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Dakar Med ; 38(1): 49-54, 1993.
Artículo en Francés | MEDLINE | ID: mdl-7882849

RESUMEN

Hundred white Wistar rats have been used to evaluate the antihypertensive effects of entire seeds and decorticated, fermented seeds of a soudanian plant, Parkia biglobosa. The arterial blood pressure was measured by using bloody method in anesthizied animals. The Pham Huu Chanh method was used to determine type plant's antihypertensive activity. According to the results obtained, in both preparations, adequate doses decrease arterial blood pressure, diastolic more than systolic, but the effect of fermented seeds was more important than the entire seeds. In the two cases, the decrease in blood pressure is greated in hypertensive than in normotensive subjects, and the hypotension induced was well correlated with a bradycardia.


Asunto(s)
Hipertensión/tratamiento farmacológico , Plantas Medicinales , Animales , Presión Sanguínea/efectos de los fármacos , Relación Dosis-Respuesta a Droga , Masculino , Extractos Vegetales/uso terapéutico , Ratas , Ratas Wistar , Semillas , Senegal
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