1.
Chem Commun (Camb)
; 57(6): 797-800, 2021 Jan 18.
Artículo
en Inglés
| MEDLINE
| ID: mdl-33355564
RESUMEN
Caspase-3/8 are key members of the cysteine-aspartyl protease family with pivotal roles in apoptosis. We have designed and synthesized self-assembling probes, Nap-GFFpYDEVD-AFC and Nap-GFFpYIETD-AFC, with fluorescence 'turn-on' properties for real-time monitoring of Caspase-3/8 activity in living cells.