Biodegradable polylactic acid emulsion ink based on carbon nanotubes and silver for printed pressure sensors.

Investigating biodegradable and biocompatible materials for electronic applications can lead to tangible outcomes such as developing green-electronic devices and reducing the amount of e-waste. The proposed emulsion-based conducting ink formulation takes into consideration circular economy and green principles throughout the entire process, from the selection of materials to the production process. The ink is formulated using the biopolymer polylactic acid dissolved in a sustainable solvent mixed with water, along with conductive carbon nanotubes (CNTs) and silver flakes as fillers. Hybrid conductive fillers can lower the percolation threshold of the ink and the production costs, while maintaining excellent electrical properties. The coating formed after the deposition of the ink, undergoes isothermal treatment at different temperatures and durations to improve its adhesion and electrical properties. The coating's performance was evaluated by creating an eight-finger interdigitated sensor using a Voltera PCB printer. The sensor demonstrates exceptional performance when exposed to various loading and unloading pressures within the 0.2-500.0 kPa range. The results show a consistent correlation between the change in electrical resistance and the stress caused by the applied load. The ink is biodegradable in marine environments, which helps avoiding its accumulation in the ecosystem over time.

Investigating efficacy of colchicine plus phenolic monoterpenes fraction as a potential treatment for patients diagnosed with COVID-19: A randomized controlled parallel clinical trial.

Background: COVID-19 now is a serious concern for the world healthcare system. This study aimed to investigate possible therapeutic effect of colchicine and phenolic monoterpenes accompanied by standard care of treatment (SCT) in patients diagnosed with COVID-19. Methods: In this randomized controlled parallel clinical trial, a total number of 179 (of 200) patients with confirmed COVID-19 were enrolled according to the inclusion and exclusion criteria. The patients were allocated by simple randomization method into two groups control (receiving SCT with 71 patients) and intervention (receiving SCT plus colchicine and phenolic monoterpenes with 107 patients). The mortality ratio during hospitalization as well as a 2-week follow-up, ICU admission rate, and hospitalization duration were assessed as main outcomes. Results: The mortality ratio was 0.9% (1/108) and 8.45% (6/71) in the intervention and the control groups (p-value = 0.035) respectively, these ratios after a 14-day follow-up were 1.85% (2/108), and 9.85 (7/71) respectively (p-value = 0.031). Also, the ICU admission was significantly lower (p-value = 0.006) in the intervention group 2/108 (1.85%) compared with controls 10/71 (14.08%). Moreover, the duration of hospitalization followed a similar pattern to ICU admission with 4.17 ± 1.34 vs. 6.39 ± 2.59 days in the intervention and control groups respectively (p-value< 0.001). Furthermore, no significant side effect was found between the groups. Conclusion: According to the results, the combination of colchicine plus phenolic monoterpenes could be an additive treatment for the SCT. The authors strongly recommend further trials on this combination with other SCTs.

Hydrogen-Assisted Thermal Treatment of Electrode Materials for Electrochemical Double-Layer Capacitors.

The capacitance of electrode materials used in electrochemical double-layer capacitors (EDLCs) is currently limited by several factors, including inaccessible isolated micropores in high-surface area carbons, the finite density of states resulting in a quantum capacitance in series to Helmholtz double-layer capacitance, and the presence of surface impurities, such as functional groups and adsorbed species. To unlock the full potential of EDLC active materials and corresponding electrodes, several post-production treatments are commonly proposed to improve their capacitance and, thus, the energy density of the corresponding devices. In this work, we report a systematic study of the effect of a prototypical treatment, namely H2-assisted thermal treatment, on the chemical, structural, and thermal properties of activated carbon and corresponding electrodes. By combining multiple characterization techniques, we clarify the actual origins of the improvement of the performance (e.g., > +35% energy density for the investigated power densities in the 0.5-45 kW kg-1 range) of the EDLCs based on treated electrodes compared to the case based on the pristine electrodes. Contrary to previous works supporting a questionable graphitization of the activated carbon at temperatures <1000 °C, we found that a "surface graphitization" of the activated carbon, detected by spectroscopic analysis, is mainly associated with the desorption of surface contaminants. The elimination of surface impurities, including adsorbed species, improves the surface capacitance of the activated carbon (CsurfAC) by +37.1 and +36.3% at specific currents of 1 and 10 A g-1, respectively. Despite the presence of slight densification of the activated carbon upon the thermal treatment, the latter still improves the cell gravimetric capacitance normalized on the mass of the activated carbon only (CgAC), e.g., + 28% at 1 A g-1. Besides, our holistic approach identifies the change in the active material and binder contents as a concomitant cause of the increase of cell gravimetric capacitance (Cg), accounting for the mass of all of the electrode materials measured for treated electrodes compared to pristine ones. Overall, this study provides new insights into the relationship between the modifications of the electrode materials induced by H2-assisted thermal treatments and the performance of the resulting EDLCs.

