An examination of acute physiological and perceptual responses following blood flow restriction exercise using a traditional research device or novel, automated system.

Objective. To compare the acute physiological and perceptual responses to blood flow restriction (BFR) exercise using a traditional research device or novel, automated system.Methods. Forty-four resistance trained individuals performed four sets of unilateral elbow flexion exercise (30% one-repetition maximum) to volitional failure using two distinct restrictive devices [SmartCuffs PRO BFR Model (SMARTCUFF), Hokanson E20 Rapid Inflation device (HOKANSON)] and with two levels of BFR [40% limb occlusion pressure (LOP), 80% LOP]. Blood pressure (BP), muscle thickness (MT), and isometric strength (ISO) were assessed prior to and following exercise. Perceptual responses [ratings of perceived exertion (RPE), discomfort] were assessed prior to exercise and following each exercise set.Main results. Data are displayed as means (SD). Immediately following exercise with 40% LOP, there were no statistical differences between devices for BP, MT, and ISO. However, only following Set 1 of exercise, RPE was greater with SMARTCUFF compared to HOKANSON (p< 0.05). In addition, only following Set 2 of exercise, discomfort was greater with HOKANSON compared to SMARTCUFF (p< 0.001). Immediately following exercise with 80% LOP, there were no statistical differences between devices for BP, MT, and ISO. However, only following Set 4 of exercise, RPE was greater with HOKANSON compared to SMARTCUFF (p< 0.05). In addition, following all exercise sets, discomfort was greater with HOKANSON compared to SMARTCUFF (p< 0.001). For repetitions completed with 40% LOP there were no statistical differences between SMARTCUFF and HOKANSON across any exercise sets. For repetitions completed with 80% LOP there were no statistical differences between SMARTCUFF and HOKANSON across Set 1 of exercise (p= 0.34), however, for Sets 2-4 of exercise, significantly greater number of repetitions were completed during SMARTCUFF than HOKANSON.Significance. The present study provides valuable insight into the efficacy of a novel, automated BFR system (SMARTCUFF) eliciting comparable acute physiological responses to BFR exercise and in some cases favorable perceptual responses when compared to a traditional research device (HOKANSON).

Lower limb blood flow occlusion increases systemic pressor response without increasing brachial arterial blood flow redistribution in women.

This study was conducted to investigate the systemic hemodynamic and vascular changes in women during and after two commonly used clinical blood flow restriction (BFR) pressures at rest. There are minimal data regarding the independent effects of BFR on hemodynamic and systemic vascular changes due to pressor response, particularly among women. Therefore, this study investigated BFR-induced alterations in pressor response and systemic flow redistribution at rest during two commonly used pressures (50% and 80% limb occlusion pressure [LOP]). Fifteen women (22.1 ± 4.2 years) completed two randomised sessions involving 8-min of bilateral, lower limb restriction at 50% or 80% LOP followed by 8-min of recovery post-deflation. Changes in vascular (arterial diameter [DIA], time-averaged mean velocity [TAMV], volume flow [VF], and area) and hemodynamic (heart rate [HR] and blood pressure) measures over time (pre-, during, post-occlusion) and by session (50% vs. 80% LOP) were tested using repeated measures analysis of variance. Repeated measures correlations (rrm) quantified common intraindividual associations between BFR-induced hemodynamic and vascular responses. HR increased from baseline during 50% LOP and remained elevated during recovery (p < 0.05). HR increased from baseline during 80% LOP, while tibial VF and TAMV decreased (p < 0.03 for all). HR and TAMV values returned to baseline during recovery, while brachial artery VF decreased (p < 0.05). Changes in HR, brachial VF, and brachial TAMV were similar between 50% and 80% LOP (rrm = 0.32-0.70, p < 0.05 for all). At 80% LOP, changes in HR were positively correlated with brachial VF (rrm = 0.38) and TAMV (rrm = 0.43) and negatively correlated with tibial VF (rrm = -0.36) and TAMV (rrm = -0.30) (p < 0.05 for all). Results suggest that BFR at 80% LOP elicits an acute systemic pressor reflex without concomitant increases in brachial arterial flow, while 50% LOP elicits a subdued response.

Skeletal muscle mass in competitive physique-based athletes (bodybuilding, 212 bodybuilding, bikini, and physique divisions): A case series.

