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1.
Bone Joint Res ; 8(1): 1-2, 2019 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-30800293
2.
Bone Joint J ; 100-B(8): 1043-1053, 2018 08.
Artículo en Inglés | MEDLINE | ID: mdl-30062939

RESUMEN

Aims: The aim of this study was to identify predictors of return to work (RTW) after revision lower limb arthroplasty in patients of working age in the United Kingdom. Patients and Methods: We assessed 55 patients aged ≤ 65 years after revision total hip arthroplasty (THA). There were 43 women and 12 men with a mean age of 54 years (23 to 65). We also reviewed 30 patients after revision total knee arthroplasty (TKA). There were 14 women and 16 men with a mean age of 58 years (48 to 64). Preoperatively, age, gender, body mass index, social deprivation, mode of failure, length of primary implant survival, work status and nature, activity level (University of California, Los Angeles (UCLA) score), and Oxford Hip and Knee Scores were recorded. Postoperatively, RTW status, Oxford Hip and Knee Scores, EuroQol-5D (EQ-5D), UCLA score, and Work, Osteoarthritis and Joint-Replacement Questionnaire (WORQ) scores were obtained. Univariate and multivariate analysis was performed. Results: Overall, 95% (52/55) of patients were working before their revision THA. Afterwards, 33% (17/52) RTW by one year, 48% (25/52) had retired, and 19% (10/52) were receiving welfare benefit. RTW was associated with age, postoperative Oxford Hip Score, early THA failure (less than two years), mode of failure dislocation, and contralateral revision (p < 0.05). No patient returned to work after revision for dislocation. Only age remained a significant factor on multivariate analysis (p = 0.003), with 79% (11/14) of those less than 50 years of age returning to work, compared with 16% (6/38) of those aged fifty years or over. Before revision TKA, 93% (28/30) of patients were working. Postoperatively only 7% (2/28) returned to work by one year, 71% (20/28) had retired, and 21% (6/28) were receiving welfare benefits. UCLA scores improved after 43% of revision THAs and 44% of revision TKAs. Conclusion: After revision THA, age is the most significant predictor of RTW: only 16% of those over 50 years old return to work. Fewer patients return to work after early revision THA and none after revision for dislocation. After revision TKA, patients rarely return to work: none return to heavy or moderate manual work. Cite this article: Bone Joint J 2018;100-B:1043-53.


Asunto(s)
Artroplastia de Reemplazo de Cadera/rehabilitación , Artroplastia de Reemplazo de Rodilla/rehabilitación , Ejercicio Físico/fisiología , Reinserción al Trabajo/estadística & datos numéricos , Adulto , Distribución por Edad , Factores de Edad , Anciano , Índice de Masa Corporal , Empleo , Femenino , Humanos , Masculino , Memoria Episódica , Persona de Mediana Edad , Medición de Resultados Informados por el Paciente , Falla de Prótesis/etiología , Infecciones Relacionadas con Prótesis/etiología , Reoperación/estadística & datos numéricos , Jubilación/estadística & datos numéricos , Reino Unido , Adulto Joven
3.
J Antimicrob Chemother ; 73(7): 1830-1840, 2018 07 01.
Artículo en Inglés | MEDLINE | ID: mdl-29554250

RESUMEN

Objectives: To evaluate putative anti-staphylococcal biofilm antibiotic combinations used in the management of periprosthetic joint infections (PJIs). Methods: Using the dissolvable bead biofilm assay, the minimum biofilm eradication concentration (MBEC) was determined for the most commonly used antimicrobial agents and combination regimens against staphylococcal PJIs. The established fractional inhibitory concentration (FIC) index was modified to create the fractional biofilm eradication concentration (FBEC) index to evaluate synergism or antagonism between antibiotics. Results: Only gentamicin (MBEC 64 mg/L) and daptomycin (MBEC 64 mg/L) were observed to be effective antistaphylococcal agents at clinically achievable concentrations. Supplementation of gentamicin with daptomycin, vancomycin or ciprofloxacin resulted in a similar or lower MBEC than gentamicin alone (FBEC index 0.25-2). Conversely, when rifampicin, clindamycin or linezolid was added to gentamicin, there was an increase in the MBEC of gentamicin relative to its use as a monotherapy (FBEC index 8-32). Conclusions: This study found that gentamicin and daptomycin were the only effective single-agent antibiotics against established Staphylococcus biofilms. Interestingly the addition of a bacteriostatic antibiotic was found to antagonize the ability of gentamicin to eradicate Staphylococcus biofilms.