The correlation between the micelle morphology of surface-active ionic liquids with self-assembly and thermodynamic characteristics: coarse-grained MD simulation and experiment.

Surface-active ionic liquids (SAILs) show great promise as novel green solvents due to their low vapor pressure, high thermal stability, high electrical conductivity, and bio-friendly nature to replace traditional volatile organic solvents in industrial processes. In the present work, the combination of coarse-grained (CG) molecular dynamics (MD) simulations with conductivity measurements was employed to explain the correlation between the micelle morphology and physicochemical and thermodynamic properties of self-assembly. A homologous series of SAIL molecules, 1-n-alkyl-3-methylimidazolium bromide [Cnmim][Br] (n = 4, 6, 8, 10, and 12), were chosen at various concentrations to shed light on this issue. Simultaneously two factors of concentration and alkyl chain length affected the morphology to control the physical and thermodynamic features. Moreover, the nature of the headgroup for two SAILs with the longest alkyl chain was assessed by shifting from imidazolium into ammonium. First, the critical micelle concentration (CMC), the degree of counterion dissociation of micelles, and the standard Gibbs energy of micellization of SAILs were determined using conductivity data. The micelle morphology such as the aggregation number, micelle radius, and moment of inertia was computed before, around, and after the CMC by MD simulation. Simulated results in accordance with the experimental measurements provide a quantitative understanding of the micellar properties. Increasing the alkyl chain length was associated with a non-spherical bigger micelle while the ammonium-based surfactant with a lower repulsion between neighboring monomers in micelles induced bigger and more spherical aggregates. Raising the SAIL concentration did not considerably influence the sphericity of the micelle except for the SAIL with the longest tail. The umbrella sampling method calculated the potential of mean force (PMF) for pulling a monomer of SAIL from a pre-assembled micelle into the solution. The dissociation energy of a SAIL monomer from a micelle increased with the tail length or with shifting into the ammonium head group and was substantially influenced by micelle morphology. Comparison between a sphere micelle with an oval one demonstrated that the dissociation of a SAIL monomer from a non-spherical shape needed a higher amount of energy. An improved understanding of how the shape of the SAIL micelles controls the physicochemical properties and stability helps to extend their application to different chemical processes.

Electrocatalytic Performance of MnMoO4-rGO Nano-Electrocatalyst for Methanol and Ethanol Oxidation.

Today, finding low-cost electro-catalysts for methanol and ethanol oxidation with high performance and stability is one of the new research topics. A nanocatalyst based on metal oxides in the form of MnMoO4 was synthesized by a hydrothermal method for methanol (MOR) and ethanol (EOR) oxidation reactions. Adding reduced graphene oxide (rGO) to the catalyst structure improved the electrocatalytic activity of MnMoO4 for the oxidation processes. The crystal structure and morphology of the MnMoO4 and MnMoO4-rGO nanocatalysts were investigated by physical analyses such as scanning electron microscopy and X-ray diffraction. Their abilities for MOR and EOR processes in an alkaline medium were evaluated by performing electrochemical tests such as cyclic voltammetry, chronoamperometry, and electrochemical impedance spectroscopy. MnMoO4-rGO showed oxidation current densities of 60.59 and 25.39 mA/cm2 and peak potentials of 0.62 and 0.67 V in MOR and EOR processes (at a scan rate of 40 mV/s), respectively. Moreover, stabilities of 91.7% in MOR and 88.6% in EOR processes were obtained from the chronoamperometry analysis within 6 h. All these features make MnMoO4-rGO a promising electrochemical catalyst for the oxidation of alcohols.

Synergistic effects of binary surfactant mixtures in the adsorption of diclofenac sodium drug from aqueous solution by modified zeolite.

