A hybridized feature extraction for COVID-19 multi-class classification on computed tomography images.

COVID-19 has killed more than 5 million individuals worldwide within a short time. It is caused by SARS-CoV-2 which continuously mutates and produces more transmissible new different strains. It is therefore of great significance to diagnose COVID-19 early to curb its spread and reduce the death rate. Owing to the COVID-19 pandemic, traditional diagnostic methods such as reverse-transcription polymerase chain reaction (RT-PCR) are ineffective for diagnosis. Medical imaging is among the most effective techniques of respiratory disorders detection through machine learning and deep learning. However, conventional machine learning methods depend on extracted and engineered features, whereby the optimum features influence the classifier's performance. In this study, Histogram of Oriented Gradient (HOG) and eight deep learning models were utilized for feature extraction while K-Nearest Neighbour (KNN) and Support Vector Machines (SVM) were used for classification. A combined feature of HOG and deep learning feature was proposed to improve the performance of the classifiers. VGG-16 + HOG achieved 99.4 overall accuracy with SVM. This indicates that our proposed concatenated feature can enhance the SVM classifier's performance in COVID-19 detection.

SegEIR-Net: A Robust Histopathology Image Analysis Framework for Accurate Breast Cancer Classification.

BACKGROUND: Breast Cancer (BC) is a significant threat affecting women globally. An accurate and reliable disease classification method is required to get an early diagnosis. However, existing approaches lack accurate and robust classification. OBJECTIVE: This study aims to design a model to classify BC Histopathology images accurately by leveraging segmentation techniques. METHODS: This work proposes a combined segmentation and classification approach for classifying BC using histopathology images to address these issues. Chan-Vese algorithm is used for segmentation to accurately delineate regions of interest within the histopathology images, followed by the proposed SegEIR-Net (Segmentation using EfficientNet, InceptionNet, and ResNet) for classification. Bilateral Filtering is also employed for noise reduction. The proposed model uses three significant networks, ResNet, InceptionNet, and EfficientNet, concatenates the outputs from each block followed by Dense and Dropout layers. The model is trained on the breakHis dataset for four different magnifications and tested on BACH (BreAst Cancer Histology) and UCSB (University of California, Santa Barbara) datasets. RESULTS: SegEIR-Net performs better than the existing State-of-the-Art (SOTA) methods in terms of accuracy on all three datasets, proving the robustness of the proposed model. The accuracy achieved on breakHis dataset are 98.66%, 98.39%, 97.52%, 95.22% on different magnifications, and 93.33% and 96.55% on BACH and UCSB datasets. CONCLUSION: These performance results indicate the robustness of the proposed SegEIR-Net framework in accurately classifying BC from histopathology images.

Wearable Sensor Data Classification for Identifying Missing Transmission Sequence Using Tree Learning.

Wearable Sensor (WS) data accumulation and transmission are vital in analyzing the health status of patients and elderly people remotely. Through specific time intervals, the continuous observation sequences provide a precise diagnosis result. This sequence is however interrupted due to abnormal events or sensor or communicating device failures or even overlapping sensing intervals. Therefore, considering the significance of continuous data gathering and transmission sequence for WS, this article introduces a Concerted Sensor Data Transmission Scheme (CSDTS). This scheme endorses aggregation and transmission that aims at generating continuous data sequences. The aggregation is performed considering the overlapping and non-overlapping intervals from the WS sensing process. Such concerted data aggregation generates fewer chances of missing data. In the transmission process, allocated first-come-first-serve-based sequential communication is pursued. In the transmission scheme, a pre-verification of continuous or discrete (missing) transmission sequences is performed using classification tree learning. In the learning process, the accumulation and transmission interval synchronization and sensor data density are matched for preventing pre-transmission losses. The discrete classified sequences are thwarted from the communication sequence and are transmitted post the alternate WS data accumulation. This transmission type prevents sensor data loss and reduces prolonged wait times.

EEI-IoT: Edge-Enabled Intelligent IoT Framework for Early Detection of COVID-19 Threats.