Asunto(s)
Antibacterianos/farmacología , Biopelículas/efectos de los fármacos , Staphylococcus/efectos de los fármacos , Daptomicina/farmacología , Antagonismo de Drogas , Sinergismo Farmacológico , Gentamicinas/farmacología , Humanos , Prótesis Articulares/microbiología , Staphylococcus aureus Resistente a Meticilina/efectos de los fármacos , Pruebas de Sensibilidad Microbiana , Staphylococcus/fisiología , Vancomicina/farmacología
4.
J Microbiol Methods ; 142: 46-51, 2017 11.
Artículo en Inglés | MEDLINE | ID: mdl-28870772

RESUMEN

In vitro biofilm assays are a vital first step in the assessment of therapeutic effectiveness. Current biofilm models have been found to be limited by throughput, reproducibility, and cost. We present a novel in vitro biofilm model, utilising a sodium alginate substratum for surface biofilm colony formation, which can be readily dissolved for accurate evaluation of viable organisms. The dissolving bead biofilm assay was evaluated using a range of clinically relevant strains. The reproducibility and responsiveness of the assay to an antimicrobial challenge was assessed using standardised methods. Cryo-scanning electron microscopy was used to image biofilm colonies. Biofilms were grown for 20h prior to testing. The model provides a reproducible and responsive assay to clinically-relevant antimicrobial challenges, as defined by established guidelines. Moreover cryo-scanning electron microscopy demonstrates that biofilm formation is localised exclusively to the alginate bead surface. Our results suggest that this simple model provides a robust and adaptable assay for the investigation of bacterial biofilms.


Asunto(s)
Antibacterianos/farmacología , Biopelículas/efectos de los fármacos , Biopelículas/crecimiento & desarrollo , Farmacorresistencia Bacteriana/fisiología , Gentamicinas/farmacología , Alginatos/química , Microscopía por Crioelectrón , Enterococcus faecalis/crecimiento & desarrollo , Enterococcus faecalis/aislamiento & purificación , Escherichia coli/crecimiento & desarrollo , Escherichia coli/aislamiento & purificación , Ácido Glucurónico/química , Ácidos Hexurónicos/química , Humanos , Klebsiella pneumoniae/crecimiento & desarrollo , Klebsiella pneumoniae/aislamiento & purificación , Pruebas de Sensibilidad Microbiana , Microscopía Electrónica de Rastreo , Pseudomonas aeruginosa/crecimiento & desarrollo , Pseudomonas aeruginosa/aislamiento & purificación , Staphylococcus aureus/crecimiento & desarrollo , Staphylococcus aureus/aislamiento & purificación , Streptococcus mutans/crecimiento & desarrollo , Streptococcus mutans/aislamiento & purificación
5.
Bone Joint J ; 99-B(8): 1037-1046, 2017 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-28768780

RESUMEN

AIMS: Little is known about employment following total knee arthroplasty (TKA). This study aims to identify factors which predict return to work following TKA in patients of working age in the United Kingdom. PATIENTS & METHODS: We prospectively assessed 289 patients (289 TKAs) aged ≤ 65 years who underwent TKA between 2010 and 2013. There were 148 women. The following were recorded pre-operatively: age, gender, body mass index, social deprivation, comorbidities, indication for surgery, work status and nature of employment, activity level as assessed by the University of California, Los Angeles (UCLA) activity score and Oxford Knee Score (OKS). The intention of patients to return to work or to retire was not assessed pre-operatively. At a mean of 3.4 years (2 to 4) post-operatively, the return to work status, OKS, the EuroQol-5 dimensions (EQ-5D) score, UCLA activity score and Work, Osteoarthritis and joint-Replacement (WORQ) score were obtained. Univariate and multivariate analyses were performed. RESULTS: Of 261 patients (90%) who were working before TKA, 105 (40%) returned to any job, including 89 (34%) who returned to the same job at a mean of 13.5 weeks (2 to 104) post-operatively. A total of 108 (41%) retired following TKA and 18 remained on welfare. Patients not working before the operation did not return to work. Median UCLA scores improved in 125 patients (58%) from 4 (mild activity) to 6 (moderate activity) (p < 0.001). Significant (p < 0.05) factors which were predictive of return to any work included age, heavy or moderate manual work, better post-operative UCLA, OKS and EQ-5D general health scores. Significant predictive factors of return to the same work included age, heavy or moderate manual work and post-operative OKS. Multivariate analysis confirmed heavy or moderate manual work and age to independently predict a return to either any or the same work. All patients aged < 50 years who were working pre-operatively returned to any work as did 60% of those aged between 50 and 54 years, 50% of those aged between 55 and 59 years and 24% those aged between 60 and 65 years. CONCLUSION: If working pre-operatively, patients aged < 50 years invariably returned to work following TKA, but only half of those aged between 50 to 60 years returned. High post-operative activity levels and patient reported outcome measures do not predict return to work following TKA. Cite this article: Bone Joint J 2017;99-B:1037-46.


