Optimizing long-term joint health in the treatment of hemophilia.

INTRODUCTION: The improved quality of care and increased drug availability have shifted the goal of treating people with hemophilia from life-threatening bleeding prevention to joint health preservation and quality of life amelioration. Many tools are now available to the clinician in order to optimize the management of hemophilic arthropathy. AREAS COVERED: This paper reviews the pivotal role of ultrasound evaluation in early detection of joint bleeding and differential diagnosis of joint pain, with a focus on the feasibility of a long-term monitoring of joint health through the use of artificial intelligence and telemedicine. The literature search methodology included using keywords to search in PubMed and Google Scholar, and articles used were screened by the coauthors of this review. EXPERT OPINION: Joint ultrasound is a practical point-of-care tool with many advantages, including immediate correlation between imaging and clinical presentation, and dynamic evaluation of multiple joints. The potential of telemedicine care, coupled with a point-of-care detection device assisted by artificial intelligence, holds promises for even earlier diagnosis and treatment of joint bleeding. A multidisciplinary approach including early intervention by physical medicine and rehabilitation (PMR) physicians and physiotherapists is crucial to ensure the best possible quality of life for the patient.

Enabling Green Crowdsourced Social Delivery Networks in Urban Communities.

With the ever-increasing popularity of wearable devices, data on the time and location of popular walking, running, and bicycling routes is expansive and growing rapidly. These data are currently used primarily for route discovery and mobile context awareness, as it provides precise and updated information about urban dynamics. We leverage these data to build ad hoc transportation flows, and we present a novel model that creates delivery networks from these zero-emission transportation flows. We evaluate the model using data from two popular datasets, and our results indicate that such networks are indeed possible, and can help reduce traffic, emissions, and delivery times. Moreover, we demonstrate how our results can be consistently reproduced in different cities with different subsets of carriers. We then extend our work into predicting routes of vehicles, hence possible delivery flows, based on the traces history. We conclude this paper by laying the groundwork for a future real-world study.

Performance evaluation of hybrid crowdsensing systems with stateful CrowdSenSim 2.0 simulator.

Mobile crowdsensing (MCS) has become a popular paradigm for data collection in urban environments. In MCS systems, a crowd supplies sensing information for monitoring phenomena through mobile devices. Depending on the degree of involvement of users, MCS systems can be participatory, opportunistic or hybrid, which combines strengths of above approaches. Typically, a large number of participants is required to make a sensing campaign successful which makes impractical to build and deploy large testbeds to assess the performance of MCS phases like data collection, user recruitment, and evaluating the quality of information. Simulations offer a valid alternative. In this paper, we focus on hybrid MCS and extend CrowdSenSim 2.0 in order to support such systems. Specifically, we propose an algorithm for efficient re-route users that would offer opportunistic contribution towards the location of sensitive MCS tasks that require participatory-type of sensing contribution. We implement such design in CrowdSenSim 2.0, which by itself extends the original CrowdSenSim by featuring a stateful approach to support algorithms where the chronological order of events matters, extensions of the architectural modules, including an additional system to model urban environments, code refactoring, and parallel execution of algorithms.