Coronavirus disease 2019 (COVID-19) has caused severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) across the globe, impacting effective diagnosis and treatment for any chronic illnesses and long-term health implications. In this worldwide crisis, the pandemic shows its daily extension (i.e., active cases) and genome variants (i.e., Alpha) within the virus class and diversifies the association with treatment outcomes and drug resistance. As a consequence, healthcare-related data including instances of sore throat, fever, fatigue, cough, and shortness of breath are given due consideration to assess the conditional state of patients. To gain unique insights, wearable sensors can be implanted in a patient's body that periodically generates an analysis report of the vital organs to a medical center. However, it is still challenging to analyze risks and predict their related countermeasures. Therefore, this paper presents an intelligent Edge-IoT framework (IE-IoT) to detect potential threats (i.e., behavioral and environmental) in the early stage of the disease. The prime objective of this framework is to apply a new pre-trained deep learning model enabled by self-supervised transfer learning to build an ensemble-based hybrid learning model and to offer an effective analysis of prediction accuracy. To construct proper clinical symptoms, treatment, and diagnosis, an effective analysis such as STL observes the impact of the learning models such as ANN, CNN, and RNN. The experimental analysis proves that the ANN model considers the most effective features and attains a better accuracy (~98.3%) than other learning models. Also, the proposed IE-IoT can utilize the communication technologies of IoT such as BLE, Zigbee, and 6LoWPAN to examine the factor of power consumption. Above all, the real-time analysis reveals that the proposed IE-IoT with 6LoWPAN consumes less power and response time than the other state-of-the-art approaches to infer the suspected victims at an early stage of development of the disease.

Smart Graphene-Based Electrochemical Nanobiosensor for Clinical Diagnosis: Review.

The technological improvement in the field of physics, chemistry, electronics, nanotechnology, biology, and molecular biology has contributed to the development of various electrochemical biosensors with a broad range of applications in healthcare settings, food control and monitoring, and environmental monitoring. In the past, conventional biosensors that have employed bioreceptors, such as enzymes, antibodies, Nucleic Acid (NA), etc., and used different transduction methods such as optical, thermal, electrochemical, electrical and magnetic detection, have been developed. Yet, with all the progresses made so far, these biosensors are clouded with many challenges, such as interference with undesirable compound, low sensitivity, specificity, selectivity, and longer processing time. In order to address these challenges, there is high need for developing novel, fast, highly sensitive biosensors with high accuracy and specificity. Scientists explore these gaps by incorporating nanoparticles (NPs) and nanocomposites (NCs) to enhance the desired properties. Graphene nanostructures have emerged as one of the ideal materials for biosensing technology due to their excellent dispersity, ease of functionalization, physiochemical properties, optical properties, good electrical conductivity, etc. The Integration of the Internet of Medical Things (IoMT) in the development of biosensors has the potential to improve diagnosis and treatment of diseases through early diagnosis and on time monitoring. The outcome of this comprehensive review will be useful to understand the significant role of graphene-based electrochemical biosensor integrated with Artificial Intelligence AI and IoMT for clinical diagnostics. The review is further extended to cover open research issues and future aspects of biosensing technology for diagnosis and management of clinical diseases and performance evaluation based on Linear Range (LR) and Limit of Detection (LOD) within the ranges of Micromolar µM (10-6), Nanomolar nM (10-9), Picomolar pM (10-12), femtomolar fM (10-15), and attomolar aM (10-18).

Effect of Gaussian filtered images on Mask RCNN in detection and segmentation of potholes in smart cities.

Accidents have contributed a lot to the loss of lives of motorists and serious damage to vehicles around the globe. Potholes are the major cause of these accidents. It is very important to build a model that will help in recognizing these potholes on vehicles. Several object detection models based on deep learning and computer vision were developed to detect these potholes. It is very important to develop a lightweight model with high accuracy and detection speed. In this study, we employed a Mask RCNN model with ResNet-50 and MobileNetv1 as the backbone to improve detection, and also compared the performance of the proposed Mask RCNN based on original training images and the images that were filtered using a Gaussian smoothing filter. It was observed that the ResNet trained on Gaussian filtered images outperformed all the employed models.