Asunto(s)
Artroplastia de Reemplazo de Rodilla/métodos , Ejercicio Físico/fisiología , Osteoartritis de la Rodilla/cirugía , Satisfacción del Paciente , Reinserción al Trabajo , Adulto , Anciano , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Osteoartritis de la Rodilla/rehabilitación , Periodo Posoperatorio , Estudios Retrospectivos , Reino Unido
6.
Bone Joint J ; 98-B(12): 1625-1634, 2016 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-27909124

RESUMEN

AIMS: Risk of revision following total knee arthroplasty (TKA) is higher in patients under 55 years, but little data are reported regarding non-revision outcomes. This study aims to identify predictors of dissatisfaction in these patients. PATIENTS AND METHODS: We prospectively assessed 177 TKAs (157 consecutive patients, 99 women, mean age 50 years; 17 to 54) from 2008 to 2013. Age, gender, implant, indication, body mass index (BMI), social deprivation, range of movement, Kellgren-Lawrence (KL) grade of osteoarthritis (OA) and prior knee surgery were recorded. Pre- and post-operative Oxford Knee Score (OKS) as well as Short Form-12 physical (PCS) and mental component scores were obtained. Post-operative range of movement, complications and satisfaction were measured at one year. RESULTS: Overall, 44 patients with 44 TKAs (24.9%) under 55 years of age were unsure or dissatisfied with their knee. Significant predictors of dissatisfaction on univariate analysis included: KL grade 1/2 OA (59% dissatisfied), poor pre-operative OKS, complications, poor improvements in PCS and OKS and indication (primary OA 19% dissatisfied, previous meniscectomy 41%, multiply operated 42%, other surgery 29%, BMI > 40 kg/m2 31%, post-traumatic OA 45%, and inflammatory arthropathy 5%). Poor pre-operative OKS, poor improvement in OKS and post-operative stiffness independently predicted dissatisfaction on multivariate analysis. CONCLUSION: Patients receiving TKA younger than 55 years old should be informed about the increased risks of dissatisfaction. Offering TKA in KL 1/2 is questionable, with a dissatisfaction rate of 59%. Cite this article: Bone Joint J 2016;98-B:1625-34.


Asunto(s)
Artroplastia de Reemplazo de Rodilla/rehabilitación , Prótesis de la Rodilla , Osteoartritis de la Rodilla/cirugía , Satisfacción del Paciente/estadística & datos numéricos , Adolescente , Adulto , Factores de Edad , Anciano , Anciano de 80 o más Años , Artroplastia de Reemplazo de Rodilla/efectos adversos , Artroplastia de Reemplazo de Rodilla/métodos , Índice de Masa Corporal , Femenino , Humanos , Articulación de la Rodilla/diagnóstico por imagen , Articulación de la Rodilla/fisiopatología , Masculino , Persona de Mediana Edad , Pobreza/estadística & datos numéricos , Pronóstico , Estudios Prospectivos , Diseño de Prótesis , Radiografía , Rango del Movimiento Articular , Recuperación de la Función , Factores de Riesgo , Índice de Severidad de la Enfermedad , Resultado del Tratamiento , Adulto Joven
7.
Bone Joint J ; 98-B(10): 1376-1381, 2016 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-27694592

RESUMEN

AIMS: This is the first prospective study to report the pre- and post-operative patient reported outcomes and satisfaction scores following excision of interdigital Morton's neuroma. PATIENTS AND METHODS: Between May 2006 and April 2013, we prospectively studied 99 consecutive patients (111 feet) who were to undergo excision of a Morton's neuroma. There were 78 women and 21 men with a mean age at the time of surgery of 56 years (22 to 78). Patients completed the Manchester-Oxford Foot Questionnaire (MOXFQ), Short Form-12 (SF-12) and a supplementary patient satisfaction survey three months pre-operatively and six months post-operatively. RESULTS: Statistically significant differences were found between the mean pre- and post-operative MOXFQ and the physical component of the SF-12 scores (p = 0.00081 and p = 0.00092 respectively). Most patients reported their overall satisfaction as excellent (n = 49, 49.5%) or good (n = 29, 29.3%), but ten patients were dissatisfied, reporting poor (n = 8, 8.1%) or very poor (n = 2, 2.0%) results. Only 63 patients (63%) were pain-free at follow-up: in eight patients (8.1%), the MOXFQ score worsened. There was no statistically significant difference in outcome between surgery on single or multiple sites. However, the MOXFQ scores were significantly worse after revision surgery (p = 0.004). CONCLUSIONS: The patient-reported outcomes after resection of a symptomatic Morton's neuroma are acceptable but may not be as good as earlier studies suggest. Surgery at several sites can be undertaken safely but caution should be exercised when considering revision surgery. Cite this article: Bone Joint J 2016;98-B:1376-81.


