[Effect of long-term ambulatory hypotensive treatment on the structural and functional status of the myocardium]. / Vliianie dlitel'nogo ambulatornogo gipotenzivnogo lecheniia na strukturno-funktsional'noe sostoianie miokarda.

Changes in myocardial function and the possibility of a regression of left-ventricular hypertrophy were examined in patients with stable hypertension during a year of effective hypotensive treatment. Ninety-seven patients with essential hypertension, stage IIB (by Myasnikov's classification) and aged 35 to 56 years, were studied. Echography was conducted before the onset of treatment and after one year of regular hypotensive therapy. A marked hypotensive effect was noted in the course of treatment. Left-ventricular myocardial weight declined in 69% of patients, remained unchanged in 18.6% and increased in 12.4% despite the hypotensive effect of treatment. The reduction of left-ventricular hypertrophy was associated with no basic changes of myocardial pump function or contractility.

[Characteristics of left ventricular hypertrophy in patients with different forms of arterial hypertension based on echocardiographic data]. / Kharakteristika gipertrofii levogo zheludka u bol'nykh s razlichnymi formami arterial'noi gipertonii po dannym ékhokardiografii.

Echocardiographic investigation of 110 patients with different forms of stable arterial hypertension demonstrated a moderately close correlation between left-ventricular myocardial weight, and systolic and diastolic arterial blood pressure in patients with essential hypertension and chronic diffuse glomerulonephritis, and a weak correlation between left-ventricular myocardial weight and systolic pressure in patients with renovascular hypertension and chronic unilateral or predominantly unilateral pyelonephritis. Inadequate left-ventricular hypertrophy has similar incidence (15-20%) in patients with different forms of arterial hypertension, whereas excessive hypertrophy only occurs in patients with essential hypertension. The frequency of asymmetrical hypertrophy differs in the two groups.

[Effect of physical load adaptation on the age-related dynamics of the contractile function and weight of the human left ventricle]. / Vliianie adaptatsii k fizicheskim nagruzkam na vozrastnuiu dinamimku sokratitel'noi funktsii i massy levogo zheludochka serdtsa cheloveka.

Echocardiographic investigation of the mass and function of the left ventricle was undertaken on 110 trained to endurance and 100 nontrained young individuals 10 to 30 years of age. It is established that in the nontrained group aged from 10--12 up to 20--30 the mass of the left ventricle increases approximately by 50 g, which is over 70%. Correspondingly the end diastolic volume of the ventricle rises by 50 ml i. e. by 73%, approximately. The end systolic volume of the ventricle is increased only by 28 ml. Training to endurance resulted at the age of 10--12 years after 1 1/2--2 years of training (skiing) in an increase in the absolute mass of the left ventricle by 40 g, i. e. more than 50% as compared to the control group. During the next 10 years the mass of the left ventricle of the heart in the adapted and the nonadapted persons increased from different initial levels at the same rate--an average of 80%. These data are considered in the light of modern conceptions of the mechanism of cardiac hypertrophy.