A systematic approach for COVID-19 predictions and parameter estimation.

The world is currently facing a pandemic called COVID-19 which has drastically changed our human lifestyle, affecting it badly. The lifestyle and the thought processes of every individual have changed with the current situation. This situation was unpredictable, and it contains a lot of uncertainties. In this paper, the authors have attempted to predict and analyze the disease along with its related issues to determine the maximum number of infected people, the speed of spread, and most importantly, its evaluation using a model-based parameter estimation method. In this research the Susceptible-Infectious-Recovered model with different conditions has been used for the analysis of COVID-19. The effects of lockdown, the light switch method, and parameter variations like contact ratio and reproduction number are also analyzed. The authors have attempted to study and predict the lockdown effect, particularly in India in terms of infected and recovered numbers, which show substantial improvement. A disease-free endemic stability analysis using Lyapunov and LaSalle's method is presented, and novel methods such as the convalescent plasma method and the Who Acquires Infection From Whom method are also discussed, as they are considered to be useful in flattening the curve of COVID-19.

ANFIS for prediction of epidemic peak and infected cases for COVID-19 in India.

Corona Virus Disease 2019 (COVID-19) is a continuing extensive incident globally affecting several million people's health and sometimes leading to death. The outbreak prediction and making cautious steps is the only way to prevent the spread of COVID-19. This paper presents an Adaptive Neuro-fuzzy Inference System (ANFIS)-based machine learning technique to predict the possible outbreak in India. The proposed ANFIS-based prediction system tracks the growth of epidemic based on the previous data sets fetched from cloud computing. The proposed ANFIS technique predicts the epidemic peak and COVID-19 infected cases through the cloud data sets. The ANFIS is chosen for this study as it has both numerical and linguistic knowledge, and also has ability to classify data and identify patterns. The proposed technique not only predicts the outbreak but also tracks the disease and suggests a measurable policy to manage the COVID-19 epidemic. The obtained prediction shows that the proposed technique very effectively tracks the growth of the COVID-19 epidemic. The result shows the growth of infection rate decreases at end of 2020 and also has delay epidemic peak by 40-60 days. The prediction result using the proposed ANFIS technique shows a low Mean Square Error (MSE) of 1.184 × 10-3 with an accuracy of 86%. The study provides important information for public health providers and the government to control the COVID-19 epidemic.

A Novel Approach for Multichannel Epileptic Seizure Classification Based on Internet of Things Framework Using Critical Spectral Verge Feature Derived from Flower Pollination Algorithm.

A novel approach for multichannel epilepsy seizure classification which will help to automatically locate seizure activity present in the focal brain region was proposed. This paper suggested an Internet of Things (IoT) framework based on a smart phone by utilizing a novel feature termed multiresolution critical spectral verge (MCSV), based on frequency-derived information for epileptic seizure classification which was optimized using a flower pollination algorithm (FPA). A wireless sensor technology (WSN) was utilized to record the electroencephalography (EEG) signal of epileptic patients. Next, the EEG signal was pre-processed utilizing a multiresolution-based adaptive filtering (MRAF) method. Then, the maximal frequency point at which the power spectral density (PSD) of each EEG segment was greater than the average spectral power of the corresponding frequency band was computed. This point was further optimized to extract a point termed as critical spectral verge (CSV) to extract the exact high frequency oscillations representing the actual seizure activity present in the EEG signal. Next, a support vector machine (SVM) classifier was used for channel-wise classification of the seizure and non-seizure regions using CSV as a feature. This process of classification using the CSV feature extracted from the MRAF output is referred to as the MCSV approach. As a final step, cloud-based services were employed to analyze the EEG information from the subject's smart phone. An exhaustive analysis was undertaken to assess the performance of the MCSV approach for two datasets. The presented approach showed an improved performance with a 93.83% average sensitivity, a 97.94% average specificity, a 97.38% average accuracy with the SVM classifier, and a 95.89% average detection rate as compared with other state-of-the-art studies such as deep learning. The methods presented in the literature were unable to precisely localize the origination of the seizure activity in the brain region and reported a low seizure detection rate. This work introduced an optimized CSV feature which was effectively used for multichannel seizure classification and localization of seizure origination. The proposed MCSV approach will help diagnose epileptic behavior from multichannel EEG signals which will be extremely useful for neuro-experts to analyze seizure details from different regions of the brain.