In this paper, the surfactant-modified clinoptilolite zeolite (with two methods) were used to remove diclofenac sodium (DFS) as a widely used drug in an aqueous solution. Clinoptilolite was modified by using pure cationic surfactant (cetyltrimethylammonium chloride, CTAC) and the mixed surfactants of CTAC + Triton-X100 (TX100). In the new approach, the synergistic effects between CTAC and TX100 were determined by surface tension measurements in different mole fractions and the optimum ratio (y1 ≈ 0.8) was identified with the maximum synergism. According to the mole fraction of this composition, the surface of clinoptilolite was modified by mixed surfactants (MSMZ) for the adsorption of DFS and then results compared with modified zeolite with pure cationic surfactant (SMZ). The raw and modified (SMZ and MSMZ) zeolites were characterized by Fourier transform infrared spectroscopy (FT-IR), BET analysis, the scanning electron microscopy (SEM) images, Zeta potential and X-ray. The experimental data of adsorption in equilibrium conditions were also analyzed using different adsorption isotherm models (Langmuir, Freundlich, Hill, Khan, Sips, Redlich-Peterson and Toth) in non-linear forms, and finally, the best model consistent with experimental data is determined (SMZ:Sips and MSMZ:Toth). According to the best isotherm model, the amount of absorption capacity in MSMZ was obtained almost 57% higher than SMZ. In addition, the kinetic adsorption data were correlated with eight various models in order to selection the best model for these systems. The kinetic adsorption data were well described by fractal-like pseudo-first-order (FL-PFO) and IKL models for SMZ and MSMZ adsorbents, respectively. Eight error functions were used to estimate the best fitted isotherm and kinetic models.

Predicting the aggregation number of cationic surfactants based on ANN-QSAR modeling approaches: understanding the impact of molecular descriptors on aggregation numbers.

In this work, a quantitative structure-activity relationship (QSAR) study is performed on some cationic surfactants to evaluate the relationship between the molecular structures of the compounds with their aggregation numbers (AGGNs) in aqueous solution at 25 °C. An artificial neural network (ANN) model is combined with the QSAR study to predict the aggregation number of the surfactants. In the ANN analysis, four out of more than 3000 molecular descriptors were used as input variables, and the complete set of 41 cationic surfactants was randomly divided into a training set of 29, a test set of 6, and a validation set of 6 molecules. After that, a multiple linear regression (MLR) analysis was utilized to build a linear model using the same descriptors and the results were compared statistically with those of the ANN analysis. The square of the correlation coefficient (R 2) and root mean square error (RMSE) of the ANN and MLR models (for the whole data set) were 0.9392, 7.84, and 0.5010, 22.52, respectively. The results of the comparison revealed the efficiency of ANN in detecting a correlation between the molecular structure of surfactants and their AGGN values with a high predictive power due to the non-linearity in the studied data. Based on the ANN algorithm, the relative importance of the selected descriptors was computed and arranged in the following descending order: H-047 > ESpm12x > JGI6> Mor20p. Then, the QSAR data was interpreted and the impact of each descriptor on the AGGNs of the molecules were thoroughly discussed. The results showed there is a correlation between each selected descriptor and the AGGN values of the surfactants.

Biopolymer-based electrospun fibers in electrochemical devices: versatile platform for energy, environment, and health monitoring.

Electrochemical power tools are regarded as essential keys in a world that is becoming increasingly reliant on fossil fuels in order to meet the challenges of rapidly depleting fossil fuel supplies. Additionally, due to the industrialization of societies and the growth of diseases, the need for sensitive, reliable, inexpensive, and portable sensors and biosensors for noninvasive monitoring of human health and environmental pollution is felt more than ever before. In recent decades, electrospun fibers have emerged as promising candidates for the fabrication of highly efficient electrochemical devices, such as actuators, batteries, fuel cells, supercapacitors, and biosensors. Meanwhile, the use of synthetic polymers in the fabrication of versatile electrochemical devices has raised environmental concerns, leading to an increase in the quest for natural polymers. Natural polymers are primarily derived from microorganisms and plants. Despite the challenges of processing bio-based electrospun fibers, employing natural nanofibers in the fabrication of electrochemical devices has garnered tremendous attention in recent years. Here, various natural polymers and the strategies employed to fabricate various electrospun biopolymers are briefly covered. The recent advances and research strategies used to apply the bio-based electrospun membranes in different electrochemical devices are carefully summarized, along with the scopes in various advanced technologies. A comprehensive and critical discussion about the use of biopolymer-based electrospun fibers as the potential alternative to non-renewable ones in future technologies is briefly highlighted. This review will serve as a field opening platform for using different biopolymer-based electrospun fibers to advance the electrochemical device-based renewable and sustainable technologies, which will be of high interest to a large community. Accordingly, future studies should focus on feasible and cost-effective extraction of biopolymers from natural resources as well as fabrication of high-performance nanofibrous biopolymer-based components applicable in various electrochemical devices.