Asunto(s)
Pie/cirugía , Neuroma de Morton/cirugía , Procedimientos Ortopédicos/métodos , Satisfacción del Paciente , Adulto , Anciano , Femenino , Estudios de Seguimiento , Pie/fisiopatología , Humanos , Masculino , Persona de Mediana Edad , Neuroma de Morton/fisiopatología , Periodo Posoperatorio , Estudios Prospectivos , Rango del Movimiento Articular , Encuestas y Cuestionarios , Resultado del Tratamiento , Adulto Joven
8.
Arch Orthop Trauma Surg ; 136(9): 1317-1323, 2016 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-27484875

RESUMEN

INTRODUCTION: The aim of this study was to assess the independent effect of radiographic measures of implant position, relative to pre-operative anatomical assessment, on the functional outcome of total hip arthroplasty according to change in the Oxford hip score (OHS) 1 year post surgery. METHODS: A prospective cohort study was preformed to assess whether improvement in functional outcome (change in OHS at 1 year) and the relationship with femoral offset and length, and acetabular offset and height. After a power calculation 359 patients were recruited to the study and radiographic measures were performed by blinded observers. Regression analysis was used to assess the independent effect of the four radiographic measurements after adjusting for confounding variables. RESULTS: There was a significant (p < 0.001) decrease in acetabular offset [5.3 mm, 95 % confidence interval (CI) 4.4-6.2] and increase in femoral offset (6.1 mm, 95 % CI 5.4-6.8). Hence there was no significant change in overall offset. Femoral offset was the only radiographic measure to be achieved statistical significance (r = 0.198, 95 % CI 0.063-0.333, p = 0.004) in relation to clinical outcome, with increasing offset being associated with a greater improvement in the OHS. On combining femoral and acetabular offset increasing offset was associated with a greater improvement in the OHS (r = 0.10, 95 % CI 0.01-0.19, p = 0.04). CONCLUSION: This study supports the long-held biomechanical theory of medialisation of the acetabular component with compensatory increased femoral offset results in improved functional outcome.


Asunto(s)
Artroplastia de Reemplazo de Cadera/métodos , Articulación de la Cadera/diagnóstico por imagen , Prótesis de Cadera , Ajuste de Prótesis , Anciano , Estudios de Cohortes , Femenino , Humanos , Masculino , Satisfacción del Paciente
9.
Case Rep Rheumatol ; 2016: 9759182, 2016.
Artículo en Inglés | MEDLINE | ID: mdl-27437158

RESUMEN

We report an unusual case of a 65-year-old lady with CREST syndrome with multiple upper and lower limb calcinosis, who presented with severe shoulder pain and stiffness, with widespread intra- and extra-articular calcinosis, which was refractory to conservative measures. We were able to identify the main cause of her symptoms through serial diagnostic injections as calcific biceps tendinosis. We will discuss her assessment and surgical management and the pathophysiology and various treatment modalities for managing the soft tissue calcinosis in rheumatological diseases.

10.
Arch Orthop Trauma Surg ; 136(2): 165-74, 2016 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-26667621

RESUMEN

INTRODUCTION: The treatment of adult non-traumatic avascular necrosis of the femoral head (AVN; N-ANFH) within an estimated incidence of 5000-7000 cases per annum in Germany remains a challenge. Risk factors include steroids, alcohol abuse, chemotherapy and immunosuppressive medication, but a genetic predisposition has been suggested. Early diagnosis of this often bilateral disease process is essential for successful conservative or joint preserving surgical management. In this review, we present the update German consensus S3 guideline "diagnosis and management for N-ANFH" as a concise summary. MATERIALS AND METHODS: This systematic review is based on the published literature from January 1, 1970 to April 31, 2013 (German and English language). Inclusion criteria were systematic reviews, meta-analyses and relevant peer review publications. We identified a total of 3715 related publications, of which 422 were suitable according to the SIGN criteria, but only 159 fulfilled our inclusion criteria. RESULTS AND CONCLUSIONS: Clinical suspicion of N-ANFH mandates radiographic evaluation. If radiographs are normal MRI scans are recommended, which should be evaluated according to the ARCO-classification. Differential diagnoses include transient osteoporosis, bone bruise, insufficiency fracture and destructive arthropathy. Untreated, subchondral fractures commonly occur within 2 years, during which the risk for contralateral involvement is high-thereafter unlikely. Conservative management with Ilomedin and Alendronat can be tried, but other pharmacological or physical treatments are inappropriate. No specific joint preserving procedure can be recommended, but core decompression should be considered in early stages if necrosis is <30 %. In ARCO stages IIIc or IV total hip arthroplasty (THA) should be contemplated, which offers similar outcome compared to osteoarthritis. Young age is the main risk factor for higher revision rates after THA for N-ANFH.


