Patient perspectives on ionising radiation exposure from computed tomography in Saudi Arabia: a knowledge and perception study.

The objective of this study was to evaluate patient knowledge and understanding of ionising radiation and dosage, as well as the accompanying risks related to computed tomography scans. A total of 412 outpatients who underwent computed tomography (CT) scans were surveyed to assess their understanding of radiation dose and exposure risks. CT was correctly classified as an ionising radiation by 56.8% of the respondents. More than half of the patients reported that a CT scan increases the probability of inducing cancer. Awareness of varying radiation doses in different CT exams was noted in 75.2% of patients, but only 21.4% reported having discussions with their physician about radiation dose. Gender, age and employment were significantly correlated with knowledge levels. The survey findings indicate a limited understanding of the hazards associated with ionising radiation used in CT scans, highlighting a need for increased awareness and education on radiation protection to ensure informed consent.

Estimation of organ and effective doses of CBCT scans of radiotherapy using size-specific field of view (FOV): a Monte Carlo study.

The kV cone beam computed tomography (CBCT) is one of the most common imaging modalities used for image-guided radiation therapy (IGRT) procedures. Additional doses are delivered to patients, thus assessment and optimization of the imaging doses should be taken into consideration. This study aimed to investigate the influence of using fixed and patient-specific FOVs on the patient dose. Monte Carlo simulations were performed to simulate kV beams of the imaging system integrated into Truebeam linear accelerator using BEAMnrc code. Organ and size-specific effective doses resulting from chest and pelvis scanning protocols were estimated with DOSXYZnrc code using a phantom library developed by the National Cancer Institute (NCI) of the US. The library contains 193 (100 male and 93 female) mesh-type computational human adult phantoms, and it covers a large ratio of patient sizes with heights and weights ranging from 150 to 190 cm and 40 to 125 kg. The imaging doses were assessed using variable FOV of three sizes, small (S), medium (M), and large (L) for each scan region. The results show that the FOV and the patient size played a major role in the scan dose. The average percentage differences (PDs) for doses of organs that were fully inside the different FOVs were relatively low, all within 11% for both protocols. However, doses to organs that were scanned partially or near the FOVs were affected significantly. For the chest protocol, the inclusion of the thyroid in the scan field could give a dose of 1-7 mGy/100 mAs to the thyroid, compared to 0.4-1 mGy/100 mAs when it was excluded. Similarly, on average, testes doses could be 6 mGy/100 mAs for the male pelvis protocol compared to 3 mGy/100 mAs when it did not lie in the field irradiated. These dose differences resulted in an average increase of up to 27% in the size-specific effective dose of the protocols. Since changing the field size is possible for CBCT scans, the results suggest that patient-specific scanning protocols could be applied for each scan area in a manner similar to that used for CT scans. Adjustment of the FOV size should be subject to the clinical needs, and assist in improving the treatment accuracy. The patient's height and weight might be considered as the main factors upon which, the selection of the appropriate patient-specific protocol is based. This approach should optimize the imaging doses used for IGRT procedures by minimizing doses of a large ratio of patients.

Estimation of size-specific dose estimate (SSDE) of CT scans using an effective diameter electron density.