IoT-Based Humanoid Software for Identification and Diagnosis of Covid-19 Suspects.

COVID-19 pandemic has a catastrophic consequence globally since its first case was detected in December 2019, with an aggressive spread. Currently an exponential growth is expected. If not diagnosed at the proper time, COVID-19 may lead to death of the infected individuals. Thus, continuous screening, early diagnosis and prompt actions are crucial to control the spread and reduce the mortality. In this paper we focus on developing a Medical Diagnosis Humanoid (MDH) which is a cost effective, safety critical mobile robotic system that provides a complete diagnostic test to check whether an individual is infected by Covid-19 or not. This paper highlights the development of a system based on Artificial Intelligence for Medical Science, where humanoids can navigate through desired destinations, diagnose an individual for Covid-19 through various parameters and make a survey of a locality for the same. The humanoid uses the concept of real time data sensing and processing through machine learning produced by various sensors used in the context.

Computer aided detection of tuberculosis using two classifiers.

Tuberculosis caused by Mycobacterium tuberculosis have been a major challenge for medical and healthcare sectors in many underdeveloped countries with limited diagnosis tools. Tuberculosis can be detected from microscopic slides and chest X-ray but as a result of the high cases of tuberculosis, this method can be tedious for both microbiologist and Radiologist and can lead to miss-diagnosis. The main objective of this study is to addressed these challenges by employing Computer Aided Detection (CAD) using Artificial Intelligence-driven models which learn features based on convolution and result in an output with high accuracy. In this paper, we described automated discrimination of X-ray and microscopic slide images of tuberculosis into positive and negative cases using pretrained AlexNet Models. The study employed Chest X-ray dataset made available on Kaggle repository and microscopic slide images from both Near East university hospital and Kaggle repository. For classification of tuberculosis and healthy microscopic slide using AlexNet+Softmax, the model achieved accuracy of 98.14%. For classification of tuberculosis and healthy microscopic slide using AlexNet+SVM, the model achieved 98.73% accuracy. For classification of tuberculosis and healthy chest X-ray images using AlexNet+Softmax, the model achieved accuracy of 98.19%. For classification of tuberculosis and healthy chest X-ray images using AlexNet+SVM, the model achieved 98.38% accuracy. The result obtained has shown to outperformed several studies in the current literature. Future studies will attempt to integrate Internet of Medical Things (IoMT) for the design of IoMT/AI-enabled platform for detection of Tuberculosis from both X-ray and Microscopic slide images.

Towards an effective model for lung disease classification: Using Dense Capsule Nets for early classification of lung diseases.

Machine Learning and computer vision have been the frontiers of the war against the COVID-19 Pandemic. Radiology has vastly improved the diagnosis of diseases, especially lung diseases, through the early assessment of key disease factors. Chest X-rays have thus become among the commonly used radiological tests to detect and diagnose many lung diseases. However, the discovery of lung disease through X-rays is a significantly challenging task depending on the availability of skilled radiologists. There has been a recent increase in attention to the design of Convolution Neural Networks (CNN) models for lung disease classification. A considerable amount of training dataset is required for CNN to work, but the problem is that it cannot handle translation and rotation correctly as input. The recently proposed Capsule Networks (referred to as CapsNets) are new automated learning architecture that aims to overcome the shortcomings in CNN. CapsNets are vital for rotation and complex translation. They require much less training information, which applies to the processing of data sets from medical images, including radiological images of the chest X-rays. In this research, the adoption and integration of CapsNets into the problem of chest X-ray classification have been explored. The aim is to design a deep model using CapsNet that increases the accuracy of the classification problem involved. We have used convolution blocks that take input images and generate convolution layers used as input to capsule block. There are 12 capsule layers operated, and the output of each capsule is used as an input to the next convolution block. The process is repeated for all blocks. The experimental results show that the proposed architecture yields better results when compared with the existing CNN techniques by achieving a better area under the curve (AUC) average. Furthermore, DNet checks the best performance in the ChestXray-14 data set on traditional CNN, and it is validated that DNet performs better with a higher level of total depth.

