RESUMEN
We report a 9-year-old Saudi girl with dyskeratosis congenita. In addition to the known manifestations of this disease, she also had the additional features of tufts of hairs on the limbs, and an early onset of keratinized basal cell papillomas on her trunk.
Asunto(s)
Enfermedades de la Piel/congénito , Enfermedades de la Lengua/congénito , Niño , Femenino , Enfermedades del Cabello/congénito , Enfermedades del Cabello/patología , Humanos , Queratosis Seborreica/etiología , Enfermedades de la Piel/patología , Enfermedades de la Lengua/patologíaAsunto(s)
Liquen Plano/clasificación , Penfigoide Ampolloso/clasificación , Niño , Femenino , Humanos , Piel/patologíaRESUMEN
We report a male child with autosomal recessive epidermolysis bullosa simplex presenting at birth. The patient subsequently developed cutaneous atrophy, nail dystrophy, milia and alopecia. He had growth retardation and anaemia, but there were no other associated abnormalities. Electron microscopy showed epidermolytic cleavage. The family history indicated an autosomal recessive mode of inheritance.
Asunto(s)
Epidermólisis Ampollosa Simple/genética , Consanguinidad , Epidermólisis Ampollosa Simple/patología , Dermatosis Facial/genética , Dermatosis Facial/patología , Genes Recesivos , Humanos , Recién Nacido , Masculino , Enfermedades de la Uña/patologíaRESUMEN
Two patients with Sweet's syndrome are described, both of whom were treated with doxycycline 200 mg daily, and responded well to therapy. Doxycycline appears to be an effective alternative to corticosteroids for the treatment of Sweet's syndrome.
Asunto(s)
Doxiciclina/uso terapéutico , Síndrome de Sweet/tratamiento farmacológico , Adulto , Femenino , Humanos , Piel/patología , Síndrome de Sweet/patologíaRESUMEN
A case of subcorneal pustular dermatosis (SCPD), as a presenting feature in a patient with multiple myeloma, is described. This is the seventh case report of this association and the first from the Middle East. Five of these cases, including the present report, have been of the IgA paraprotein type, IgA intraepidermal deposits have been described in a few patients with SCPD associated with IgA paraproteinaemias but have not been detected in our patient.