OBJECTIVES: (1) To examine the muscle thickness of various muscle groups of the body to estimate the absolute and relative skeletal muscle mass (SM) in competitive physique-based athletes (Bodybuilding, 212 Bodybuilding, Bikini, and Physique divisions) and (2) to compare values across various divisions of competition and to resistance trained and non-resistance trained individuals. METHODS: Eight competitive physique-based athletes (2 M and 6 F), two recreationally resistance trained (1 M and 1 F) and two non-resistance trained (1 M and 1 F) participants had muscle thickness measured by ultrasound at nine sites on the anterior and posterior aspects of the body. SM was estimated from an ultrasound-derived prediction equation and SM index was used to adjust for the influence of standing height (i.e., divided by height squared). RESULTS: SM values ranged from 19.6 to 60.4 kg in the eight competitive physique-based athletes and 16.1 to 32.6 kg in the four recreationally resistance trained and non-resistance trained participants. SM index ranged from 7.2 to 17.9 kg/m2 in the eight competitive physique-based athletes and 5.8 to 9.3 kg/m2 in the four recreationally resistance trained and non-resistance trained participants. CONCLUSION: Overall, varying magnitudes of SM and SM index were present across competitors and their respective divisions of bodybuilding. The Men's Open Bodybuilder in the present study had greater values of total SM and SM index compared to previously published values in the literature. Our data provides insight into the extent of SM present in this population and further extends the discussion regarding SM accumulation in humans.

Muscular Adaptations Between Very Low Load Resistance Training With Pulsed Direct Current Stimulation (Neubie) and Traditional High Load Training.

OBJECTIVES: This study compared muscle growth in response to very low load resistance training with direct pulsed current (DPC) stimulation and traditional high load training. METHODS: Twenty-six resistance trained individuals had each leg assigned to one of two unilateral knee extension protocols: 1) 4 sets of 20 repetitions at ~10% one-repetition maximum (1RM) and inter-set rest periods of 30 s (DPC) and 2) 4 sets to muscular failure at ~70% 1RM (TRAD). Muscle thickness (MTH), 1RM strength, and local muscular endurance (LME) were measured before and after 8-weeks of training. An alpha level of 0.05 was used for all comparisons. RESULTS: MTH increased similarly between TRAD and DPC at the 50% (0.24 cm, 95%CI: 0.11-0.36), and the 60% anterior sites (0.25 cm, 95%CI: 0.10-.040), as well as the lateral (0.25 cm, 95%CI: 0.10-.040) and medial sites (0.21 cm, 95%CI: 0.10-0.31), but was greater for TRAD at the 40% anterior site (0.3 cm, 95%CI: 0.16-0.43). Changes in 1RM were greater for TRAD (10.2 kg, 95%CI: 5.8-14.4). LME increased similarly between protocols (5 repetitions, 95%CI: 3-7). CONCLUSIONS: The current data suggest that very low load knee extension resistance training with DPC could be a viable training strategy for promoting skeletal muscle growth and local muscular endurance.

Skeletal Muscle Adaptations to High-Load Resistance Training With Pre-Exercise Blood Flow Restriction.

