas com as crianças de escola particular, as de escola pública obtiveram desempenho significativamente inferior em todos os testes avaliados. Compararam-se os resultados por tipo de escola com os dados de normatização norte-americana do Nepsy e percebeu-se que as crianças brasileiras de rede pública obtiveram resultado significativamente inferior apenas no subteste de atenção visual, ao passo que os estudantes de escolas particulares obtiveram melhores escores em atenção visual e auditiva, em tarefas de planejamento, seleção e alternância de estímulos.


The present study aimed to profile the performance of students in attention/executive functions and intelligence domains, compare the performance of children in public and private schools, and analyse the relation between sociodemographic varia­bles. Participants were 60 students aged 6 to 12 years old. Significant correlations were found between performance on the Wisc III and attention/executive functions domain (Nepsy batery) with the variables gender, school type, family income, parent education. Public school children had significantly lower performance in all tests assessed compared to private school children. The results was compared by type of school with the North American normative data of Nepsy and it was noticed that Brazilian public children had significantly lower result only in visual attention subtest, while students from private schools had better scores in visual and auditory attention, in planning tasks, selection and alternating stimuli.


Este estudio tuvo como objetivo hacer el perfil del rendimiento de los estudiantes en el dominio de atención/funciones ejecutivas y de inteligencia, además de comparar el desempeño de los niños de las escuelas públicas y privadas, y analizar la relación entre las variables sociodemográficas. Participaron 60 estudiantes de 6 a 12 años. Se encontraron correlaciones significativas entre el desempeño en el Wisc III y en el dominio de la atención/ funciones ejecutivas de la batería Nepsy con las variables sexo, tipo de escuela, el ingreso familiar, la educación de los padres. Los niños de las escuelas públicas obtuvieron rendimiento significativamente más bajo en todas las pruebas evaluadas en comparación a los niños de escuela privada. Los resultados fueron comparados por tipo de escuela con los datos normativos norteamericanos del Nepsy y se observó que el grupo de niños brasileños de las escuelas públicas obtuvieron resultados significativamente más bajos sólo en la prueba atención visual, mientras que los estudiantes de las escuelas privadas tuvieron mejores puntuaciones en la atención visual y auditiva, en las tareas de planificación, selección y estímulos alternados.


Asunto(s)
Niño , Neuropsicología
18.
Estud. psicol. (Natal) ; 19(4): 258-267, out.-dez. 2014. tab
Artículo en Portugués | LILACS | ID: lil-741500

RESUMEN

A Memória Operacional (MO) é um componente das funções executivas essenciais para o desenvolvimento cognitivo da criança. Ela tem efeitos sobre a aprendizagem e as tarefas diárias. O objetivo foi revisar a literatura para identificar as principais tarefas que foram utilizadas para avaliar a MO e a qualidade psicométrica. Foi realizada uma revisão da literatura em bancos de dados (Pubmed, Medline, Lilacs, SciELO). Foram analisados 44 artigos que utilizaram tarefas que avaliaram a alça fonológica e/ou esboço visuoespacial. A partir das análises dos artigos foram descritas um total de 20 diferentes tarefas para avaliar a MO. Com a revisão sistemática foi possível descrever diferentes tarefas a partir de um modelo cognitivo. No entanto, são necessários estudos psicométricos, para validação das medidas dentro do modelo teórico e o refinamento...


Working memory (WM) is an essential component of executive functions for the cognitive development of children. It has effects on learning and cognitive tasks daily. The objective was to review the literature to identify the key tasks that are being used to evaluate the WM and psychometric quality. A review of the literature databases (Pubmed, Medline, Lilacs, SciELO) was performed. Forty-four articles that presented tasks that assessed phonological and / loop or visuospatial sketch and described a total of 20 different task to assess WM were analyzed. It was possible to verify the existence of different tasks to assess WM. It is interesting to build different tasks from the model cognitive proposed. However, you must have theoretical foundation and psychometric studies for the proposed tasks...


La memoria de trabajo (MT) es un componente esencial de las funciones ejecutivas para el desarrollo cognitivo de los niños. Tiene efectos en las tareas de aprendizaje y de todos los días. El objetivo fue revisar la literatura para identificar las tareas clave que se utilizan para evaluar la calidad psicométrica y MT. Se realizó una revisión de las bases de datos bibliográficas (PubMed, Medline, Lilacs, SciELO). Cuarenta y cuatro artículos que utilizaron tareas que evaluaron fonológico y / o mango se analizaron boceto visuoespacial. A partir del análisis de los artículos se describieron un total de 20 tareas diferentes para evaluar la MT. Es interesante para construir diferentes tareas de un modelo cognitivo propuesto. Sin embargo, es necesario tener fundamento teórico y estudios psicométricos para las tareas propuestas...


