RESUMEN
Secreted factors from pyroptotic cells can promote wound repair.
Asunto(s)
Piroptosis , Cicatrización de Heridas , Humanos , AnimalesRESUMEN
Highlights from the Science family of journals.
RESUMEN
Apoptosis of immature peripheral B cells may be due to a lack of survival signals rather than clonal deletion.
Asunto(s)
Linfocitos B , Humanos , Linfocitos B/metabolismo , Linfocitos B/inmunología , Linfocitos B/citología , Animales , Apoptosis , Transducción de SeñalRESUMEN
Prostaglandins in the tumor microenvironment block IL-2-induced expansion of killer T cells.
Asunto(s)
Interleucina-2 , Microambiente Tumoral , Interleucina-2/inmunología , Interleucina-2/metabolismo , Humanos , Microambiente Tumoral/inmunología , Animales , Neoplasias/inmunología , Neoplasias/metabolismo , Prostaglandinas/metabolismoRESUMEN
Highlights from the Science family of journals.
RESUMEN
Microglial lipid droplet accumulation leads to increased neurotoxicity in an APOE-dependent manner.
Asunto(s)
Enfermedad de Alzheimer , Humanos , Enfermedad de Alzheimer/tratamiento farmacológico , Lípidos , Apolipoproteínas E/genéticaRESUMEN
Highlights from the Science family of journals.
RESUMEN
Highlights from the Science family of journals.
RESUMEN
Highlights from the Science family of journals.
RESUMEN
ATP released by osteoblasts signals through the purinergic receptor P2RX4 to optimize plasma cell survival.
Asunto(s)
Osteoblastos , Células Plasmáticas , Supervivencia CelularRESUMEN
The DNA double-strand break sensor MRE11 is necessary to liberate cGAS and enable its activation by dsDNA.
Asunto(s)
Roturas del ADN de Doble Cadena , Nucleotidiltransferasas , Nucleotidiltransferasas/genéticaRESUMEN
The noncanonical caspase caspase-4 processes the pro form of IL-18 in response to LPS.
Asunto(s)
Caspasas , Lipopolisacáridos , Caspasa 1RESUMEN
Demyelination by microglia reduces the likelihood of axonal degeneration in a model of cytotoxic T cell-driven myelin perturbation.
Asunto(s)
Enfermedades Desmielinizantes , Humanos , Animales , Axones , Vaina de Mielina , Microglía , Modelos Animales de EnfermedadRESUMEN
Catecholamines associated with stress promote T cell exhaustion through the ß1-adrenergic receptor.
Asunto(s)
Catecolaminas , Linfocitos TRESUMEN
Highlights from the Science family of journals.
RESUMEN
Interferon-ε has antitumor activity and activates antitumor immunity in ovarian cancer in mice.
Asunto(s)
Interferones , Neoplasias Ováricas , Animales , Ratones , Femenino , Humanos , Neoplasias Ováricas/tratamiento farmacológicoRESUMEN
Loss of phosphatidylinositol transfer protein alpha underlies pancreatic ß cell failure.
Asunto(s)
Células Secretoras de Insulina , Células Secretoras de Insulina/metabolismoRESUMEN
Adrenergic receptor stimulation improves cancer immunotherapy in a range of immune-competent tumor models.
Asunto(s)
Acampada , Neoplasias , Humanos , Modelos Teóricos , Neoplasias/terapia , InmunoterapiaRESUMEN
Remodeling of neural circuits by glioma cells decreases patient survival.
Asunto(s)
Neoplasias Encefálicas , Glioma , Humanos , Glioma/genética , Transducción de Señal , Neuronas , Neoplasias Encefálicas/genéticaRESUMEN
STING activity in cancer cells prevents the progression of dormant metastasis.