Asunto(s)
Necrosis de la Cabeza Femoral/diagnóstico , Necrosis de la Cabeza Femoral/terapia , Adulto , Alendronato/uso terapéutico , Artroplastia de Reemplazo de Cadera , Conservadores de la Densidad Ósea/uso terapéutico , Descompresión Quirúrgica , Diagnóstico Diferencial , Prótesis de Cadera , Humanos , Iloprost/uso terapéutico , Guías de Práctica Clínica como Asunto , Vasodilatadores/uso terapéutico
11.
Arch Orthop Trauma Surg ; 135(5): 703-8, 2015 May.
Artículo en Inglés | MEDLINE | ID: mdl-25739993

RESUMEN

INTRODUCTION: Despite the clinical success of cemented TKA, aseptic loosening of the tibial component remains a potential long-term complication. Considering the constantly growing revision burden, there is a need for clarification regarding controversial views on primary fixation techniques. In this retrospective analysis, surface (SC) or full cementation (FC) of tibial components was compared in a matched-pair and long-term setting. METHODS: Matching pairs were identified in a patient series from 1989 to 1994. Hence, 25 primary TKA (SC) were compared to 42 TKA (FC). The study population included 34 patients with rheumatoid arthritis. Patients were matched in a 1:1.7 fashion according to age, gender and initial diagnosis. Outcome was assessed by multiple clinical parameters, detailed radiographic evaluation and survivorship analysis. RESULTS: Clinical follow-up (FU) was at 10.3 years (range 1.5-15.6) for the SC and 12 years (range 0.2-16.2) for the FC group. Survivorship at 10 years was 100 % for the surface cemented trays and 93.3 % (95 % CI 80.5-100) for the fully cemented implants considering aseptic loosening as endpoint (p = 0.3918). Improvement of the AKS Score was greater in the SC group (p = 0.044) and patients in this group were more satisfied (p = 0.013). For any other clinical parameter, no difference could be observed (p > 0.05). CONCLUSION: Results of this study showed no statistically significant difference regarding long-term survivorship for the two cementing techniques. This finding questions the claimed advantage of full cementation for tibial components. The presented data do not support the concern that surface cementation results in insufficient fixation in patients with rheumatoid arthritis.


Asunto(s)
Artroplastia de Reemplazo de Rodilla/métodos , Cementación/métodos , Prótesis de la Rodilla , Anciano , Artritis Reumatoide/cirugía , Femenino , Estudios de Seguimiento , Humanos , Masculino , Análisis por Apareamiento , Persona de Mediana Edad , Evaluación del Resultado de la Atención al Paciente , Satisfacción del Paciente , Estudios Retrospectivos
12.
Surgeon ; 12(2): 78-81, 2014 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-24090678

RESUMEN

BACKGROUND: Wrist arthrodesis has been established as a mainstay form of surgical intervention in the rheumatoid wrist. Despite this however, there is a distinct lack of patient-reported outcome measure (PROM) studies justifying the efficacy of this procedure in rheumatoid disease. The aim of this study was to report any change in function or pain following the tunnel Mannerfelt wrist arthrodesis in a single surgeon series of rheumatoid patients over a 6 year period. METHODS: 14 consecutive patients (15 wrists) who had undergone the Mannerfelt wrist arthrodesis were followed prospectively with a mean follow up period of 45 months. No patients were lost to follow up. The primary outcome measures included the validated Patient Rated Wrist Evaluation (PRWE) questionnaire and a satisfaction questionnaire. RESULTS: The mean total pain score improved from 41 points preoperatively to 14.2 points postoperatively correlating with a 65.4% improvement in overall pain outcomes. The mean total functional score improved from 83.7 points preoperatively to 45.5 points postoperatively demonstrating a 45.6% improvement in overall function at the time of follow up. CONCLUSIONS: All patients reported an overall improvement in pain and functional capacity. The satisfaction results were excellent. All patients reported that they would elect to have the procedure again with the vast majority being 'very pleased' with the outcome of their surgery (93.7% very pleased and 6.3% fairly pleased). The procedure enjoyed favourable mid-term results and we recommend the tunnel Mannerfelt wrist arthrodesis for improving both pain and level of function in this group of patients.


