1.
Org Lett
; 21(10): 3481-3484, 2019 05 17.
Artículo
en Inglés
| MEDLINE
| ID: mdl-30908052
RESUMEN
Asymmetric synthesis of 1-substituted 2,6-diazaspiro[3.3]heptane is described. This methodology affords excellent yields (up to 89%) and high diastereomeric ratios ( dr up to 98:2) and delivers differentially protected amines within the products.