OBJECTIVE: An assessment of the effective diameter of a patient's body using electron densities of tissues inside the scan area (Deffρe) was proposed to overcome challenges associated with the estimation of water-equivalent diameter (Dw), which is used for size-specific dose estimate (SSDE). The aims of this study were to (1) investigate the Deffρe method in two different forms using a wide range of patient sizes and scanning protocols, and (2) compare between four methods used to estimate the patient size for SSDE. MATERIALS AND METHODS: Under IRB approval, a total of 350 patients of varying sizes have been collected retrospectively from the Hospital. The Dw values were assessed over six different CT body protocols: (1) chest with contrast media, (2) chest High-Resolution Computed Tomography (HRCT) without contrast media, (3) abdomen-pelvis with contrast media, (4) abdomen-pelvis without contrast media, (5) chest-abdomen-pelvis with contrast media, and (6) pelvis without contrast media. A MATLAB-based code was developed in-house to assess the size of each patient using the conventional effective diameter method (Deff), Deffρe by correcting either both the lateral (LAT) and anterior-posterior (AP) dimensions (Deff,LAT+APρe) or LAT only (Deff,LATρe), and Dw at the mid-CT slice of the patient images. RESULTS: The results of Deff,LAT+APρe and Deff,LATρe provided a better estimation for the chest protocols with the averages of absolute percentage difference (PD) values in the range of 3 - 7 % for all patient sizes as compared to the Dw method, whereas the averages of PD values for the Deff method were 9 - 15 %. However, Deff gave a better estimation for Dw values for the other body protocols, with differences of 2 - 4 %, which were lower than those obtained with the Deff,LAT+APρe and Deff,LATρe methods. For the chest protocols, statistically significant differences were found between Deff and the other methods, but there were no significant differences between all the methods for the other scanning protocols. The results show that the correction of both dimensions, LAT and AP, did not improve the accuracy of the Deffρe method, and, for most protocols, Deff,LAT+APρe gave larger range differences compared to those based on correction of the LAT dimension only. CONCLUSION: If the Dw cannot be assessed, the Deff,LATρe method may only be considered for the chest protocols as an alternative approach. The Deff method may also be used for all regions taking into account the application of a correction factor for the chest protocols to avoid a significant under or overestimation of the patient dose.

The prevalence of harassment of diagnostic radiography and radiation therapy students whilst on clinical placement in the Republic of Ireland.

Objective: To determine if student radiographers and radiation therapists experience harassment (verbal, physical or sexual) while on clinical placement and their awareness of policies in place to report such incidents.Methods: An online questionnaire developed from the World Health Organisation's questionnaire on workplace violence in healthcare and the higher education authority (HEA) national survey of student experiences of sexual violence and harassment in Irish HEIs was used. Undergraduate and postgraduate diagnostic radiography and radiation therapy students in the Republic of Ireland to be included and have completed a minimum of four weeks of clinical placement. Our of 256 students, 98 filled out the survey.Results: Forty-one per cent (n = 40) of students reported experiencing at least one incident of harassment. Thirteen per cent reported experiencing two forms of harassment, and 2 students reported experiencing verbal, physical and sexual harassment. Verbal harassment (n = 33) and sexual (n = 16) were the most common form of harassment while physical harassment was experienced 7 participants. Ninety-one per cent (n = 88) of participants reported they don't believe they have received sufficient training in dealing with incidents of physical, verbal or sexual harassment.Conclusion: Harassment of student radiographers and radiation therapists is occurring while on placement. Male patients are the modal perpetrator, and most incidents go unreported. Students are not empowered to report an incident of harassment and are sometimes unaware of how to report harassment.

Provision of Safe Anesthesia in Magnetic Resonance Environments: Degree of Compliance with International Guidelines in Saudi Arabia.

BACKGROUND: The lack of local guidelines and regulations for the administration of anesthesia in magnetic resonance imaging (MRI) units presents a potential risk to patient safety in Saudi Arabia. Hence, this study aimed to evaluate the extent to which hospitals in Saudi Arabia follow international guidelines and recommendations for the safe and effective administration of anesthesia in an MRI environment. METHODS: This study used a questionnaire that was distributed to 31 medical facilities in Saudi Arabia that provided anesthesia in MRI units. RESULTS: The findings of the study revealed that the mean compliance with the 17 guidelines across the 31 sites was 77%; 5 of the 31 sites (16.1%) had a compliance rate of less than 50% with the recommended guidelines. Only 19.4% of the institutes provided general safety education. Communication breakdowns between anesthesia providers and MRI teams were reported. CONCLUSIONS: To conclude, this survey highlights the status of anesthesia standards in Saudi Arabian MRI units and emphasizes areas that require better adherence to international guidelines. The results call for targeted interventions, including the formulation of specific national anesthesia guidelines for MRI settings. Communication breakdowns between anesthesia providers and MRI teams were reported at a rate of 83.9% during the administration of a gadolinium contrast agent. There were additional breakdowns, particularly for high-risk patients with implants, such as impaired respirators (74.2%), thus requiring further investigation due to potential safety incidents during MRI procedures. While considering the limitations of this study, such as potential biases and the low response rate, it provides a valuable foundation for refining protocols and promoting standardized practices in Saudi Arabian healthcare.

The effect of contact radiation shielding on breast dose during CT abdomen-pelvis: a phantom study.