ABSTRACT: Hammert, WB, Moreno, EN, Martin, CC, Jessee, MB, and Buckner, SL. Skeletal muscle adaptations to high-load resistance training with pre-exercise blood flow restriction. J Strength Cond Res 37(12): 2381-2388, 2023-This study aimed to determine if blood flow restriction (BFR) could augment adaptations to a high-load training protocol that was inadequate for muscle growth. Forty nontrained individuals had each arm assigned to 1 of 3 elbow flexion protocols: (a) high-load resistance training [TRAD; 4 sets to muscular failure at 70% 1 repetition maximum (1RM)], (b) low repetition high-load resistance training with pre-exercise BFR (PreBFR; 4 sets of 3 repetitions at 70% 1RM + 3 min of pre-exercise BFR), and (c) low repetition high-load resistance training (LRTRAD); 4 sets of 3 repetitions at 70% 1RM). Muscle thickness (MT), 1RM strength, and local muscular endurance (LME) of the elbow flexors were measured before and after 8 weeks. An alpha level of 0.05 was used for all comparisons. For the 50% site, MT increased for TRAD (0.211 cm, 95% confidence interval [95% CI]: 0.143-0.280), PreBFR (0.105 cm, 95% CI: 0.034-0.175), and LRTRAD (0.073 cm, 95% CI: 0.000-0.146). The change for TRAD was greater than PreBFR and LRTRAD. For the 60% site, MT increased for TRAD (0.235 cm, 95% CI: 0.153-0.317), PreBFR (0.097 cm, 95% CI: 0.014-0.180), and LRTRAD (0.082 cm, 95% CI: 0.000-0.164). The change for TRAD was greater than PreBFR and LRTRAD. For the 70% site MT increased for TRAD (0.308 cm, 95% CI: 0.247-0.369), PreBFR (0.103 cm, 95% CI: 0.041-0.166), and LRTRAD (0.070 cm, 95% CI: 0.004-0.137). The change for TRAD was greater than PreBFR and LRTRAD. One repetition maximum and LME significantly increased for each condition, with no differences between conditions. Collapsed across conditions 1RM strength increased 2.094 kg (95% CI: 1.771-2.416) and LME increased 7.0 repetitions (95% CI: 5.7-8.3). In conclusion, the application of BFR to low-repetition, high-load training did not enhance the adaptative response.

Acute muscular and cardiovascular responses to high load training with pre-exercise blood flow restriction.

PURPOSE: The purpose of this study is to examine the acute muscular and cardiovascular responses to applying blood flow restriction (BFR) before high-load training. METHODS: Forty trained individuals visited the lab on three occasions. On Visit 1, participants completed paperwork and performed strength assessments. During Visits 2 and 3, participants completed four exercise conditions (one in each arm during each visit) as follows: (1) traditional resistance training (TRAD), (2) low load training with BFR (LLBFR), (3) low repetition high load training with pre-exercise BFR (PreBFR), and (4) low repetition traditional training (LRTRAD). Blood pressure, muscle thickness (MT), and isometric strength (ISO) were measured before and after exercise. RESULTS: Data are displayed as means (SD). Immediately following exercise, MT in TRAD was greater compared with PreBFR (mean difference = 0.18[0.30] cm, p < 0.001) and LRTRAD (mean difference = 0.28[0.30] cm, p < 0.001). In addition, LLBFR demonstrated greater MT compared with PreBFR (mean difference = 0.24[0.30] cm, p < 0.001]. Immediately following exercise, ISO was lower in TRAD compared with PreBFR (mean difference = 33.8[46.9]N, p < 0.001) and the LRTRAD condition (mean difference = 32.8[50.4]N, p < 0.001). In addition, ISO was lower in LLBFR compared with PreBFR (mean difference = 43.9 [47.4]N, p < 0.001) and LRTRAD (mean difference = 42.9 [43.8]N, p < 0.001). Immediately following exercise, systolic blood pressure was greater in TRAD compared with PreBFR and LRTRAD. CONCLUSION: The application of BFR before engaging in high-load training does not seem to augment the muscular responses to exercise when compared with traditional high loads alone; however, it may pose less demand on the cardiovascular system.

Does performing resistance exercise to failure homogenize the training stimulus by accounting for differences in local muscular endurance?

The prescription of resistance exercise often involves administering a set number of repetitions to be completed at a given relative load. While this accounts for individual differences in strength, it neglects to account for differences in local muscle endurance and may result in varied responses across individuals. One way of potentially creating a more homogenous stimulus across individuals involves performing resistance exercise to volitional failure, but this has not been tested and was the purpose of the present study. Individuals completed 2 testing sessions to compare repetitions, ratings of perceived exertion (RPE), muscle swelling and fatigue responses to arbitrary repetition (SET) vs. failure (FAIL) protocols using either 60% or 30% one-repetition maximum. Statistical analyses assessed differences in the variability between protocols. Forty-six individuals (25 females and 21 males) completed the study. There was more variability in the number of repetitions completed during FAIL when compared to SET protocols. Performing the 60% 1RM condition to failure appeared to reduce the variability in muscle swelling (average variance: 60%-SET = .034, 60%-FAIL = .023) and RPE (average variance: 60%-SET = 4.0, 60%-FAIL = 2.5), but did not alter the variability in muscle fatigue. No differences in variability were present between the SET-30% and FAIL-30% protocols for any of the dependent variables. Performing resistance exercise to failure may result in a more homogenous stimulus across individuals, particularly when using moderate to high exercise loads. The prescription of resistance exercise should account for individual differences in local muscle endurance to ensure a similarly effective stimulus across individuals.Highlights There is a large variance in the number of repetitions individuals can complete even when exercising with the same relative load.Ratings of perceived exertion and muscle swelling responses become more homogenous when exercising to volitional failure as compared to using performing a set number of repetitions, particularly when moderate to higher loads are used.The prescription of exercise should take into consideration the individual's local muscle endurance as opposed to choosing an arbitrary number of repetitions to be completed at a given relative load.

