RESUMEN
Two children were found to have cyclic thrombocytopenia, recurring at regular intervals. Coagulation studies as well as immunologic evaluation did not reveal any abnormality. One of the patients continued to demonstrate the cyclic fluctuation in platelet counts despite corticosteroid therapy and showed no response to fresh frozen plasma infusion. One patient had been previously misdiagnosed as having idiopathic thrombocytopenic purpura (ITP), which might have caused problems if other therapies had been tried. The diagnosis of cyclic thrombocytopenia led to appropriate counseling and activity regulation.
Asunto(s)
Periodicidad , Trombocitopenia/diagnóstico , Niño , Humanos , Inmunoglobulinas/análisis , Masculino , Recuento de Plaquetas , Prednisona/uso terapéutico , Trombocitopenia/tratamiento farmacológico , Trombocitopenia/inmunologíaAsunto(s)
Leucemia Linfoide/epidemiología , Estaciones del Año , Adolescente , Niño , Preescolar , Estudios Transversales , Humanos , Lactante , Estados UnidosAsunto(s)
Leucemia Linfoide/epidemiología , Estaciones del Año , Adolescente , Niño , Preescolar , Femenino , Humanos , Lactante , Masculino , Conceptos Meteorológicos , NebraskaRESUMEN
Calcification occurring in the basal ganglia in children with acute lymphocyte leukemia following therapy is uncommon and to the best of our knowledge has not been reported prior to therapy. Eleven cases of bilateral symmetrical calcification in the basal ganglia were noted in 2350 CT scans, two being in children with acute lymphocytic leukemia. In one of the two cases, calcification was present prior to therapy.
Asunto(s)
Enfermedades de los Ganglios Basales/diagnóstico por imagen , Calcinosis/diagnóstico por imagen , Leucemia Linfoide/diagnóstico por imagen , Tomografía Computarizada por Rayos X , Enfermedades de los Ganglios Basales/etiología , Calcinosis/etiología , Niño , Preescolar , Quimioterapia Combinada , Humanos , Leucemia Linfoide/tratamiento farmacológico , Leucemia Linfoide/radioterapia , Masculino , Mercaptopurina/administración & dosificación , Metotrexato/administración & dosificación , Prednisona/administración & dosificación , Vincristina/administración & dosificaciónRESUMEN
We studied two children with neuroblastoma in whom hypercalcemia developed as the initial manifestation in one and during the course of therapy in the other. Serum parathyroid hormone activity was elevated in the patient in whom the test for it was performed. Mithramycin controlled the hypercalcemia in one patient and tumor resection with radiation therapy and chemotherapy was sufficient for control of this complication in the other.
Asunto(s)
Hipercalcemia/etiología , Neoplasias Abdominales/complicaciones , Resorción Ósea , Niño , Preescolar , Humanos , Hipercalcemia/diagnóstico , Hipercalcemia/terapia , Masculino , Neuroblastoma/complicaciones , Plicamicina/uso terapéuticoRESUMEN
A case of an 11-year-old Negro female with SC disease who sustained right eye injury with development of a massive and fatal sequestration crisis following ocular evisceration was presented. The inherent danger of SC disease in relation to surgical procedures and general anesthesia was stressed and recommendations as to preoperative management of SC disease was briefly discussed.
Asunto(s)
Anemia de Células Falciformes/complicaciones , Lesiones Oculares/complicaciones , Procedimientos Quirúrgicos Operativos/efectos adversos , Anemia de Células Falciformes/sangre , Bradicardia/complicaciones , Niño , Lesiones Oculares/cirugía , Femenino , Humanos , Fibrilación Ventricular/complicaciones , Heridas por Arma de Fuego/cirugíaRESUMEN
A case of a nine-year-old child with acute lymphocytic leukemia in remission who developed infectious parotitis with uveitis was presented. Ocular complications of mumps have been briefly discussed and the differential diagnosis particularly in relationship to leukemia have been emphasized. The significance of depressed cellular immunity in the development of this complication was entertained.