This study aims to investigate if contact shielding reduces breast radiation dose during computed tomography (CT) abdomen-pelvis examinations using automatic tube current modulation to protect one of the four most radiosensitive organs during CT examinations. Dose measurements were taken with and without contact shielding across the anterior and lateral aspects of the breasts and with and without organ dose modulation (ODM) to quantify achievable dose reductions. Although there are no statistically significant findings, when comparing with and without shielding, the mean breast surface dose was reduced by 0.01 µSv without ODM (1.92-1.91 µSv, p = 0.49) and increased by 0.03 µSv with ODM (1.53-1.56 µSv, p = 0.44). Comparing with and without ODM, the mean breast surface dose was reduced by 0.35 µSv with shielding (1.91-1.56 µSv, p = 0.24) and by 0.39 µSv without shielding (1.92-1.53 µSv, p = 0.17). The addition of contact shielding does not provide significant breast surface radiation dose reduction during CT abdomen-pelvis.

Modification of Dispersin B with Cyclodextrin-Ciprofloxacin Derivatives for Treating Staphylococcal.

To address the high tolerance of biofilms to antibiotics, it is urgent to develop new strategies to fight against these bacterial consortia. An innovative antibiofilm nanovector drug delivery system, consisting of Dispersin B-permethylated-ß-cyclodextrin/ciprofloxacin adamantyl (DspB-ß-CD/CIP-Ad), is described here. For this purpose, complexation assays between CIP-Ad and (i) unmodified ß-CD and (ii) different derivatives of ß-CD, which are 2,3-O-dimethyl-ß-CD, 2,6-O-dimethyl-ß-CD, and 2,3,6-O-trimethyl-ß-CD, were tested. A stoichiometry of 1/1 was obtained for the ß-CD/CIP-Ad complex by NMR analysis. Isothermal Titration Calorimetry (ITC) experiments were carried out to determine Ka, ΔH, and ΔS thermodynamic parameters of the complex between ß-CD and its different derivatives in the presence of CIP-Ad. A stoichiometry of 1/1 for ß-CD/CIP-Ad complexes was confirmed with variable affinity according to the type of methylation. A phase solubility study showed increased CIP-Ad solubility with CD concentration, pointing out complex formation. The evaluation of the antibacterial activity of CIP-Ad and the 2,3-O-dimethyl-ß-CD/CIP-Ad or 2,3,6-O-trimethyl-ß-CD/CIP-Ad complexes was performed on Staphylococcus epidermidis (S. epidermidis) strains. The Minimum Inhibitory Concentration (MIC) studies showed that the complex of CIP-Ad and 2,3-O-dimethyl-ß-CD exhibited a similar antimicrobial activity to CIP-Ad alone, while the interaction with 2,3,6-O-trimethyl-ß-CD increased MIC values. Antimicrobial assays on S. epidermidis biofilms demonstrated that the synergistic effect observed with the DspB/CIP association was partly maintained with the 2,3-O-dimethyl-ß-CDs/CIP-Ad complex. To obtain this "all-in-one" drug delivery system, able to destroy the biofilm matrix and release the antibiotic simultaneously, we covalently grafted DspB on three carboxylic permethylated CD derivatives with different-length spacer arms. The strategy was validated by demonstrating that a DspB-permethylated-ß-CD/ciprofloxacin-Ad system exhibited efficient antibiofilm activity.

The effect of breast shielding outside the field of view on breast entrance surface dose in axial X-ray examinations: a phantom study.

PURPOSE: The purpose of this study was to evaluate the effect of outside-field-of-view (FOV) lead shielding on the entrance surface dose (ESD) of the breast on an anthropomorphic X-ray phantom for a variety of axial skeleton X-ray examinations. METHODS: Using an anthropomorphic phantom and radiation dosimeter, the ESD of the breast was measured with and without outside-FOV shielding in anterior-posterior (AP) abdomen, AP cervical spine, occipitomental 30° (OM30) facial bones, AP lumbar spine, and lateral lumbar spine radiography. The effect of several exposure parameters, including a low milliampere-seconds technique, grid use, automatic exposure control use, wraparound lead (WAL) use, trolley use, and X-ray table use, on the ESD of the breast with and without outside-FOV shielding was investigated. The mean ESD (µSv) and standard deviation for each radiographic protocol were calculated. A one-tailed Student's t-test was carried out to evaluate whether ESD to the breast was reduced with the use of outside-FOV shielding. RESULTS: A total of 920 breast ESD measurements were recorded across the different protocol parameters. The largest decrease in mean ESD of the breast with outside-FOV shielding was 0.002 µSv (P = 0.084), recorded in the AP abdomen on the table with a grid, OM30 on the table with a grid, OM30 standard protocol on the trolley, and OM30 on the trolley with WAL protocols. This decrease was found to be statistically non-significant. CONCLUSION: This study found no significant decrease in the ESD of the breast with the use of outside-FOV shielding for the AP abdomen, AP cervical spine, OM30 facial bones, AP lumbar spine, or lateral lumbar spine radiography across a range of protocols.