Injuries and Strength Training Practices in Collegiate Tennis.

Strength and conditioning practices may influence injury rates in the sport of tennis. Methods: Coaches reported the number injuries over the past year. Coaches were also surveyed on whether their training program included training related to upper-body or lower-body strength, power, muscle growth, and eccentric exercise. Separate regression analyses were run in the upper and lower body to examine the relationship between injuries and participation in training focused on strength, power, growth, and maximal eccentric exercise. A total of 111 coaches were surveyed. The most frequent injuries observed were ankle sprains (144 injures), followed by paraspinal muscle strains (126 injuries). When pooled, there were a total of 355 lower-body and 260 upper-body injuries. Strength and conditioning practices explained 9.9% of the variance of injury rates in the upper body (R2 = 0.099). The only significant predictor of upper-body injury was participation in upper-body muscle growth training (ß = 1.613, p = 0.013). In addition, training practices explained 11.1% of the variance of injury in the lower body (R2 = 0.111). Coaches value injury prevention exercise, sports-specific training and flexibility and mobility training the most, with muscle growth and maximal power ranked lowest. Additionally, the most frequent injuries observed in collegiate tennis players were ankle sprains (144 injures), followed by paraspinal muscle strains (126 injuries).

The acute muscular response following a novel form of pulsed direct current stimulation (Neubie) or traditional resistance exercise.

OBJECTIVES: To examine changes in muscle thickness (MT), soreness (SOR), and isometric torque (ISO) following exercise with pulsed direct current (Neubie) or traditional high-load (TRAD) exercise. METHODS: Thirty-two participants had SOR, MT, and ISO measured before, immediately after, and 24 and 48h following TRAD and Neubie. Rating of perceived exertion (RPE) and discomfort were also measured. Results are displayed as means(SD). RESULTS: For MT, there was a condition x time interaction (p<0.001). For Neubie, MT increased pre [3.7(0.7)cm] to post [3.9(0.8) cm, p<0.001] and remained elevated at 24h. For TRAD, MT increased pre [3.7(0.6)cm] to post [4.0 (0.7)cm, p<0.001] and remained up to 48h. Greater values were observed for TRAD post-exercise. For ISO, both conditions decreased up to 48h. TRAD demonstrated a greater change post exercise (p<0.001). For SOR, both conditions increased up to 48h. Neubie demonstrated greater SOR at 48h (p=0.007). RPE was higher for all sets in TRAD [Mean across sets=16.0(1.9) vs. 13.5(2), p<0.001]. Discomfort was higher in all sets for Neubie [Mean across sets=5.8(1.5)vs. 4.5(2.0), p<0.05]. CONCLUSIONS: Both conditions showed increased SOR, and decreased ISO for up to 48h, with MT increased for up to 24h. MT remained elevated in TRAD at 48h. Neubie training might be effective for individuals who are looking to experience lower RPE responses during exercise.

Sex Differences May Exist for Performance Fatigue but Not Recovery After Single-Joint Upper-Body and Lower-Body Resistance Exercise.

