1.
Epidemiol Prev
; 13(48-49): 155-7, 1991.
Artículo
en Italiano
| MEDLINE
| ID: mdl-1843300
Asunto(s)
Diabetes Mellitus/epidemiología , Adulto , Factores de Edad , Anciano , Femenino , Humanos , Incidencia , Italia/epidemiología , Masculino , Persona de Mediana Edad , Prevalencia , Factores de Riesgo , Factores Sexuales
2.
G Ital Cardiol
; 17(9): 781-5, 1987 Sep.
Artículo
en Italiano
| MEDLINE
| ID: mdl-3319758
RESUMEN
Two cases of 5-Fluorouracil (5FU) cardiotoxicity, chest pain with changes in ECG the former, and myocardial infarction the latter, are described. Review of literature shows the existence of 49 cases of cardiotoxicity due to 5FU (38 angina = 77.5% 8 myocardial infarction = 16.3%). This complication seems due to a "coronary toxicity" whose onset is very precocious and not dose-dependent. Since 5FU therapy could result very dangerous when cardiotoxicity occurs, it is strictly advisable to withdraw further administration of the drug. As a matter of fact 18 patients out of 21 who again were treated with 5FU, had more serious complications which resulted in 3 myocardial infarctions (2 deaths).