Safety Survey on Lone Working Magnetic Resonance Imaging Technologists in Saudi Arabia.

PURPOSE: The American College of Radiology (ACR) requires MR personnel not to work alone due to the increased risk of safety issues such as projectiles, aggressive patients, and technologist fatigue. As a result, we intend to assess the current safety of lone-working MRI technologists in MRI departments in Saudi Arabia. MATERIALS AND METHODS: A cross-sectional study using a self-report questionnaire was conducted in 88 Saudi hospitals. RESULTS: A response rate of 64% (174/270) was obtained among the 270 MRI technologists which were identified. The study discovered that 86% of MRI technologists had prior experience working alone. In terms of MRI safety training, 63% of MRI technologists received such training. A question about lone MRI workers' awareness of the ACR's recommendations revealed that 38% were unaware of such recommendations. Furthermore, 22% were misinformed, believing that working alone in an MRI unit is optional or depends on the individual's desire to work alone. Working alone has the primary consequence of being statistically significantly associated with projectile/object-related accidents/mistakes (p = 0.03). CONCLUSION: Saudi Arabian MRI technologists have extensive experience working alone without supervision. Most MRI technologists are unaware of lone working regulations, which has raised concerns about accidents/mistakes. There is a need for MRI safety training and adequate practical experience to raise awareness of MRI safety regulations and policies related to lone working among departments and MRI workers.

JUSTIFICATION OF IMAGING IN DENTAL CLINICS: DOES RADIATION KNOWLEDGE PLAY A ROLE?

The study aims to investigate dentists' knowledge and consideration of radiation in relation to their referral practices and use of referral guidelines for imaging in Saudi Arabia. A cross-sectional study was conducted among dentists in different occupational positions in Saudi Arabia. The analysis showed that 68% of the dentists knew of imaging referral guidelines to consult before ordering an imaging exam. However, more than a quarter of the sample did not use them. More than half of responders estimated the average effective dose correctly for intraoral radiography, 44.8% for panoramic radiography, 53.4% for cone beam dental computed tomography (CT) and 47.8% for a study of dental implants/jaws using CT. Limited radiation knowledge and lack of use of proper referral guidelines among dentists indicate that the imaging referral justification process must be improved. The study concluded that radiation knowledge plays a critical role regarding image justification in dental clinics.

Assessment of Knowledge and Awareness About Breast Self-Examination Among University Female Students in Saudi Arabia.

Objective: This study aims to evaluate the knowledge and awareness of female university students in Saudi Arabia about breast self-examination (BSE). Methods: From January to March 2022, an online self-administered questionnaire covering socio-demographic data and BSE Knowledge was distributed to female students enrolled in Saudi universities. The survey link was disseminated online and through student leaders. Mann-Whitney and Kruskal-Wallis tests were used to determine associations between the categorical variables and the BSE knowledge scores. Logistic regression was used to report the best predictor(s) for BSE knowledge. Results: Among 668 respondents, 65.5% were aged between 20 and 24 years, 47.8% were taking health-related courses, 69.2% were from urban localities, and 90.6% had no family history of breast cancer. Only 4.2% showed adequate knowledge about BSEs. Students studying in health sciences had a significantly better BSE knowledge score (p = 0.01). Moreover, 26.5% knew that a BSE has to be completed each month, and a similar percentage of students were aware that a BSE should not be completed during the menstrual cycle. Approximately half of the students knew that 20 years old is the recommended age to start BSEs. Seventy-two percent were aware that they must look for abnormal breast changes and the importance of feeling the axillary area when performing a BSE. Additionally, 55.2% were aware that most breast masses are detected by women themselves. Conclusion: Saudi female students' knowledge about BSEs is inadequate. It is advisable that BSE knowledge and practice be incorporated into the curriculum of middle and high schools, as well as university students' programs.