ABSTRACT: Lewis, MH, Siedler, MR, Lamadrid, P, Ford, S, Smith, T, SanFilippo, G, Waddell, B, Trexler, ET, Buckner, S, and Campbell, BI. Sex differences may exist for performance fatigue but not recovery after single-joint upper-body and lower-body resistance exercise. J Strength Cond Res 36(6): 1498-1505, 2022-This study evaluated sex differences in performance recovery and fatigue during dynamic exercise. Twenty-eight resistance-trained males (n = 16) and females (n = 12) completed a repeated-measures, randomized, parallel-groups design. The protocol consisted of a baseline assessment, a recovery period (4, 24, or 48 hours), and a postrecovery assessment. The assessments were identical consisting of 4 sets of 10 repetition maximum (10RM) bicep curls and 4 sets of 10RM leg extensions to failure. Recovery was quantified as the number of total repetitions completed in the postrecovery bout. Fatigue was quantified as the number of repetitions completed set to set within the session. For analysis, we set the level of significance at p ≤ 0.05. No sex differences in performance recovery were observed across any of the investigated time periods for either exercise modality. Regarding fatigue, significant effects were observed for set (p < 0.001) and sex (p = 0.031) for bicep curls. Repetitions dropped in later sets, and females generally completed a greater number of repetitions than males (8.8 ± 0.5 vs. 7.2 ± 0.5). For leg extension, a significant sex × set interaction was observed (p = 0.003), but post hoc tests revealed these sex differences as marginal. Our results suggest that in dynamic bicep curls and leg extensions, other factors unrelated to sex may be more impactful on performance recovery. To optimize an athlete's desired adaptations, it may be more important to consider other variables unrelated to sex such as volume, perceived exertion, and training history when formulating training prescriptions for single-joint exercises.

Muscle growth adaptations to high-load training and low-load training with blood flow restriction in calf muscles.

PURPOSE: To compare muscle growth adaptations between traditional high-load training and low-load training with blood flow restriction (BFR) in the calf muscles over 6 weeks. METHODS: 27 trained individuals performed calf exercise in both legs for 6 weeks. Each leg was randomly assigned to one of the two conditions: (1) Traditional (70% of 1RM) training (TRAD); and (2) Low-load (30% of 1RM) training with BFR. In addition, subjects performed standing calf raises with or without BFR. Measures were taken pre- and post-intervention. RESULTS: For the posterior muscle site, there was no condition (BFR vs. TRAD) × time (pre vs. post) interaction (p = 0.15). In addition, there was no main effect for condition (p = 0.83) or time (p = 0.20). For the lateral muscle site, there was no condition × time interaction (p = 0.47). In addition, there was no main effect for condition (p = 0.10) or time (p = 0.57). For the medial muscle site, there was no condition × time interaction (p = 0.60). In addition, there was no main effect for condition (p = 0.44) or time (p = 0.72). For RPE, there was no condition × time interaction. However, there was a main effect for condition (p < 0.05) with BFR having higher RPE. For discomfort, there was no condition × time interaction. However, there was a main effect for condition (p < 0.001) with the BFR condition displaying higher discomfort. CONCLUSION: No muscle growth was detected in the calf musculature. BFR was not more effective at eliciting muscle hypertrophy compared to traditional training. However, it was accompanied with higher exertion and discomfort.

Examination of Changes in Echo Intensity Following Resistance Exercise among Various Regions of Interest.

AIM: Within the resistance exercise literature, echo intensity (EI) is often quantified using different regions of interest (ROI). PURPOSE: To compare changes in the EI of images of the biceps muscle using different ROI immediately following exercise as well as 24 and 48 h following exercise. METHODS: Twenty seven non-resistance trained individuals visited the laboratory 4 times. One arm was assigned to the experimental condition, and the other was a non-exercise control. During visit 1, paperwork and strength were measured. During visit, 2 participant's muscles were imaged before performing biceps curls. Additional muscle images were taken immediately after exercise, as well as 24 and 48 h post. EI was measured using three different ROI: 1) Trace around the entire muscle; 2) Small box placed in the middle of the muscle (2 × 2cm); and 3) Maximal rectangular box. Results are displayed as means (95%CI). RESULTS: There was no condition (experimental vs. control) x time (pre, post, 24h and 48h) x box size (small, large, full trace) interaction (p = 0·592). However, there was a main effect for box size (p < 0·001). EI values were higher with the small box [28·2 (23·3, 33·1) AU] compared to the large box [26·8 (22·3, 31·2) AU, p = 0·016] and compared to the full trace [24·2 (20·3, 28·0) AU p < 0·001)]. In addition, EI values were higher with the large box compared to the full trace technique (p = 0·001). CONCLUSION: Similar changes in EI are detected when using different commonly used ROI for analysing EI. However, when larger ROI are examined, EI values appear to be lower.