Machine learning analysis on the impacts of COVID-19 on India's renewable energy transitions and air quality.

India is severely affected by the COVID-19 pandemic and is facing an unprecedented public health emergency. While the country's immediate measures focus on combating the coronavirus spread, it is important to investigate the impacts of the current crisis on India's renewable energy transition and air quality. India's economic slowdown is mainly compounded by the collapse of global oil prices and the erosion of global energy demand. A clean energy transition is a key step in enabling the integration of energy and climate. Millions in India are affected owing to fossil fuel pollution and the increasing climate heating that has led to inconceivable health impacts. This paper attempts to study the impact of COVID-19 on India's climate and renewable energy transitions through machine learning algorithms. India is observing a massive collapse in energy demand during the lockdown as its coal generation is suffering the worst part of the ongoing pandemic. During this current COVID-19 crisis, the renewable energy sector benefits from its competitive cost and the Indian government's must-run status to run generators based on renewable energy sources. In contrast to fossil fuel-based power plants, renewable energy sources are not exposed to the same supply chain disruptions in this current pandemic situation. India has the definite potential to surprise the global community and contribute to cost-effective decarbonization. Moreover, the country has a good chance of building more flexibility into the renewable energy sector to avoid an unstable future.

Hybridized sine cosine algorithm with convolutional neural networks dropout regularization application.

Deep learning has recently been utilized with great success in a large number of diverse application domains, such as visual and face recognition, natural language processing, speech recognition, and handwriting identification. Convolutional neural networks, that belong to the deep learning models, are a subtype of artificial neural networks, which are inspired by the complex structure of the human brain and are often used for image classification tasks. One of the biggest challenges in all deep neural networks is the overfitting issue, which happens when the model performs well on the training data, but fails to make accurate predictions for the new data that is fed into the model. Several regularization methods have been introduced to prevent the overfitting problem. In the research presented in this manuscript, the overfitting challenge was tackled by selecting a proper value for the regularization parameter dropout by utilizing a swarm intelligence approach. Notwithstanding that the swarm algorithms have already been successfully applied to this domain, according to the available literature survey, their potential is still not fully investigated. Finding the optimal value of dropout is a challenging and time-consuming task if it is performed manually. Therefore, this research proposes an automated framework based on the hybridized sine cosine algorithm for tackling this major deep learning issue. The first experiment was conducted over four benchmark datasets: MNIST, CIFAR10, Semeion, and UPS, while the second experiment was performed on the brain tumor magnetic resonance imaging classification task. The obtained experimental results are compared to those generated by several similar approaches. The overall experimental results indicate that the proposed method outperforms other state-of-the-art methods included in the comparative analysis in terms of classification error and accuracy.

Achieving data privacy for decision support systems in times of massive data sharing.

The world is suffering from a new pandemic of Covid-19 that is affecting human lives. The collection of records for Covid-19 patients is necessary to tackle that situation. The decision support systems (DSS) are used to gather that records. The researchers access the patient's data through DSS and perform predictions on the severity and effect of the Covid-19 disease; in contrast, unauthorized users can also access the data for malicious purposes. For that reason, it is a challenging task to protect Covid-19 patient data. In this paper, we proposed a new technique for protecting Covid-19 patients' data. The proposed model consists of two folds. Firstly, Blowfish encryption uses to encrypt the identity attributes. Secondly, it uses Pseudonymization to mask identity and quasi-attributes, then all the data links with one another, such as the encrypted, masked, sensitive, and non-sensitive attributes. In this way, the data becomes more secure from unauthorized access.