Incidence of Gallbladder Stone Formation After Bariatric Surgery Using Ultrasound Imaging in the Southern Region of Saudi Arabia.

Background Bariatric surgery is performed for accomplishing weight loss, which can save patients from diseases associated with morbid obesity. However, rapid weight loss is one of the most important risk factors contributing to the formation of gallbladder stones. The aim of this study is to investigate the prevalence of gallstone formation among patients in the southern region of Saudi Arabia who underwent bariatric surgery and to evaluate the association between several parameters and gallstone development in these patients. Methods A retrospective study was conducted including 57 patients who did not have gallstones in the preoperative abdominal ultrasound examinations. Demographic data, such as age and gender, were obtained along with other parameters like weight loss after surgery, and time elapsed between the surgery to post-surgery US examination. The findings of the US examinations were collected and analyzed. Data were analyzed to obtain descriptive and inferential statistics. A correlation matrix to investigate the dependence between variables was conducted. Results Patients in this study underwent either sleeve gastrectomy (87.7% [n = 50]) or gastric banding procedures (12.3% [n = 7]). The occurrence of cholecystectomy was 46% after sleeve gastrectomy and 71.1% after gastric band procedures. The majority of the patients (57.9%) lost weight after surgery in the range of 20 to 40 kg. The time elapses between the surgery to post-surgery ultrasonography examination varied among patients, where less than one year, one to three years, and three to six years accounted for 47.4%, 43.9%, and 8.8%, respectively. Gallstone formation after the surgery was found in 35 (61.4%) of the total cases. Among patients who developed gallbladder stones after bariatric surgery, 62.9%, 28.4%, and 8.6% were within less than one year, one to three years, and three to six years, respectively. The results suggest a statistically significant correlation betweengallstone formation and​​​ the time elapsed after the surgery (P = 0.008) and the type of bariatric surgery (P = 0.006). Conclusion The current study found that the overall incidence rate of gallbladder stones after bariatric surgery is 61.4%. The study assumed a possible higher incidence of gallbladder stones following bariatric surgery among the population in the southern region of Saudi Arabia compared to incidence rates reported in the literature. The type of bariatric surgery and the time elapsed after the surgery were found to be of value in predicting the formation of gallstones.

Musculoskeletal symptoms among radiation technologists in Saudi Arabia: prevalence and causative factors.

BACKGROUND: Radiation technologists usually perform several physical tasks as part of their work routine that are related to imaging equipment and handling patients. These kinds of physical activities increase their risk of developing musculoskeletal symptoms (MSS). PURPOSE: To determine the prevalence and causative factors of MSS among radiation technologists in Saudi Arabia. MATERIAL AND METHODS: A previously validated and published questionnaire was sent electronically to 800 radiation technologists in Saudi Arabia. It focused on the presence and prior diagnosis of MSS. Questions to determine risk factors were included. RESULTS: A total of 381 responses were obtained. MSS were indicated by 326 responders (85.6%). Furthermore, it was reported that 309 responders (81.1%) spent more than 2 h per day in awkward postures. Of the responders, 164 (43%) stated that they worked 4 h per day on a personal computer or PACS. The most frequently selected reasons for MSS included patient transfer (50.6%), chairs (38.5%), lead aprons (25.6%), moving heavy equipment (23.1%), and fixed table height (19.4%). An association between work-related MSS and gender was observed (χ2(1) = 5.338; P = 0.021). Similarly, an association between work-related MSS and age was also observed (χ2(3) = 48.58; P = 0.000). CONCLUSION: Radiation technologists in Saudi Arabia reported a fairly high incidence of MSS, more commonly among female and senior workers. To have a better and safer workplace for radiation technologists, this study suggests preventive measures on organizational and individual levels.

Estimation of radiation doses and lifetime attributable risk of radiation-induced cancer in the uterus and prostate from abdomen pelvis CT examinations.