Is there Evidence for the Suggestion that Fatigue Accumulates Following Resistance Exercise?

It has been suggested that improper post-exercise recovery or improper sequence of training may result in an 'accumulation' of fatigue. Despite this suggestion, there is a lack of clarity regarding which physiological mechanisms may be proposed to contribute to fatigue accumulation. The present paper explores the time course of the changes in various fatigue-related measures in order to understand how they may accumulate or lessen over time following an exercise bout or in the context of an exercise program. Regarding peripheral fatigue, the depletion of energy substrates and accumulation of metabolic byproducts has been demonstrated to occur following an acute bout of resistance training; however, peripheral accumulation and depletion appear unlikely candidates to accumulate over time. A number of mechanisms may contribute to the development of central fatigue, postulating the need for prolonged periods of recovery; however, a time course is difficult to determine and is dependent on which measurement is examined. In addition, it has not been demonstrated that central fatigue measures accumulate over time. A potential candidate that may be interpreted as accumulated fatigue is muscle damage, which shares similar characteristics (i.e., prolonged strength loss). Due to the delayed appearance of muscle damage, it may be interpreted as accumulated fatigue. Overall, evidence for the presence of fatigue accumulation with resistance training is equivocal, making it difficult to draw the conclusion that fatigue accumulates. Considerable work remains as to whether fatigue can accumulate over time. Future studies are warranted to elucidate potential mechanisms underlying the concept of fatigue accumulation.

Do exercise-induced increases in muscle size contribute to strength in resistance-trained individuals?

AIM: Previous work in non-resistance-trained individuals has found that an increase in muscle size has no additive effect on changes in strength. However, it is thought that muscle growth is of increased importance for resistance-trained individuals. PURPOSE: Experiment 1: To examine changes in muscle thickness (MT) and one repetition maximum (1RM) strength following 8 weeks of bi-weekly 1RM practice or traditional training. Experiment 2: To determine whether increasing muscle size increases strength potential when followed by 4 weeks of 1RM training. METHODS: Participants performed biceps curls for 8 weeks (Experiment 1). One arm performed 4 sets of as many repetitions as possible with approximately 70% of 1RM (TRAD), and the other arm performed a single 1RM. For experiment 2, both arms trained for muscle size and strength. RESULTS: Experiment 1 (n = 25): for MT, the posterior probabilities favoured the hypothesis that MT changed more in the TRAD condition [mean difference: 50% site 0.15 (-0.09, 0.21) cm; 60% site 0.14 (0.06, 0.23) cm; 70% site 0.17 (0.10, 0.23) cm]. For 1RM strength, each condition changed equivalently. Experiment 2 (n = 18): for MT, the posterior probabilities favoured the hypothesis that MT changed similarly between conditions following a 4-week strength phase. For changes in 1RM strength, the evidence favoured neither hypothesis (i.e. null vs. alternative). Of note, the mean difference between conditions was small [0.72 (4.3) kg]. CONCLUSIONS: 1RM training produces similar increases in strength as traditional training. Experiment 2 suggests that increases in muscle mass may not increase the 'potential' for strength gain.

Periodization: Variation in the Definition and Discrepancies in Study Design.

Over the past several decades, periodization has been widely accepted as the gold standard of training theory. Within the literature, there are numerous definitions for periodization, which makes it difficult to study. When examining the proposed definitions and related studies on periodization, problems arise in the following domains: (1) periodization has been proposed to serve as the macro-management of the training process concerning the annual plan, yet research on long-term effects is scarce; (2) periodization and programming are being used interchangeably in research; and (3) training is not periodized alongside other stressors such as sport (i.e., only resistance training is being performed without the inclusion of sport). Overall, the state of the literature suggests that the inability to define periodization makes the statement of its superiority difficult to experimentally test. This paper discusses the proposed definitions of periodization and the study designs which have been employed to examine the concept.

An examination of changes in muscle thickness, isometric strength and body water throughout the menstrual cycle.

