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Breast Dis ; 38(2): 47-55, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-31256114

RESUMEN

INTRODUCTION: Inflammatory Breast Cancer (IBC) is a distinct and rare type of breast cancer accounting for up to 6% of all breast cancer cases in Europe. The aim of this study was to investigate diagnostic methods, treatments, and outcome after IBC in patients treated at a single institution in Denmark. METHOD: All patients treated for IBC at Aarhus University Hospital between 2000 and 2014 were identified and included in the cohort. Survival was assessed using Kaplan-Meier curves and log-rank statistics. RESULTS: A total of 89 patients were identified with a median follow up of 3.6 years. The overall survival at 5 and 10 years were 41% and 18%, respectively. The disease free survival at 5 and 10 years were 47% and 27%, respectively. Thirty-four percent had distant metastasis at time of diagnosis. Patients with ER positive tumors had a significantly better overall survival than patients with ER negative tumors (p = 0.01). CONCLUSION: Despite a more aggressive systemic and loco-regional treatment today, IBC is still a very serious disease with a high mortality.


Asunto(s)
Neoplasias Inflamatorias de la Mama/diagnóstico por imagen , Neoplasias Inflamatorias de la Mama/tratamiento farmacológico , Sistema de Registros , Adulto , Anciano , Anciano de 80 o más Años , Biomarcadores de Tumor/genética , Biopsia con Aguja , Dinamarca/epidemiología , Supervivencia sin Enfermedad , Femenino , Humanos , Neoplasias Inflamatorias de la Mama/epidemiología , Neoplasias Inflamatorias de la Mama/secundario , Imagen por Resonancia Magnética , Mamografía , Persona de Mediana Edad , Metástasis de la Neoplasia , Receptores de Estrógenos/genética , Estudios Retrospectivos , Piel/patología , Tasa de Supervivencia
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