Asunto(s)
Artritis Reumatoide/cirugía , Artrodesis/métodos , Articulación de la Muñeca/cirugía , Anciano , Artritis Reumatoide/diagnóstico por imagen , Femenino , Estudios de Seguimiento , Humanos , Masculino , Satisfacción del Paciente , Estudios Prospectivos , Radiografía , Encuestas y Cuestionarios , Factores de Tiempo , Resultado del Tratamiento , Articulación de la Muñeca/diagnóstico por imagen
13.
Knee ; 20(6): 437-41, 2013 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-23993274

RESUMEN

BACKGROUND: There is conflicting evidence as to whether diabetes mellitus influences the functional outcome and patient satisfaction after a total knee replacement (TKR). The aim of this study was to assess the effect of diabetes upon the Oxford knee score (OKS), short form (SF)-12, and patient satisfaction after TKR. METHODS: Prospective pre- and post-operative (one year) OKS and SF-12 scores for 2389 patients undergoing primary TKR were compiled, of which 275 (12%) patients suffered with diabetes. Patient satisfaction was assessed at one year. RESULTS: Patients with diabetes were more likely to have a greater level of comorbidity (p<0.001), and a worse pre-operative OKS and SF-12 score (p<0.02), compared to those patients without diabetes. Diabetes was not a significant (p>0.41) independent predictor of post-operative OKS or the SF-12 physical score on multivariable analysis. Although, factors more prevalent within the diabetic cohort (heart disease, vascular disease, liver disease, anaemia, depression, back pain, worse pre-operative OKS and SF-12 score) were found to be independent predictors of post-operative OKS and SF-12 physical score. Interestingly, diabetes was associated with a significantly greater improvement in mental wellbeing (SF-12 mental component), which was confirmed on multivariable analysis. Patient satisfaction was not influenced by a concomitant diagnosis of diabetes (p=0.57). CONCLUSION: The outcome of TKR as assessed by the OKS, SF-12, and overall patient satisfaction rates are not influenced by diabetes per se, although factors more prevalent within this population result in a worse post-operative outcome. LEVEL OF EVIDENCE: prospective cohort study, level III.


Asunto(s)
Artroplastia de Reemplazo de Rodilla/métodos , Diabetes Mellitus/epidemiología , Osteoartritis de la Rodilla/epidemiología , Osteoartritis de la Rodilla/cirugía , Índice de Severidad de la Enfermedad , Adulto , Factores de Edad , Anciano , Anciano de 80 o más Años , Artroplastia de Reemplazo de Rodilla/efectos adversos , Estudios de Casos y Controles , Diabetes Mellitus/diagnóstico , Diabetes Mellitus/cirugía , Femenino , Estudios de Seguimiento , Humanos , Prótesis de la Rodilla , Masculino , Osteoartritis de la Rodilla/diagnóstico , Dimensión del Dolor , Dolor Postoperatorio/fisiopatología , Satisfacción del Paciente/estadística & datos numéricos , Valor Predictivo de las Pruebas , Estudios Prospectivos , Falla de Prótesis , Recuperación de la Función , Valores de Referencia , Medición de Riesgo , Factores Sexuales , Resultado del Tratamiento
14.
Case Rep Rheumatol ; 2013: 759193, 2013.
Artículo en Inglés | MEDLINE | ID: mdl-23691417

RESUMEN

Hemiarthroplasty of the shoulder can be a safe and an effective treatment for pain in patients with rheumatoid arthritis. Many complications have been previously described in the literature; the most common of which are dislocation, loosening, periprosthetic fractures, and infection. We report a patient who presented with a discharging sinus over the tip of the acromium which was created by the displacement of the prosthesis and erosion of the AC joint and distal clavicle. The erosion of the distal clavicle and AC joint caused the remaining proximal clavicle to become mobile and displaced posteriorly; this spike of clavicle was then able to penetrate the trapezius muscle and eventually the skin causing an aseptic sinus. This was successfully treated with the exploration and excision of the distal 2 cm of the clavicle.

15.
Arch Orthop Trauma Surg ; 133(5): 695-700, 2013 May.
Artículo en Inglés | MEDLINE | ID: mdl-23443526

RESUMEN

INTRODUCTION: Expectations of patients requiring total hip replacement have become higher than in the past and are often well beyond pain relief and improved mobility. Return to work and sporting activity are important factors to be considered when advising patients preoperatively. The objective of this study was to analyse the return to sports and work rates in patients still in employment and to analyse potential influencing factors. MATERIALS AND METHODS: Patients under the age of 65 who had a total hip replacement performed at a university teaching hospital were identified from the local arthroplasty database and contacted. Pre and postoperative levels of sporting activity and work were recorded. We also recorded the time point at which they returned to these activities. RESULTS: 285 total hip replacements were carried out on 239 patients. At the time of follow-up 170 of the patients were working. The mean length of time to return to work was 13.9 weeks (SD 7.7). 78 % returned to work without any restrictions, 18.6 % in heavy manual jobs. The mean time taken to return to sports or similar physical activities was 18.8 weeks (SD 8.8) weeks. Those with a lower body mass index returned to work and sporting activities faster. CONCLUSIONS: Our data show that the majority of patients undergoing total hip replacement can expect to return to work and sporting activities within 4-6 months. Activities at work are often initially limited and physical performance may not fully return to the expected level. Patients with a high body mass index take longer to return to work and sporting activities.