Functionalized Metallic 2D Transition Metal Dichalcogenide-Based Solid-State Electrolyte for Flexible All-Solid-State Supercapacitors.

Highly efficient and durable flexible solid-state supercapacitors (FSSSCs) are emerging as low-cost devices for portable and wearable electronics due to the elimination of leakage of toxic/corrosive liquid electrolytes and their capability to withstand elevated mechanical stresses. Nevertheless, the spread of FSSSCs requires the development of durable and highly conductive solid-state electrolytes, whose electrochemical characteristics must be competitive with those of traditional liquid electrolytes. Here, we propose an innovative composite solid-state electrolyte prepared by incorporating metallic two-dimensional group-5 transition metal dichalcogenides, namely, liquid-phase exfoliated functionalized niobium disulfide (f-NbS2) nanoflakes, into a sulfonated poly(ether ether ketone) (SPEEK) polymeric matrix. The terminal sulfonate groups in f-NbS2 nanoflakes interact with the sulfonic acid groups of SPEEK by forming a robust hydrogen bonding network. Consequently, the composite solid-state electrolyte is mechanically/dimensionally stable even at a degree of sulfonation of SPEEK as high as 70.2%. At this degree of sulfonation, the mechanical strength is 38.3 MPa, and thanks to an efficient proton transport through the Grotthuss mechanism, the proton conductivity is as high as 94.4 mS cm-1 at room temperature. To elucidate the importance of the interaction between the electrode materials (including active materials and binders) and the solid-state electrolyte, solid-state supercapacitors were produced using SPEEK and poly(vinylidene fluoride) as proton conducting and nonconducting binders, respectively. The use of our solid-state electrolyte in combination with proton-conducting SPEEK binder and carbonaceous electrode materials (mixture of activated carbon, single/few-layer graphene, and carbon black) results in a solid-state supercapacitor with a specific capacitance of 116 F g-1 at 0.02 A g-1, optimal rate capability (76 F g-1 at 10 A g-1), and electrochemical stability during galvanostatic charge/discharge cycling and folding/bending stresses.

Recent Advances in the Application of Covalent Organic Frameworks in Extraction: A Review.

Covalent organic frameworks (COFs) are a class of emerging materials that are synthesized based on the covalent bonds between different building blocks. COFs possess unique attributes in terms of high porosity, tunable structure, ordered channels, easy modification, large surface area, and great physical and chemical stability. Due to these features, COFs have been extensively applied as adsorbents in various extraction modes. Enhanced extraction performance could be reached with modified COFs, where COFs are presented as composites with other materials including nanomaterials, carbon and its derivatives, silica, metal-organic frameworks, molecularly imprinted polymers, etc. This review article describes the recent advances, developments, and applications of COF-based materials being utilized as adsorbents in the extraction methods. The COFs, their properties, their synthesis approaches as well as their composite structures are reviewed. Most importantly, suggested mechanisms for the extraction of analyte(s) by COF-based materials are also discussed. Finally, the current challenges and future prospects of COF-based materials in extraction methods are summarized and considered in order to provide more insights into this field.

Polyoxometalate-based materials in extraction, and electrochemical and optical detection methods: A review.

Polyoxometalates (POMs) as metal-oxide anions have exceptional properties like high negative charges, remarkable redox abilities, unique ligand properties and availability of organic grafting. Moreover, the amenability of POMs to modification with different materials makes them suitable as precursors to further obtain new composites. Due to their unique attributes, POMs and their composites have been utilized as adsorbents, electrodes and catalysts in extraction, and electrochemical and optical detection methods, respectively. A survey of the recent progress and developments of POM-based materials in these methods is therefore desirable, and should be of great interest. In this review article, POM-based materials, their properties as well as their identification methods, and analytical applications as adsorbents, electrodes and catalysts, and corresponding mechanisms of action, where relevant, are reviewed. Some current issues of the utilization of these materials and their future prospects in analytical chemistry are discussed.

