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1.
Nat Commun ; 11(1): 1704, 2020 Apr 06.
Artículo en Inglés | MEDLINE | ID: mdl-32249777

RESUMEN

Antiferromagnetic thin films are currently generating considerable excitement for low dissipation magnonics and spintronics. However, while tuneable antiferromagnetic textures form the backbone of functional devices, they are virtually unknown at the submicron scale. Here we image a wide variety of antiferromagnetic spin textures in multiferroic BiFeO3 thin films that can be tuned by strain and manipulated by electric fields through room-temperature magnetoelectric coupling. Using piezoresponse force microscopy and scanning NV magnetometry in self-organized ferroelectric patterns of BiFeO3, we reveal how strain stabilizes different types of non-collinear antiferromagnetic states (bulk-like and exotic spin cycloids) as well as collinear antiferromagnetic textures. Beyond these local-scale observations, resonant elastic X-ray scattering confirms the existence of both types of spin cycloids. Finally, we show that electric-field control of the ferroelectric landscape induces transitions either between collinear and non-collinear states or between different cycloids, offering perspectives for the design of reconfigurable antiferromagnetic spin textures on demand.

2.
Nat Mater ; 19(4): 386-390, 2020 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-31685944

RESUMEN

Chirality, a foundational concept throughout science, may arise at ferromagnetic domain walls1 and in related objects such as skyrmions2. However, chiral textures should also exist in other types of ferroic materials, such as antiferromagnets, for which theory predicts that they should move faster for lower power3, and ferroelectrics, where they should be extremely small and possess unusual topologies4,5. Here, we report the concomitant observation of antiferromagnetic and electric chiral textures at domain walls in the room-temperature ferroelectric antiferromagnet BiFeO3. Combining reciprocal and real-space characterization techniques, we reveal the presence of periodic chiral antiferromagnetic objects along the domain walls as well as a priori energetically unfavourable chiral ferroelectric domain walls. We discuss the mechanisms underlying their formation and their relevance for electrically controlled topological oxide electronics and spintronics.

3.
Nat Mater ; 19(5): 576, 2020 May.
Artículo en Inglés | MEDLINE | ID: mdl-31719690

RESUMEN

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

4.
Nature ; 549(7671): 252-256, 2017 09 13.
Artículo en Inglés | MEDLINE | ID: mdl-28905889

RESUMEN

Although ferromagnets have many applications, their large magnetization and the resulting energy cost for switching magnetic moments bring into question their suitability for reliable low-power spintronic devices. Non-collinear antiferromagnetic systems do not suffer from this problem, and often have extra functionalities: non-collinear spin order may break space-inversion symmetry and thus allow electric-field control of magnetism, or may produce emergent spin-orbit effects that enable efficient spin-charge interconversion. To harness these traits for next-generation spintronics, the nanoscale control and imaging capabilities that are now routine for ferromagnets must be developed for antiferromagnetic systems. Here, using a non-invasive, scanning single-spin magnetometer based on a nitrogen-vacancy defect in diamond, we demonstrate real-space visualization of non-collinear antiferromagnetic order in a magnetic thin film at room temperature. We image the spin cycloid of a multiferroic bismuth ferrite (BiFeO3) thin film and extract a period of about 70 nanometres, consistent with values determined by macroscopic diffraction. In addition, we take advantage of the magnetoelectric coupling present in BiFeO3 to manipulate the cycloid propagation direction by an electric field. Besides highlighting the potential of nitrogen-vacancy magnetometry for imaging complex antiferromagnetic orders at the nanoscale, these results demonstrate how BiFeO3 can be used in the design of reconfigurable nanoscale spin textures.

5.
J Magn Reson ; 257: 94-101, 2015 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-26112328

RESUMEN

Here we describe a new high frequency/high field continuous wave and pulsed electrically detected magnetic resonance (CW EDMR and pEDMR) setup, operating at 263GHz and resonance fields between 0 and 12T. Spin dependent transport in illuminated hydrogenated amorphous silicon p-i-n solar cells at 5K and 90K was studied by in operando 263GHz CW and pEDMR alongside complementary X-band CW EDMR. Benefiting from the superior resolution at 263GHz, we were able to better resolve EDMR signals originating from spin dependent hopping and recombination processes. 5K EDMR spectra were found to be dominated by conduction and valence band tail states involved in spin dependent hopping, with additional contributions from triplet exciton states. 90K EDMR spectra could be assigned to spin pair recombination involving conduction band tail states and dangling bonds as the dominating spin dependent transport process, with additional contributions from valence band tail and triplet exciton states.

6.
East Mediterr Health J ; 17(12): 969-75, 2011 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-22355951

RESUMEN

This study aimed to develop growth centiles at different gestational weeks for fetal biparietal diameter, abdominal circumference, femur length and head circumference in a Pakistani cohort. Data were collected at a tertiary referral hospital from pregnant women at gestational ages 13-40 weeks referred for obstetric ultrasound as a part of routine antenatal care. A total of 1599 fetal sonographic biometric measurements were collected after screening for the inclusion criteria. For each measurement, separate regression models were derived to estimate the mean, standard deviation and reference percentiles at each week of gestational age for this cohort. The best fitting model for each variable was selected. These charts will help radiologists and clinicians in predicting dates of delivery, assessing fetal growth and identifying intrauterine fetal insufficiency in the Pakistani population.