Current Technologies for Detection of COVID-19: Biosensors, Artificial Intelligence and Internet of Medical Things (IoMT): Review.

Despite the fact that COVID-19 is no longer a global pandemic due to development and integration of different technologies for the diagnosis and treatment of the disease, technological advancement in the field of molecular biology, electronics, computer science, artificial intelligence, Internet of Things, nanotechnology, etc. has led to the development of molecular approaches and computer aided diagnosis for the detection of COVID-19. This study provides a holistic approach on COVID-19 detection based on (1) molecular diagnosis which includes RT-PCR, antigen-antibody, and CRISPR-based biosensors and (2) computer aided detection based on AI-driven models which include deep learning and transfer learning approach. The review also provide comparison between these two emerging technologies and open research issues for the development of smart-IoMT-enabled platforms for the detection of COVID-19.

Local binary pattern and deep learning feature extraction fusion for COVID-19 detection on computed tomography images.

The deadly coronavirus virus (COVID-19) was confirmed as a pandemic by the World Health Organization (WHO) in December 2019. It is important to identify suspected patients as early as possible in order to control the spread of the virus, improve the efficacy of medical treatment, and, as a result, lower the mortality rate. The adopted method of detecting COVID-19 is the reverse-transcription polymerase chain reaction (RT-PCR), the process is affected by a scarcity of RT-PCR kits as well as its complexities. Medical imaging using machine learning and deep learning has proved to be one of the most efficient methods of detecting respiratory diseases, but to train machine learning features needs to be extracted manually, and in deep learning, efficiency is affected by deep learning architecture and low data. In this study, handcrafted local binary pattern (LBP) and automatic seven deep learning models extracted features were used to train support vector machines (SVM) and K-nearest neighbour (KNN) classifiers, to improve the performance of the classifier, a concatenated LBP and deep learning feature was proposed to train the KNN and SVM, based on the performance criteria, the models VGG-19 + LBP achieved the highest accuracy of 99.4%. The SVM and KNN classifiers trained on the hybrid feature outperform the state of the art model. This shows that the proposed feature can improve the performance of the classifiers in detecting COVID-19.

Deming least square regressed feature selection and Gaussian neuro-fuzzy multi-layered data classifier for early COVID prediction.

Coronavirus disease (COVID-19) is a harmful disease caused by the new SARS-CoV-2 virus. COVID-19 disease comprises symptoms such as cold, cough, fever, and difficulty in breathing. COVID-19 has affected many countries and their spread in the world has put humanity at risk. Due to the increasing number of cases and their stress on administration as well as health professionals, different prediction techniques were introduced to predict the coronavirus disease existence in patients. However, the accuracy was not improved, and time consumption was not minimized during the disease prediction. To address these problems, least square regressive Gaussian neuro-fuzzy multi-layered data classification (LSRGNFM-LDC) technique is introduced in this article. LSRGNFM-LDC technique performs efficient COVID prediction with better accuracy and lesser time consumption through feature selection and classification. The preprocessing is used to eliminate the unwanted data in input features. Preprocessing is applied to reduce the time complexity. Next, Deming Least Square Regressive Feature Selection process is carried out for selecting the most relevant features through identifying the line of best fit. After the feature selection process, Gaussian neuro-fuzzy classifier in LSRGNFM-LDC technique performs the data classification process with help of fuzzy if-then rules for performing prediction process. Finally, the fuzzy if-then rule classifies the patient data as lower risk level, medium risk level and higher risk level with higher accuracy and lesser time consumption. Experimental evaluation is performed by Novel Corona Virus 2019 Dataset using different metrics like prediction accuracy, prediction time, and error rate. The result shows that LSRGNFM-LDC technique improves the accuracy and minimizes the time consumption as well as error rate than existing works during COVID prediction.