RESUMEN
QUESTION UNDER STUDY: Influenza is a viral infection caused by a pathogen with considerable ability for genetic mutation, which is responsible for seasonal outbreaks as well as pandemics. This article presents the results of epidemiological and virological monitoring of four successive influenza outbreaks in the French armed forces, for the period 2008 to 2012. METHODS: The main events monitored were acute respiratory infection (ARI). Weekly incidence rates were calculated by relating cases to the number of servicepersons monitored. RESULTS: In continental France, the incidence rates for ARI and for medical consultation attributable to influenza were highest during the pandemic and decreased to reach their lowest values in 20102011 and 20112012. In terms of virological results, the 20082009 outbreak was mainly due to the A(H3N2) virus, while the 20092010 pandemic and the following season saw the emergence of the A(H1N1) pdm09 strain. The last season 20112012 was characterised by a predominant circulation of A(H3N2) viruses. CONCLUSIONS: Despite some limitations, the MISS represents a good source of information about influenza in young people. Virological results are compatible with those reported by most other influenza surveillance networks, but could be improved by a better knowledge of the other respiratory viruses in circulation in the military community.
Asunto(s)
Subtipo H1N1 del Virus de la Influenza A , Subtipo H3N2 del Virus de la Influenza A , Gripe Humana/epidemiología , Personal Militar/estadística & datos numéricos , Pandemias/estadística & datos numéricos , Adulto , Monitoreo Epidemiológico , Femenino , Francia/epidemiología , Humanos , Gripe Humana/fisiopatología , Gripe Humana/virología , Masculino , Infecciones del Sistema Respiratorio/epidemiología , Infecciones del Sistema Respiratorio/fisiopatología , Infecciones del Sistema Respiratorio/virología , Adulto JovenRESUMEN
We report 3 clinical cases of septic nonunions of lower limb long bones in which the pathogenicity of Propionibacterium acnes was retained after several weeks of poor outcome. The patients had fractures that were treated by internal fixation, without initially suspected infection. The diagnosis of delayed union coincided with the onset of treatment. Support was performed in 2 steps, allowing for the collection of several deep samples that were referred for microbiological analysis. Molecular techniques for microbiological investigation were performed on perioperative samples and were not contributive. The detection of P acnes, which was identified after several days of incubation, prompted us to consider the role of this bacterium. The presence of P acnes is regularly interpreted as contamination of samples during collection or handling in the laboratory. A multidisciplinary decision to make the diagnosis of surgical site infection with P acnes and specific antibiotic treatment for several months led to consolidation in all the patients. The ability of bacteria of the genus Propionibacterium to cause insidious surgical site infections should not be underestimated, and more extensive sample incubation is essential to diagnose such infections.
Asunto(s)
Amoxicilina/administración & dosificación , Fijación Interna de Fracturas/efectos adversos , Fracturas no Consolidadas/etiología , Extremidad Inferior , Propionibacterium acnes/aislamiento & purificación , Rifampin/administración & dosificación , Infección de la Herida Quirúrgica , Fracturas de la Tibia/cirugía , Adulto , Antibacterianos/administración & dosificación , Fijación Interna de Fracturas/métodos , Curación de Fractura/efectos de los fármacos , Humanos , Extremidad Inferior/patología , Extremidad Inferior/fisiopatología , Extremidad Inferior/cirugía , Persona de Mediana Edad , Infección de la Herida Quirúrgica/tratamiento farmacológico , Infección de la Herida Quirúrgica/microbiología , Infección de la Herida Quirúrgica/fisiopatología , Resultado del TratamientoRESUMEN
We report three cases of pruritic dermatitis with erythematous maculopapules, having a similar clinical presentation, in summer, and caused by two different arthropods. In wandering diagnosis since sometimes several months, patients have made entomologic investigations in their home. Two of three samples, have shown an infestation by Anobium punctatum, the common furniture beetle, a xylophagous beetle (usually harmless for human). It may be parasited by Pyemotes ventricosus, a mite known since the 19th century to cause this type of hurt. The third sample contained Cimex lectularius or bedbug, haematophagous insect, classically looked for in endemic zone.
Asunto(s)
Artrópodos , Dermatitis/etiología , Mordeduras y Picaduras de Insectos/complicaciones , Anciano , Animales , Chinches , Femenino , Humanos , Mordeduras y Picaduras de Insectos/diagnóstico , Masculino , Persona de Mediana Edad , Ácaros , Estaciones del Año , Adulto JovenRESUMEN
Clinicians are generally familiar with Acinetobacter baumannii as an aetiological agent of serious nosocomial infections in intensive care units. Other Acinetobacter species can also be responsible for life-threatening sepsis. Here, we report about a bacteraemia caused by Acinetobacter parvus, community-acquired, identified with a 16S rRNA gene sequence analysis and the MALDI-TOF mass spectrometry system.
Asunto(s)
Infecciones por Acinetobacter/diagnóstico , Infecciones por Acinetobacter/microbiología , Acinetobacter/aislamiento & purificación , Bacteriemia/diagnóstico , Bacteriemia/microbiología , Infecciones Comunitarias Adquiridas/diagnóstico , Infecciones Comunitarias Adquiridas/microbiología , Acinetobacter/química , Acinetobacter/clasificación , Acinetobacter/genética , Anciano de 80 o más Años , ADN Bacteriano/química , ADN Bacteriano/genética , ADN Ribosómico/química , ADN Ribosómico/genética , Humanos , Masculino , ARN Ribosómico 16S/genética , Análisis de Secuencia de ADN , Espectrometría de Masa por Láser de Matriz Asistida de Ionización DesorciónAsunto(s)
Enfermedades Pulmonares/microbiología , Infecciones por Mycobacterium/microbiología , Mycobacterium/clasificación , Adulto , Antibacterianos/uso terapéutico , Bahrein/epidemiología , Femenino , Francia/epidemiología , Humanos , Enfermedades Pulmonares/epidemiología , Masculino , Infecciones por Mycobacterium/epidemiologíaAsunto(s)
Quemaduras/virología , Infecciones por Citomegalovirus/prevención & control , Monitoreo Fisiológico/métodos , Reacción en Cadena de la Polimerasa de Transcriptasa Inversa/métodos , Viremia/prevención & control , Activación Viral , Anciano , Anciano de 80 o más Años , Sistemas de Computación , Infecciones por Citomegalovirus/etiología , Humanos , Estudios Longitudinales , Persona de Mediana Edad , Carga Viral , Viremia/etiologíaRESUMEN
Successful control of tuberculosis relies on the rapid detection of Mycobacterium tuberculosis. Few chromatographic lateral flow assays for the discrimination of the M. tuberculosis complex were developed from culture media. We compared the values of 2 assays to assess their place in diagnosis of tuberculosis. We conclude of their efficiency and relevance to supplant the conventional methods.