Asunto(s)
Desarrollo Fetal , Gráficos de Crecimiento , Ultrasonografía Prenatal , Antropometría , Femenino , Edad Gestacional , Humanos , Pakistán , Embarazo , Análisis de Regresión
7.
J Pak Med Assoc ; 54(3): 123-7, 2004 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-15129870

RESUMEN

OBJECTIVE: To evaluate the role of biphasic contrast-enhanced helical CT including Hepatic Arterial Phase (HAP) imaging with Portal Venous Phase (PVP) imaging, in the detection and characterization of hepatocellular carcinomas. METHODS: The study included 40 patients (M = 26, F = 14) with histopathologically proven HCC. Age range was between 30-85 years (mean = 55) by following consecutive patients with cirrhosis in whom Hepatocellular carcinoma was diagnosed or suspected either by raised serum a (alpha)-fetoprotein level or Ultrasound. RESULTS: Biphasic contrast-enhanced examination revealed a total of 85 lesions in these 40 patients, out of which 13 were unifocal, 12 showed a dominant mass with satellite lesions, 2 showed cluster of contiguous nodules and 13 were multifocal HCCs. Mean diameter was 3.1 cm, ranging from 0.8 to 14 cm. On HAP imaging 85% were detected. (hyperattenuating = 69, hypoattenuating = 3) while on PVP imaging detectibility was only 48% (hyperattenuating = 2, hypoattenuating = 39). Hence detectibility was significantly (p = 0.008) superior in HAP as compared to PVP imaging. In 7 patients (17%) tumor was visible only on HAP images. Venous invasion was present in 12 patients (30%) while arterio-portal shunting was seen in 5 patients (13%). CONCLUSION: Biphasic contrast enhanced helical CT is a useful method in detection and characterization of HCC.


Asunto(s)
Carcinoma Hepatocelular/diagnóstico por imagen , Neoplasias Hepáticas/diagnóstico por imagen , Tomografía Computarizada por Rayos X , Adulto , Anciano , Anciano de 80 o más Años , Medios de Contraste , Diagnóstico Diferencial , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Tomografía Computarizada por Rayos X/métodos
8.
Am Fam Physician ; 58(1): 130-6, 1998 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-9672433

RESUMEN

Factors associated with an increased risk of thromboembolic events in patients with atrial fibrillation (AF) include increasing age, rheumatic heart disease, poor left ventricular function, previous myocardial infarction, hypertension and a past history of a thromboembolic event. Patients with AF should be considered for anticoagulation or antiplatelet therapy based on the patient's age, the presence of other risk factors for stroke and the risk of complications from anticoagulation. In general, patients with risk factors for stroke should receive warfarin anticoagulation, regardless of their age. In patients who are under age 65 and have no other risk factors for stroke, either aspirin therapy or no therapy at all is recommended. Aspirin or warfarin is recommended for use in patients between 65 and 75 years of age with no other risk factors, and warfarin is recommended for use in patients without risk factors who are older than 75 years of age.


Asunto(s)
Anticoagulantes/uso terapéutico , Fibrilación Atrial/complicaciones , Fibrilación Atrial/tratamiento farmacológico , Trastornos Cerebrovasculares/etiología , Trastornos Cerebrovasculares/prevención & control , Warfarina/uso terapéutico , Factores de Edad , Anciano , Anticoagulantes/efectos adversos , Fibrilación Atrial/epidemiología , Fibrilación Atrial/etiología , Cardioversión Eléctrica , Hemorragia/inducido químicamente , Humanos , Incidencia , Persona de Mediana Edad , Ensayos Clínicos Controlados Aleatorios como Asunto , Riesgo , Factores de Riesgo , Warfarina/efectos adversos
9.
Spectrochim Acta A Mol Biomol Spectrosc ; 53A(7): 1021-31, 1997 Jul 15.
Artículo en Inglés | MEDLINE | ID: mdl-9219374

RESUMEN

Fourier-transform Raman microscopic spectra of normal, untreated and bleached hair fibres are presented. Vibrational assignments are made and differences are ascribed to the production of cysteic acid from cysteine. Changes in conformation associated with the disulphide bond in the keratotic component are noted from the v(CSSC) vibrational modes at wave numbers near 500 cm-1. Raman spectra of hair root ends have also been investigated with a diminution in cysteine content being observed. Application of the technique to the biomedical investigation of healthy and diseased hair is proposed.


Asunto(s)
Cabello/química , Espectrometría Raman , Adolescente , Adulto , Aminoácidos/análisis , Niño , Ácido Cisteico/análisis , Cisteína/análisis , Disulfuros/química , Femenino , Análisis de Fourier , Humanos , Queratinas/química , Conformación Molecular , Conformación Proteica , Estructura Secundaria de Proteína
10.
Artículo en Inglés | MEDLINE | ID: mdl-9110436

RESUMEN

The FT-Raman spectra of mammalian and avian keratotic biopolymers have been recorded, including bull's horn, cat's claw, bird's feather quill, pheasant's beak and compared with the hard keratinous tissue, human nail and callus. Although there were similarities in all the spectra. particularly in the v(CH) stretching region, the 1450-1100 cm-1 region exhibited some differences ascribed to intramolecular skeletal backbone conformational changes. Of particular significance for human, mammalian and avian samples in the 1000-400 cm-1 wavenumber region were differences in the structurally important v(SS) and v(CS) bands, near 500 cm-1 and 630 cm-1 respectively. The amide I and III modes near 1650 and 1250 cm-1 respectively, demonstrate that the mammalian keratins studied exist predominantly in the alpha-helical conformation, whereas the avian keratins adopt the beta-sheet structure as the dominant conformation.


Asunto(s)
Aves , Queratinas/química , Aminoácidos/análisis , Animales , Pico/química , Biopolímeros , Callo Óseo/química , Disulfuros/química , Plumas/química , Pezuñas y Garras/química , Humanos , Mamíferos , Uñas/química , Conformación Proteica , Estructura Secundaria de Proteína , Espectroscopía Infrarroja por Transformada de Fourier
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