Primary mucinous adenocarcinoma of the bladder with signet-ring cells: case report.

CONTEXT: Primary adenocarcinomas of the bladder are uncommon and usually occur by contiguity with or hematogenic dissemination of other adenocarcinomas such as colorectal, prostate and gynecological tract carcinomas. Mucinous and signet-ring cell histological patterns are even rarer and it is often difficult to morphologically distinguish them from metastatic colorectal adenocarcinoma. CASE REPORT: We present and discuss a rare case of primary mucinous adenocarcinoma of the bladder with signet-ring cells in a 57-year-old male patient. Other primary sites for the tumor had been excluded and, in the absence of digestive tract tumor and for confirmation that it was a primary bladder tumor, an immunohistochemistry study was performed.

Primary mucinous adenocarcinoma of the bladder with signet-ring cells: case report

CONTEXT: Primary adenocarcinomas of the bladder are uncommon and usually occur by contiguity with or hematogenic dissemination of other adenocarcinomas such as colorectal, prostate and gynecological tract carcinomas. Mucinous and signet-ring cell histological patterns are even rarer and it is often difficult to morphologically distinguish them from metastatic colorectal adenocarcinoma. CASE REPORT: We present and discuss a rare case of primary mucinous adenocarcinoma of the bladder with signet-ring cells in a 57-year-old male patient. Other primary sites for the tumor had been excluded and, in the absence of digestive tract tumor and for confirmation that it was a primary bladder tumor, an immunohistochemistry study was performed.

CONTEXTO: Adenocarcinomas vesicais primários são incomuns, o habitual é o comprometimento por contigüidade ou via hematogênica de outros adenocarcinomas como colorretal, próstata e trato ginecológico. O padrão histológico correspondente ao mucinoso e com células em anel de sinete é mais raro e, muitas vezes, há dificuldade em distingui-lo morfologicamente do adenocarcinoma colorretal metastático. RELATO DE CASO: Apresentamos e discutimos um caso de adenocarcinama mucinoso com células em anel de sinete primário da bexiga em um paciente masculino, de 57 anos. Foram excluídos outros sítios primários do tumor e, na ausência de tumor do trato digestivo e para confirmação de tumor vesical primário realizou-se estudo imunoistoquímico.

Mini-incisions by lombotomy or subcostal access in living kidney donors: a randomized trial comparing pain, safety, and quality of life.

OBJECTIVES: The aim of this study was to compare two mini-incision techniques and judge the impact on the quality of life, pain, and safety of living kidney donors. PATIENTS AND METHODS: From March through September 2003, a prospective randomized study with 60 donors had nephrectomy performed - 30 through a lombotomy and another 30 patients underwent subcostal mini-incisions. The same anesthetic procedure was used for both groups. All patients were evaluated from baseline (T0) to day 90 after surgery. Pain evaluation included visual analog scale (VAS) and drug usage. To assess quality of life (QOL), the questionnaire SF-36 was used and surgical outcomes were also checked. RESULTS: Sixty patients (41.6 +/- 8.9 yr old) were included in the protocol. Regarding incision length and blood loss, no statistical difference was observed. However, irrespective to the site of the mini-incision, patients with body mass index (BMI) higher than 25 kg/m(2) had significantly longer incision length as well as higher blood loss. There were no complications. No significant difference in tramadol or in pain perception was observed between groups. QOL was also not different between groups, however, there was a significant loss with subsequent return to baseline levels. CONCLUSION: The position of the mini-incision (lombotomy or subcostal) has no significant impact on surgical outcomes, pain perception, and QOL of living kidney donors. Mini-incision techniques represent fast and safe approaches to perform nephrectomy in the healthy population. Special care must be taken in obese patients in order to minimize surgical complications.

Correlaçao entre histologia, volume testicular e analise seminal em portadores de varicocele / Correlation among histology, testicular volume and semen analysis in patients with varicocele

Realizou-se a correçao cirurgica de varicocele e a biopsia testicular bilateral em 20 pacientes masculinos; avaliou-se a histologia espermatica, diametro e area tubular atraves da fotomicrografia. Dentre 20 pacientes, 11 apresentavam o testiculo esquerdo com volume pelo menos 25 por cento menor que o testiculo direito. Nos pacientes com menor volume testicular, nao houve diferença no diametro e area tubular, tendo porem menor numero de espermatides maduras por unidade tubular; esta diferença nao foi observada nos pacientes com igual volume testicular. Esses fatos nos permitem supor que a diminuiçao do volume testicular se faz as custas do espaço intersticial, provocando disfunçao das celulas de Leydig, que estao relacionadas com o numero de espermatides maduras, principal marcador da espermatogenese testicular

Correçäo da curvatura peniana com a operaçäo de Nesbit modificada / Correction of the penile curvature with the modified operation

Dezoito pacientes masculinos, com idade variando entre 1 ano e 7 meses e 72 anos foram submetidos `a correçäo cirúrgica de curvatura peniana pela técnica de Nesbit modificada. Destes 18 pacientes 8 apresentavam pênis curvo congênito, 7 doença de Peryronie, 2 hipospádia peniana distal, e 1 fibrose traumática. Esta técnica consiste na plicatura da túnica albugínea do corpo cavernoso com fio inabsorvível de polipropileno 4-0 (Prolene) na face contralateral da curvatura através de pontos invaginantes separados, sem excisäo de elipse de albugínea. Foi considerado como bom resultado daqueles casos em que houve retificaçäo completa de pênis, sem dor `a ereçäo; resultado regular aqueles com curvatura residual discreta ou dor `a ereçäo e mau resultado quando näo houve correçäo da curvatura peniana. Observamos que em 17 casos (94,4%), o resultado foi bom, e um paciente com curvatura peniana congênita evoluiu com mau resultado (5,5%). A técnica de Nesbit modificada mostrou ser um procedimento cirúrgico simples e näo traumática ao corpo cavernoso, com alto índice de sucesso para a correçäo da curvatura peniana

Necrose tardia de pelve renal em rim transplantado / Delayed necrosis of renal pelvis in transplanted kidney

Relata-se um caso de fístula urinária por necrose tardía da pelve renal em rim transplantado, que determinou sintomatologia clínica importante. Mostra-se a evoluçäo clínica e radiológica e discute-se a etiologia vascular desta patologia, sua incidência e a melhor conduta para a preservaçäo do enxerto

Processos infecciosos agudos do rim. / Acute infectious processes of the kidney

Os autores comentam os processos infecciosos renais e suas complicacoes, ressaltando a alteracao de sua etiofisopatogenia apos o advento dos antibioticos

Inflamacoes, infeccoes e processos vasculares do aparelho genital masculino. / Inflammation, infections and vascular processes of the male genital tract

Os autores fazem consideracoes sobre os processos infecciosos, inflamatorios e vasculares do aparelho genital masculino; abordando o quadro clinico, diagnostico e tratamento das epididimites, orquites, prostato-vesiculites, torcao de ducto espermatico e da hidatide de Morgagni, priapismo e parafimose