An early literary description of emotional syncope in the Fifth Canto of Dante Alighieri's Commedia: 'E caddi come corpo morto cade'.

Dante's Divine Comedy is universally acclaimed as one of the great masterpieces in world literature. It is written in first person singular and this gives an intimate acquaintance with the vision of the poet. In the Fifth Canto, he exquisitely describes the story of Paolo Malatesta and Francesca da Rimini, illicit lovers killed by Francesca's husband, Gianciotto Malatesta. The story, dramatically told by Francesca, deeply moves the poet, who suddenly faints. In the words of Dante himself: 'E caddi come corpo morto cade' (And fell, even as a dead body falls). This probably is the first literary description of an emotional syncope in world literature. We found that three great plastic artists (John Flaxman, William Blake and Gustave Doré) captured the crucial moment of the syncope in three extraordinary images left for posterity.

The articles of Babinski on his sign and the paper of 1898.

In 1896 Joseph François Felix Babinski described for the first time the phenomenon of the toes; nevertheless in this first paper he simply described extension of all toes with pricking of the sole of the foot. It was not until the second paper of 1898 that he specifically described the extension of the hallux with strong tactile stimulation (stroking) of the lateral border of the sole. Babinski probably discovered his sign by a combination of chance observation and careful re-observation and replication. He also had in mind practical applications of the sign, particularly in the differential diagnosis with hysteria and in medico-legal areas. Several of the observations and physiopathological mechanisms proposed by Babinski are still valid today, e.g, he realized since 1896 that the reflex was part of the flexor reflex synergy and observed that several patients during the first hours of an acute cerebral or spinal insult had absent extensor responses. He also found that most patients with the abnormal reflex had weakness of dorsiflexion of the toes and ankles and observed a lack of correlation between hyperactive myotatic reflexes and the presence of an upgoing hallux. He discovered that not all patients with hemiplegia or paraplegia had the sign but thought erroneously that some normal subjects could have an upgoing toe. Between 1896 and 1903 Babinski continued to think on the sign that bears his name and enrich its semiological and physiopathological value.