Sulfonated NbS2-based proton-exchange membranes for vanadium redox flow batteries.

In this work, novel proton-exchange membranes (PEMs) based on sulfonated poly(ether ether ketone) (SPEEK) and two-dimensional (2D) sulfonated niobium disulphide (S-NbS2) nanoflakes are synthesized by a solution-casting method and used in vanadium redox flow batteries (VRFBs). The NbS2 nanoflakes are produced by liquid-phase exfoliation of their bulk counterpart and chemically functionalized with terminal sulfonate groups to improve dimensional and chemical stabilities, proton conductivity (σ) and fuel barrier properties of the as-produced membranes. The addition of S-NbS2 nanoflakes to SPEEK decreases the vanadium ion permeability from 5.42 × 10-7 to 2.34 × 10-7 cm2 min-1. Meanwhile, it increases the membrane σ and selectivity up to 94.35 mS cm-2 and 40.32 × 104 S min cm-3, respectively. The cell assembled with the optimized membrane incorporating 2.5 wt% of S-NbS2 nanoflakes (SPEEK:2.5% S-NbS2) exhibits high efficiency metrics, i.e., coulombic efficiency between 98.7 and 99.0%, voltage efficiency between 90.2 and 73.2% and energy efficiency between 89.3 and 72.8% within the current density range of 100-300 mA cm-2, delivering a maximum power density of 0.83 W cm-2 at a current density of 870 mA cm-2. The SPEEK:2.5% S-NbS2 membrane-based VRFBs show a stable behavior over 200 cycles at 200 mA cm-2. This study opens up an effective avenue for the production of advanced SPEEK-based membranes for VRFBs.

Applications of covalent organic frameworks and their composites in the extraction of pesticides from different samples.

Pesticides are used extensively in a wide range of applications and due to their high rate of consumption, they are ubiquitous in the different media and samples like environment, water sources, air, soil, biological materials, wastes (liquids, solids or sludges), vegetables and fruits, where they can persist for long periods. Pesticides often have hazardous side effects and can cause a range of harmful diseases like Parkinson, Alzheimer, asthma, depression and anxiety, cancer, etc, even at low concentrations. To this end, extraction, pre-concentration and determination of pesticides from various samples presents significant challenges caused by sample complexity and the low concentrations of them in many samples. Often, direct extraction and determination of pesticides are impossible due to their low concentrations and the complexity of samples. The main goals of sample preparation are removing interfering species, pre-concentrating target analyte/s and converting the analytes into more stable forms (when needed). The most popular approach is solid-phase extraction due to its simplicity, efficiency, ease of operation and low cost. This method is based on using a wide variety of materials, among which covalent organic frameworks (COFs) can be identified as an emerging class of highly versatile materials exhibiting advantageous properties, such as a porous and crystalline structure, pre-designable structure, high physical and chemical stability, ease of modification, high surface area and high adsorption capacity. The present review will cover recent developments in synthesis and applications of COFs and their composites for extraction of pesticides, different synthesis approaches of COFs, possible mechanisms for interaction of COFs-based adsorbents with pesticides and finally, future prospects and challenges in the fabrication and utilization of COFs and their composites for extraction of pesticides.

Increasing Antioxidant Activity in Food Waste Extracts by ß-Glucosidase.