Asunto(s)
Humanos , Adolescente , Ciencia Cognitiva , Pesos y Medidas , Memoria a Corto Plazo , Psicología , Psicometría
19.
Psico USF ; 19(2): 297-306, maio-ago. 2014. ilus, tab
Artículo en Portugués | LILACS | ID: lil-722210

RESUMEN

As emoções desempenham um papel central nas relações das crianças e déficits na compreensão de emoções têm sido associados a diversos transtornos neuropsiquiátricos na infância. Entretanto, verifica-se uma escassez de instrumentos psicológicos disponíveis no Brasil que avaliem esta habilidade. O presente estudo teve por objetivo adaptar transculturalmente o Teste de Conhecimento Emocional (EMT). O instrumento original foi traduzido por uma equipe de pesquisadores bilíngues e posteriormente retraduzido para o inglês. As versões preliminares foram julgadas pelos autores do instrumento e por juízes brasileiros especialistas. A versão final foi aplicada em uma amostra de 50 crianças entre três e seis anos de idade e respondida por nove juízes de três estados brasileiros. Os resultados mostram uma boa equivalência semântica, além de bons níveis de concordância quanto às respostas (κ= 0,88, Z=95,2, p<0,001). A versão final do EMT mostrou-se adequada e satisfatória...


Emotions play a central role in children's relationships. Deficits in emotional understanding have been associated with several neuropsychiatric disorders. In Brazil, however, few psychological instruments are available to assess young children's emotional development. The objective of the present study was to make a transcultural adaptation of the Emotion Matching Task (EMT). The EMT was translated and adapted by a team of bilingual researches and then back-translated to English. The preliminary versions were assessed by EMT's authors and by Brazilians specialized judges. The final version was applied in a sample of 50 children between three and six years of age and answered by nine judges in three Brazilian states. The results indicate good semantic equivalence and good agreement with the answers provided (κ= 0.88, Z=95.2, p<0.001). The final version of the EMT was considered appropriate and satisfactory...


Las emociones desempeñan un papel central en las relaciones y déficits en la comprensión de emociones ha sido asociado a diversos trastornos neurológicos y psiquiátricos en la infancia. Sin embargo, se verifica que en Brasil existen pocos instrumentos que evalúen esta habilidad. Este estudio tiene como objetivo adaptar transculturalmente el Test de Conocimiento Emocional (EMT). El instrumento original fue traducido al portugués por un equipo de investigadores bilingues y, posteriormente, retraducido al inglés. Las versiones preliminares fueron juzgadas por los autores del instrumento y por jueces brasileros especialistas. La versión final fue aplicada a una muestra de 50 niños entre tres y seis años de edad y respondida por nueve jueces de tres estados brasileros. Los resultados muestran una buena equivalencia semántica, además de buenos niveles de concordancia con las respuestas (k=0,88; Z=95,2; p<0,001). La versión final del EMT se mostró adecuada y satisfactoria...


Asunto(s)
Humanos , Masculino , Femenino , Preescolar , Niño , Adaptación a Desastres , Emociones , Pruebas Neuropsicológicas , Traducción
20.
Toxicol Lett ; 231(2): 169-78, 2014 Dec 01.
Artículo en Inglés | MEDLINE | ID: mdl-24992226

RESUMEN

Manganese (Mn), an essential element to humans, in excess can cause neurotoxic damage. So far, Mn exposure assessment has no ideal biomarker. This study aims to investigate the association between Mn exposure, using noninvasive biomarkers, and neuropsychological effects in environmentally exposed adults. The residents of two communities near to a ferromanganese refinery in Bahia, Brazil were evaluated. Volunteers aged 15-55 of both sexes provided scalp hair, axillary hair, fingernail and saliva specimens for Mn determination by electrothermal absorption spectrometry. Several neuropsychological tests were used to evaluate cognitive, attention, memory, motor and executive functions. Significant correlations were observed between Mn in hair (MnH, median 8.95 µg/g), axillary hair (MnAxH,18.49 µg/g) and fingernail (MnFN, 6.91 µg/g) with the performances in several neuropsychological tests. No association was observed between manganese levels in saliva (MnSal, 4.2 µg/L) and any neuropsychological function. Multiple regression analysis detected an inverse association between Log MnH and IQ (ß=-4.76 [CI 95% -9.17 to -0.36]) and between Log MnFN and visual working memory (ß=-3.33 [CI 95% -6.15 to -0.52]). Direct association was observed between Log MnFN and time of completion in the cognitive flexibility task (ß=56.29 [CI 95% 2.41-110.18]). The Mn biomonitoring using noninvasive biomarkers was able to detect high exposure levels, which were associated with detrimental neuropsychological effects in adults exposed to industrial emissions.


Asunto(s)
Exposición a Riesgos Ambientales , Contaminantes Ambientales/toxicidad , Manganeso/química , Manganeso/toxicidad , Pruebas Neuropsicológicas , Adolescente , Adulto , Biomarcadores , Brasil , Femenino , Cabello/química , Humanos , Masculino , Persona de Mediana Edad , Minería , Uñas/química , Saliva/química , Adulto Joven
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