Asunto(s)
Artroplastia de Reemplazo de Cadera/rehabilitación , Reinserción al Trabajo , Deportes , Adolescente , Adulto , Femenino , Humanos , Masculino , Persona de Mediana Edad , Actividad Motora , Recuperación de la Función , Adulto Joven
16.
Bone Joint J ; 95-B(1): 52-8, 2013 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-23307673

RESUMEN

We assessed the effect of social deprivation upon the Oxford knee score (OKS), the Short-Form 12 (SF-12) and patient satisfaction after total knee replacement (TKR). An analysis of 966 patients undergoing primary TKR for symptomatic osteoarthritis (OA) was performed. Social deprivation was assessed using the Scottish Index of Multiple Deprivation. Those patients that were most deprived underwent surgery at an earlier age (p = 0.018), were more likely to be female (p = 0.046), to endure more comorbidities (p = 0.04) and to suffer worse pain and function according to the OKS (p < 0.001). In addition, deprivation was also associated with poor mental health (p = 0.002), which was assessed using the mental component (MCS) of the SF-12 score. Multivariable analysis was used to identify independent predictors of outcome at one year. Pre-operative OKS, SF-12 MCS, back pain, and four or more comorbidities were independent predictors of improvement in the OKS (all p < 0.001). Pre-operative OKS and improvement in the OKS were independent predictors of dissatisfaction (p = 0.003 and p < 0.001, respectively). Although improvement in the OKS and dissatisfaction after TKR were not significantly associated with social deprivation per se, factors more prevalent within the most deprived groups significantly diminished their improvement in OKS and increased their rate of dissatisfaction following TKR.


Asunto(s)
Artroplastia de Reemplazo de Rodilla , Indicadores de Salud , Osteoartritis de la Rodilla/cirugía , Satisfacción del Paciente/estadística & datos numéricos , Clase Social , Encuestas y Cuestionarios , Adulto , Anciano , Anciano de 80 o más Años , Análisis de Varianza , Estudios de Cohortes , Femenino , Humanos , Modelos Lineales , Masculino , Persona de Mediana Edad , Análisis Multivariante , Resultado del Tratamiento
17.
Arch Orthop Trauma Surg ; 132(11): 1619-23, 2012 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-22763863

RESUMEN

INTRODUCTION: Tears of the abductor mechanism of the hip are well recognized, but poorly understood. Little is known of the effect of demographics and pathology on prevalence of abductor mechanism tears or the impact on clinical outcome. METHODS: This prospective study analysed the effect of age, gender, medical co-morbidity and social deprivation on prevalence of abductor mechanism tears of the hip in 835 consecutive patients undergoing total hip arthroplasty (THA) between 2003 and 2011. Effect on clinical outcome relating to presence of abductor mechanism tear was analysed in a subset at pre-op and at 1 year post-operation using the Oxford hip score (OHS). RESULTS: The prevalence of abductor mechanism tears was 25.4 % (n = 212). Female patients (p < 0.001), older patients (p = 0.001) and those of lower socioeconomic status (p < 0.001) were significantly more likely to have a pre-operative abductor mechanism tear. In older socially deprived females the predicted rate of tear is 70.9 %. The aetiology of the hip disease (p = 0.593) or presence of any specific co-morbidity (p = 0.085-0.929) had no significant effect on the prevalence of abductor mechanism tears. In patients with protrusion or dysplasia there was an increased prevalence of tears (p = 0.002). There was no significant difference in pre-operative (p = 0.775) or post-operative (p = 0.604) OHSs regardless of the tears when the tears were recognized and treated at the time of THA. CONCLUSIONS: Tears are increasingly prevalent in women of advancing years and lower socioeconomic status which should be considered when planning operative approach in this demographic. When recognised and repaired there is no difference in the clinical outcome for those with abductor mechanism tears of the hip.