Research background: Food by-products such as onion peels and olive leaves are rich in bioactive compounds applicable as natural and low-cost sources of antioxidants. Still, these compounds mainly exist in glycosylated form. Often, hydrolysis of glycoside compounds increases their antioxidant activity and health benefits. However, not many studies have been done concerning the ß-glucosidase effect, specifically from Aspergillus niger, on glycosylated compounds within these by-products. Also, changes in the antioxidant activity of the mentioned by-products under the effect of ß-glucosidase have not been reported yet. Therefore, this study considers the effect of A. niger ß-glucosidase on glucoside compounds and the antioxidant activity of onion peel and olive leaf extracts. Experimental approach: The antioxidant activity of the extracts was determined by 1,1-diphenyl-2-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP) assays. Also, glucose, total phenolic and flavonoid contents were measured. Moreover, TLC and HPLC analyses were performed before and after the enzymatic hydrolysis. Results and conclusions: The obtained results showed an increase in the extract antioxidant activity after treatment. Also, ß-glucosidase increased the glucose content of the extracts. The thin layer chromatography (TLC) and high-performance liquid chromatography (HPLC) results showed the ß-glucosidase efficacy to hydrolyze quercetin glucosides in onion peel extract, and the quercetin concentration increased from (0.48±0.04) mg/mL in the untreated extract to (1.26±0.03) mg/mL in the treated extract (0.5% m/V) after 3 h of enzymatic hydrolysis at 45 °C. Also, the content of quercetin-3-O-glucoside increased considerably from (1.8±0.1) to (54±9) µg/mL following the enzyme treatment. Moreover, oleuropein in olive leaf extract (1% m/V) was hydrolyzed completely from (0.382±0.016) to 0 mg/mL by ß-glucosidase for 24 h at 50 °C. Novelty and scientific contribution: This study showed that A. niger ß-glucosidase, as a stable enzyme, hydrolyzed quercetin and oleuropein glycosides in onion peel and olive leaf extracts. Thus, A. niger ß-glucosidase is a good candidate for processing the food waste and extracting valuable bioactive compounds. Also, the treated extracts with higher antioxidant and biological activity, and without bitter taste can be applicable as potent, natural and cost-effective antioxidants in the food industry.

Carbon nanomaterials as emerging nanotherapeutic platforms to tackle the rising tide of cancer - A review.

Cancer has become one of the main reasons for human death in recent years. Around 18 million new cancer cases and approximately 9.6 million deaths from cancer reported in 2018, and the annual number of cancer cases will have increased to 22 million in the next two decades. These alarming facts have rekindled researchers' attention to develop and apply different approaches for cancer therapy. Unfortunately, most of the applied methods for cancer therapy not only have adverse side effects like toxicity and damage of healthy cells but also have a short lifetime. To this end, introducing innovative and effective methods for cancer therapy is vital and necessary. Among different potential materials, carbon nanomaterials can cope with the rising threats of cancer. Due to unique physicochemical properties of different carbon nanomaterials including carbon, fullerene, carbon dots, graphite, single-walled carbon nanotube and multi-walled carbon nanotubes, they exhibit possibilities to address the drawbacks for cancer therapy. Carbon nanomaterials are prodigious materials due to their ability in drug delivery or remedial of small molecules. Functionalization of carbon nanomaterials can improve the cancer therapy process and decrement the side effects. These exceptional traits make carbon nanomaterials as versatile and prevalent materials for application in cancer therapy. This article spotlights the recent findings in cancer therapy using carbon nanomaterials (2015-till now). Different types of carbon nanomaterials and their utilization in cancer therapy were highlighted. The plausible mechanisms for the action of carbon nanomaterials in cancer therapy were elucidated and the advantages and disadvantages of each material were also illustrated. Finally, the current problems and future challenges for cancer therapy based on carbon nanomaterials were discussed.

Recent advances in covalent organic frameworks for cancer diagnosis and therapy.

In recent years, the number of patients diagnosed with cancer has been soaring. Therefore, the design, development, and implementation of new approaches for the diagnosis and therapy of different types of cancers have attracted an increasing amount of attention. To date, different methods have been used for cancer diagnosis and therapy with main drawbacks in terms of severe side effects, e.g., damage to healthy cells, development of drug resistance and tumor recurrence. Therefore, there is an urgent need for the introduction and application of innovative methods. Covalent organic frameworks (COFs) are versatile materials with excellent properties in terms of biocompatibility, porous and crystalline structure, and easy functionalization. The porous structure and organic monomers in COFs allow them to load different therapeutic drugs and/or functional species efficiently. These promising properties make COFs ideal candidates for medical application, especially in cancer diagnosis and therapy. To date, many studies have focused on the design and synthesis of novel COFs while their application as diagnostic and therapeutic materials remains less understood. In this review, different synthesis and functionalization approaches of COFs were summarized. In particular, cancer diagnosis and therapy based on COFs were investigated and the advantages and limitations of each method were discussed. Most importantly, the mechanism for cancer therapy of COFs and fundamental challenges and perspectives for the application of COFs in cancer theranostics were assessed.