Computed tomography (CT) scans are one of the most common radiation imaging modalities, and CT scans are rising steadily worldwide. CT has the potential to enhance radiography practice, but it also has the risk of drastically increasing patient doses. One CT procedure for the abdomen pelvis (AP) area can expose a patient's prostate or uterus to a substantial radiation dose, leading to concerns about radiation-induced cancer. This study aimed to estimate organ doses of the uterus and prostate and evaluate the lifetime attributable risk (LAR) of cancer incidence and mortality resulting from AP CT examinations. This retrospective study included 665 patients, of which 380 (57%) were female, and 285 (43%) were male. Data were collected from the picture archiving and communication system for AP CT procedures and exposure parameter data. Organ doses for the uterus and prostate were calculated using National Cancer Institute CT (NCICT) software. Based on the risk models proposed by the BEIR VII report, the calculated organ doses were used to estimate the LAR of prostate and uterus cancer incidence and mortality due to radiation exposure from AP CT procedures. The mean effective dose resulting from AP CT for females and males was 5.76 ± 3.22 (range: 1.13-12.71 mSv) and 4.37 ± 1.66 mSv (range: 1.36-8.07 mSv), respectively. The mean organ dose to the uterus was 10.86 ± 6.09 mGy (range: 2.13-24.06 mGy). The mean organ dose to the prostate was 7.00 ± 2.66 mGy (range: 2.18-12.94 mGy). The LAR of uterus and prostate cancer incidence was 1.75 ± 1.19 cases and 2.24 ± 1.06 cases per 100,000 persons, respectively. The LAR of cancer mortality rates from uterus and prostate cancers were 0.36 ± 0.22 and 0.48 ± 0.18 cases per 100,000 persons, respectively. The LAR of prostate and uterus cancer occurrence and mortality from radiation doses with AP CT procedures was low but not trivial. Therefore, efforts should be made to lower patient doses while retaining image quality. Although the minimization of the patient's radiation dose must guide clinical practice, the estimated slight increase in risk could aid in easing fears regarding well-justified AP CT procedures.

OCCUPATIONAL DOSE OF OPERATORS OF NUCLEAR MOISTURE DENSITY GAUGES USED IN PAVEMENT CONSTRUCTION IN SAUDI ARABIA USING THERMOLUMINESCENT DOSEMETERS.

The aim of this study was to estimate the radiation effective doses for operators of nuclear moisture density gauges that are used in pavement construction in the road industry in Saudi Arabia from 2016 to 2019. The effective doses of 278 workers were estimated using thermoluminescent dosemeters (TLD-700). The analysis of the dosimetry data revealed that the mean annual effective dose for all workers averaged over the study period was 0.80 mSv, which falls below the recommended dose limits. About 68% of the pavement construction workers received annual effective doses of <1 mSv. All annual effective doses were below the recommended dose limits. While the annual effective mean dose of pavement construction workers in Saudi Arabia is not high, radiation protection in the country still needs to be further improved to protect such workers and to keep their annual radiation dose as low as reasonably achievable.

The Impact of the COVID-19 Pandemic on Medical Imaging Case Volumes in Aseer Region: A Retrospective Study.

COVID-19 has had a significant impact on global health systems. The aim of this study was to evaluate how imaging volumes and imaging types in radiology departments have been affected by the COVID-19 pandemic across different locations. METHODS: Imaging volumes in the Aseer region (in the south of Saudi Arabia) across main hospitals were reviewed retrospectively including all cases referred from different locations (outpatient, inpatient and emergency departments). Data for years 2019 and 2020 were compared. The mean monthly cases were compared using a t-test. RESULTS: The total imaging volumes in 2019 were 205,805 compared to 159,107 in 2020 with a 22.7% overall reduction. A substantial decline was observed in both the April to June and the July to September periods of approximately 42.9% and 44.4%, respectively. With respect to location, between April and June, the greatest decline was observed in outpatient departments (76% decline), followed by emergency departments (25% decline), and the least impact was observed in inpatient departments, with only 6.8% decline over the same period. According to modality type, the greatest decreases were reported in nuclear medicine, ultrasound, MRI, and mammography, by 100%, 76%, 74%, and 66%, respectively. Our results show a statistically significant (p-value ≤ 0.05) decrease of cases in 2020 compared to 2019, except for mammography procedures. CONCLUSION: There has been a significant decline in radiology volumes due to COVID-19. The overall reduction in radiology volumes was dependent on the stage/period of lockdown, location, and imaging modality.

