RESUMEN
BACKGROUND: To investigate the clinical application and effect of laparoscopic partial nephrectomy with renal artery branch occlusion in the treatment of early renal tumors. METHODS: A retrospective analysis was conducted on the clinical data of 15 cases of renal tumor patients who underwent partial nephrectomy by laparoscopic selective renal artery branch occlusion in our department from January 2017 to January 2018. Nine male patients and 6 female patients were aged 46 to 65âyears, with an average age of 54.3â±â7.2âyears. The diameters of tumors were 2.2 to 4.0âcm, with an average of 3.3â±â0.7âcm. There are 10 tumors locating on the left side and 5 on the right side. Preoperative renal glomerular filtration rate (GFR) were 77.3 to 61.9âmL/min with an average of 47.6â±â7.5âmL/min. All patients' diseased kidneys underwent renal computer tomography angiography examination before surgery. And the diseased kidney underwent reexamination of renal GFR. The operation time, renal artery branch occlusion time, intraoperative blood loss, postoperative hospital stay, changes of renal function, and complications were evaluated. RESULTS: All surgery were completed successfully, the surgery time was 136.7â±â15.2âmin, intraoperative renal artery branch occlusion time was 21.3â±â4.5âmin, the intraoperative blood loss was 223.3â±â69.5âmL, the postoperative hospital stay was 6.5â±â1.7âdays, and the postoperative 1-month GFR was 49.5â±â6.6âmL/min. There was no significant difference between the renal GFR before and after surgery (Pâ>â.05). There was no blood transfusion and transfer open surgery cases. The patients were followed up for 3 to 15âmonths without complications. CONCLUSIONS: Partial nephrectomy with selective renal artery branch occlusion by laparoscopy is a safe, feasible, and effective method for the treatment of early renal cancer. It makes good use of the technical advantages of clear operation field and fine operation of laparoscopic surgery, avoids the heat ischemia process of the whole kidney, and can better protect the renal function.
Asunto(s)
Embolización Terapéutica/métodos , Neoplasias Renales , Laparoscopía , Nefrectomía , Arteria Renal , China/epidemiología , Angiografía por Tomografía Computarizada/métodos , Intervención Médica Temprana/métodos , Femenino , Humanos , Pruebas de Función Renal/métodos , Neoplasias Renales/irrigación sanguínea , Neoplasias Renales/patología , Neoplasias Renales/cirugía , Laparoscopía/efectos adversos , Laparoscopía/métodos , Laparoscopía/estadística & datos numéricos , Masculino , Persona de Mediana Edad , Estadificación de Neoplasias , Nefrectomía/efectos adversos , Nefrectomía/métodos , Evaluación de Procesos y Resultados en Atención de Salud , Cuidados Posoperatorios/métodos , Arteria Renal/diagnóstico por imagen , Arteria Renal/cirugía , Carga TumoralRESUMEN
OBJECTIVE: To sum up the clinical experience in the management of benign prostatic hyperplasia (BPH) with the prostate weighing over 80 ml by transurethral resection of the prostate (TURP) combined with 2 µm continuous-wave laser vaporesection (LVR). METHODS: We retrospectively analyzed the clinical effects of TURP combined with 2 µm LVR in the treatment of 46 cases of BPH with the prostate volume > 80 ml. RESULTS: All the operations were successfully accomplished. The operation time and intraoperative blood loss were (112.0 ± 20.0) min (range 86-176 min) and (77.9 ± 25.9) ml (range 50-200 ml), respectively. The catheters were withdrawn at 7 days after surgery. Transient urinary incontinence occurred in 6 cases and secondary hemorrhage was found in 2 postoperatively. Six-month follow-up revealed no urethral stricture or other complications. Compared with the baseline, the international prostate symptom score (IPSS) was significantly decreased at 6 months after operation (26.3 ± 1.8 vs 11.6 ± 1.7, P <0.05), and so were the quality of life (QOL) score (5.3 ± 0.7 vs 1.3 ± 1.1, P <0.05) and post-void residual urine (PVR) ([115.5 ± 55.6] ml vs [19.9 ± 11.6] ml, P <0.05). However, the maximum urinary flow rate (Qmax) was remarkably increased from (4.1 ± 2.6) ml/s to (16.2 ± 1.7) ml/s (P <0.05). CONCLUSION: TURP combined with 2 µm LVR is safe and effective for the treatment of BPH with the prostate volume >80 ml.