PURPOSE: The purpose of this study was to examine the changes in muscle size and strength throughout the menstrual cycle in females and to compare these values to a control group of time-matched males. METHODS: 12 males and 16 females visited the laboratory on four occasions. Measures of muscle thickness (MTH), isometric strength and body water were taken during the menstrual phase, ovulation phase and luteal phase of the menstrual cycle. Males scheduled their visits based on a mock menstrual cycle. In addition, participants were asked to complete 4 sets of biceps curls to volitional failure in one arm to examine swelling during each visit. RESULTS: For MTH there was no interaction (p = .73); however, there was a main effect for sex with males having higher MTH values compared to females [4.07 (0.67) versus. 2.73 (0.42) cm, (p < .001)] at all time points. For changes in MTH (swelling) there was no interaction (p = .28). However, there was a main effect for sex, with males demonstrating greater changes in MTH compared to females [0.53(0.11) versus. 0.40 (0.10) cm, (p < .001)]. Similarly, for total body water, there was no interaction (p = .66). However, males had greater total body water compared to females [49.6 (6.8) versus. 32.3(3.9) kg, p < .001)] at all time points. Finally, for isometric strength, there was no interaction (p = .23). However, there was a main effect for sex. Males had higher isometric strength values compared to females [285 (42) versus. 156(36) N (p < .001)]. CONCLUSIONS: Phase of the menstrual cycle does not appear to influence MTH, isometric strength or total body water.

Strength testing or strength training: considerations for future research.

Maximal strength testing is often performed to assess the efficacy of training programs or as a way to prescribe exercise load. Generally, it is believed that high load exercise is superior to low load exercise at increasing absolute strength, however this is not always the case (i.e. strength increases similarly between groups). We hypothesized that some of the discrepancy in the literature may be related to performing the strength test itself. To investigate this further we reviewed the literature looking for studies comparing high load and low load exercise. The included studies were separated into 'no extra practice' and 'practice'. No extra practice means the strength test was only performed at pre and post whereas practice refers to additional strength tests performed throughout the training intervention. Our results indicated that the differences between high load and low load exercise can be reduced when the group training with a low load is allowed additional exposure to the maximal strength test. This suggests that repeated exposure to strength tests may augment low load training adaptations and influence the outcomes. We discuss potential moderators of this relationship (e.g. how low is the low load, complexity of the skill) and offer considerations for future research. Based on this it would be recommended that when investigating the effects of low load training strength tests should be limited to pre and post intervention or if a control group is utilized then the control group should receive the same number of exposures to the strength test.

The acute muscular response to passive movement and blood flow restriction.

PURPOSE: To compare the acute effects of passive movement combined with blood flow restriction (PM + BFR) to passive movement (PM) or blood flow restriction alone (BFR). METHODS: A total of 20 healthy participants completed: time control (TC), PM, BFR and PM + BFR (one per leg, over 2 days; randomized). For PM, a dynamometer moved the leg through 3 sets of 15 knee extensions/flexions (90° at 45°/second). For BFR, a cuff was inflated to 80% arterial occlusion pressure on the upper leg. Measurements consisted of anterior muscle thickness at 60% and 70% of the upper leg before and after (-0, -5 and -10 min) conditions, ratings of perceived effort and discomfort before conditions and after each set, and of the vastus lateralis during conditions. Data, presented as mean (SD), were compared using Bayesian RMANOVA, except for perceived effort and discomfort, which were compared using a Friedman's test (non-parametric). RESULTS: 60% (Δcm before-after-0: TC = 0.04 [0.09], PM = -0.01 [0.15], BFR = 0.00 [0.11], PM + BFR = 0.01 [0.22]) and 70% (Δcm before-after-0: TC = 0.01 [0.09], PM = -0.01 [0.15], BFR = 0.02 [0.11], PM + BFR = -0.03 [0.22]) muscle thickness did not change. Perceived effort was greater than TC following PM (p = .05) and PM + BFR (p = .001). Perceived discomfort was greater following BFR and PM + BFR compared to TC (all p ≤ .002) and PM (all p ≤ .010). Changes in deoxygenation (e.g. channel 1; ΔµM start set 1-end set 3: TC = 0.9 [1.2], PM = -1.2 [1.9], BFR = 10.3 [2.7], PM + BFR = 10.3 [3.0]) were generally greater with BFR and PM + BFR (BFinclusion  = 1.210e + 13). CONCLUSION: Acute muscular responses to PM + BFR are not augmented over the effect of BFR alone.