Asunto(s)
Lesiones de la Cadera/epidemiología , Lesiones de la Cadera/cirugía , Articulación de la Cadera , Artropatías/epidemiología , Artropatías/cirugía , Músculo Esquelético/lesiones , Adulto , Factores de Edad , Anciano , Anciano de 80 o más Años , Artroplastia de Reemplazo de Cadera , Femenino , Humanos , Artropatías/etiología , Masculino , Persona de Mediana Edad , Prevalencia , Estudios Prospectivos , Rango del Movimiento Articular , Rotura , Factores Sexuales , Clase Social , Resultado del Tratamiento
18.
Orthopade ; 41(6): 442-51, 2012 Jun.
Artículo en Alemán | MEDLINE | ID: mdl-22622658

RESUMEN

Hip resurfacing is a common method for therapy of coxarthritis and is currently under discussion. The aim of this study was to analyze hip resurfacing follow-up studies with more than 5 years follow-up time. A total of 17 studies which matched the inclusion criteria were analyzed. The survival rate after 5-6 years was 96.3%, after 7-8 years 93.8% and after 9-10 years 90%. Young men with primary coxarthritis and surgery by an experienced surgeon showed the best results. The main causes for revision were aseptic loosening with 34.4% and fracture of the proximal femur with 31.9%. Dislocation as a cause for revision was rare and occurred in 2.8% of all cases. Hip resurfacing showed worse results than conventional hip arthroplasty. The risk for complications was high especially for women, with small prostheses and in patients with suboptimal positioning of the prosthesis.


Asunto(s)
Prótesis de Cadera , Osteoartritis de la Cadera/cirugía , Complicaciones Posoperatorias/etiología , Falla de Prótesis , Femenino , Estudios de Seguimiento , Humanos , Masculino , Complicaciones Posoperatorias/cirugía , Diseño de Prótesis , Reoperación , Tasa de Supervivencia
19.
Arch Orthop Trauma Surg ; 132(3): 411-27, 2012 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-22134618

RESUMEN

The optimal method for acetabular socket fixation remains controversial. We present a critical analysis of the current evidence from a systemic literature review of comparative studies, long-term case series, prior literature reviews, meta-analysis, and national arthroplasty registry data for cemented and uncemented acetabular components to determine the respective survivorship rates, overall risk of re-operation, dislocation rates, and wear-related complications. Using contemporary techniques, both cemented and uncemented sockets can yield good long-term results, but our evaluation suggests that the overall/all cause re-operation risk is lower for cemented fixation. Until and unless crosslinked polyethylene (PE) liners or alternative bearings can prove to yield superior outcome in the future, the cemented PE cup remains the gold standard, in all age groups, by which every acetabular component should be compared.


Asunto(s)
Acetábulo , Artroplastia de Reemplazo de Cadera , Cementación , Artroplastia de Reemplazo de Cadera/métodos , Luxación de la Cadera/etiología , Prótesis de Cadera/efectos adversos , Humanos , Osteólisis/etiología , Falla de Prótesis , Reoperación , Análisis de Supervivencia
20.
Orthopade ; 37(9): 904, 906-13, 2008 Sep.
Artículo en Alemán | MEDLINE | ID: mdl-18685826

RESUMEN

BACKGROUND: Acetabular revision in total hip arthroplasty (THA), especially for loose or migrated cup components with collateral bone loss, remains a great surgical challenge. The aim should always be a functionally favorable reconstruction of the rotation center with sufficient load capacity of the acetabulum. Commonly used implants in Europe are the Mueller ring, the Ganz ring, and the Burch-Schneider cage. PATIENTS AND METHODS: We report our results of 298 patients (298 hips) with a median follow-up period of 4 (range 0-17) years in a retrospective series. RESULTS: Follow-up data were available in 224 cases (75%). A radiographic examination was performed in 176 (59%) patients. Another 54 patients (18%) had died in the follow-up period, while another three patients (1%) were lost to follow-up. Eighteen patients (16%) underwent re-revision, in nine cases for aseptic loosening and in the remaining nine cases for infection. In seven additional cases (2%), radiological and clinical failure was found during follow-up. The overall survival rate was 94% at 5 years and 89% at 8 years. CONCLUSION: Revision THA using acetabular reinforcement rings results in acceptable midterm results. However, septic complications and lysis of the bone graft with consecutive failure of the reinforcement ring remain problematic.


Asunto(s)
Acetábulo/cirugía , Artroplastia de Reemplazo de Cadera/instrumentación , Complicaciones Posoperatorias/cirugía , Falla de Prótesis , Acetábulo/diagnóstico por imagen , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Complicaciones Posoperatorias/diagnóstico por imagen , Diseño de Prótesis , Infecciones Relacionadas con Prótesis/diagnóstico por imagen , Infecciones Relacionadas con Prótesis/cirugía , Radiografía , Reoperación
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