Radiologic technologists in Saudi Arabia: Does long-term exposure to radiation increase the risk of hematological disorders?

OBJECTIVES: To determine the influence of prolonged exposure to radiation based on dosimeter readings on hematological parameters among radiologic technologists (RTs) in Saudi Arabia. METHODS: The study was specifically conducted on selected RTs with experience of more than 10 years and the highest thermoluminescent dosimeter (TLD) readings among all RTs in the Radiological Department, Sabya General Hospital, Ministry of Health, Saudi Arabia from August to October 2020. The RTs group was compared with a control group of non-irradiated participants. Blood samples were collected for hematological and coagulation profile evaluation. RESULTS: The acquired radiation dose analysis revealed that the average accumulated dose in 10 years is 7.6 mSv. The medians of prothrombin time (PT) and activated partial thromboplastin time (APTT) of the RTs group were significantly lower when compared to the control group. In addition, RTs group exhibited a significant reduction in neutrophil count and an elevation in lymphocyte count. CONCLUSION: Chronic exposure to radiation revealed a significant change in blood tests and may reflect an effect on RTs tissues, leading to serious health problems. However, further investigation in a large cohort to study the association between alteration in hematological parameters and chronic radiation exposure is required.

ANALYSIS OF HAND EXPOSURE AMONG NUCLEAR MEDICINE TECHNOLOGISTS IN SAUDI ARABIA.

The increase in the amount of radioactive materials administered to patients as well as the number of procedures performed has focused attention on the issue of radiation exposure to the hands of workers in nuclear medicine departments worldwide. The study aims to estimate the equivalent doses to the hands of individuals in nuclear medicine departments in Saudi. A cross-sectional analysis was conducted for 404 annual dose records in 16 nuclear medicine departments from 2016 to 2019. The monitoring of individual doses to the hands was performed using a Harshaw ring dosemeters. During the study period, the average annual equivalent doses per handled activity ranged from 0.21 to 0.41 µSv/GBq. The estimated annual activities of radiopharmaceuticals ranged from 2 to 930 MBq per exam. The hand dose averaged over the 4-year study period was determined to be 1.81 ± 0.25 mSv. The collective annual hand dose increased by 265% from 2016 to 2019.

A 5-YEAR RETROSPECTIVE ANALYSIS OF IONIZING RADIATION DOSE TO HYBRID OPERATING ROOM PERSONNEL IN SAUDI ARABIA.

The annual average effective dose (ED) for operating room personnel (ORP) in Saudi Arabia was estimated from the period of 2015-2019 using thermoluminescent dosemeters. A retrospective analysis was conducted on annual EDs for 7530 ORP working across 52 hospitals. These workers were only exposed to radiation in the operating room. The annual average ED over the period of 5 years was found to be 0.59 mSv with no incidence of a dose above the annual dose limit of 20 mSv. The maximum annual ED reported was 15 mSv for an operating room worker in 2019. More than 88% of the workers received an annual ED of <1 mSv. The study concluded that the work environment in hybrid operating rooms across Saudi Arabia is safe. However, it is always recommended that workers take every protective measure when dealing with ionization radiation.

OCCUPATIONAL DOSE ASSESSMENT FOR NUCLEAR MEDICINE AND RADIOTHERAPY TECHNOLOGISTS IN SAUDI ARABIA.

This study estimated the occupational radiation dose received by nuclear medicine and radiotherapy technologists in Saudi Arabia. A retrospective analysis of personal dosemetry data of 1243 nuclear medicine and radiotherapy technologists from 28 medical centers across Saudi Arabia from 2015 to 2019 was conducted. Thermoluminescent dosemeters were employed to monitor the occupational radiation dose. For the study period, the average annual values for nuclear medicine and radiotherapy technologists were found to be 1.22 mSv (SD = 1.00 mSv) and 0.73 mSv (SD = 0.40 mSv) for Hp(10) and 1.23 mSv (SD = 1.07 mSv) and 0.72 mSv (SD = 0.41 mSv) for Hp(0.07), respectively. The work routines of nuclear medicine technologists cause them to be exposed to higher radiation doses than radiotherapy technologists. The occupational doses for all technologists were found to be below the annual dose limits, which indicates satisfactory working conditions in terms of radiation protection.