Microplastic contaminants in the aqueous environment, fate, toxicity consequences, and remediation strategies.

Microplastic is a fragmented plastic part that emerges as a potential marine and terrestrial contaminant. The microplastic wastes in marine and soil environments cause severe problems in living systems. Microplastic wastes have been linked to various health problems, including reproductive harm and obesity, plus issues such as organ problems and developmental delays in children. Recycling plastic/microplastics from the environment is very low, so remediating these polymers after their utilization is of paramount concern. The microplastic causes severe toxic effects and contaminates the environment. Microplastic affects marine life, microorganism in soil, soil enzymes, plants system, and physicochemical properties. Ecotoxicology of the microplastic raised many questions about its use and development from the environment. Various physicochemical and microbial technologies have been developed for their remediation from the environment. The microplastic effects are linked with its concentration, size, and shape in contaminated environments. Microplastic is able to sorb the inorganic and organic contaminants and affect their fate into the contaminated sites. Microbial technology is considered safer for the remediation of the microplastics via its unique metabolic machinery. Bioplastic is regarded as safer and eco-friendly as compared to plastics. The review article explored an in-depth understanding of the microplastic, its fate, toxicity to the environment, and robust remediation strategies.

Mitigation of environmentally hazardous pollutants by magnetically responsive composite materials.

At present, environmental contamination has become an emerging issue among researchers. These facts are due to the adverse impacts of an alarming number of recalcitrant contaminants that can affect both humans and animals. There is an urgent need to develop eco-friendly approaches to mitigate the effects of toxic pollutants from the environment. Magnetically responsive composite-based sorbents are very interesting and popular materials for pollutant abatement owing to the high specific surface area, superior adsorption capacity, and magnetic properties, which make their easy separation from sample solution/media. In this review article, we discuss various synthesis approaches, key physicochemical properties, and applications of magnetic composites for pollutant removal. Current gaps for coping with contamination are identified, and a comprehensive outlook in pollutant treatment using magnetic composites is outlined. This study unveils new horizons to researches for better understanding the properties of magnetically-composite-based sorbents and their application in environmental remediation.

Serum Eicosapentaenoic and Arachidonic Acids Concentration and Cognitive Function in Patients With Coronary Artery Disease.

INTRODUCTION: Recent studies have shown that Polyunsaturated Fatty Acids (PUFAs), including Eicosapentaenoic Acid (EPA), and Arachidonic Acid (AA), are associated with cognitive functions in patients with Coronary Artery Disease (CAD). Nevertheless, controversial results have been reported, too. The current study aimed to clarify the association of serum EPA and AA levels with cognitive decline in an Iranian sample with CAD. METHODS: We evaluated cognitive function with the Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA), in relation to serum levels of EPA and AA, in 179 CAD patients. The associations between the MMSE and MoCA scores and the other demographic parameters were evaluated. RESULTS: Patients with CAD generally had mild cognitive impairment. But we could not find any significant correlation between PUFAs and cognitive function. However, BMI was associated with EPA/MoCA; age was associated with MMSE/MoCA and BMI. Finally, the correlation between sex and MMSE/MoCA was significant. CONCLUSION: Subjects generally had mild cognitive impairment, but we could not find any significant correlation between serum EPA and AA levels with cognitive function.

Chitosan-based hybrid materials for adsorptive removal of dyes and underlying interaction mechanisms.

Environmental pollution by dyes molecules has become a subject of intensive research in recent years due to their hazardous effects on human health, organisms, and animals. Effective treatment and removal of dye molecules from the environmental matrices and water sources are of supreme concern. The deployment of cheap, safe, green, sustainable, and eco-friendly materials to remove these pollutants from water is the main challenge during the last decades. Chitosan and its derivatives/composites, as a cheap, easily available, and environmentally friendly sorbent, have attracted increasing attention for the removal of dye molecules. This review article focuses on the application of chitosan and chitosan-based smart adsorbents for the removal of dyes. Recent methods for the preparation of chitosan-based composites and their application in the removal of dyes are discussed. Moreover, the possible mechanisms for the interaction of chitosan and chitosan-based adsorbents with dyes molecules were evaluated. Finally, future prospects of using chitosan as an adsorbent for the removal of dye molecules are directed.