RESUMEN
Contemporary diagnosis and management of traumatic dental injuries requires a multifaceted understanding of the pathological and psychological impact over a patient's lifetime. The legacy of dental trauma injuries can have repercussions for the dentition and supporting tissues, requiring complicated multidisciplinary clinical input. Foresight is required to ensure optimal aesthetic and functional outcomes. Mitigating risks and maximising benefits in patients presenting with polytrauma can be challenging, but if optimally managed at the acute presentation, the long-term burden to the patient and the clinician is reduced. This paper aims to discuss the contemporary clinical dilemmas, challenges and controversies related to the management of dental trauma.
Asunto(s)
Estética Dental , Traumatismos de los Dientes , Humanos , Traumatismos de los Dientes/terapiaRESUMEN
Acute dental trauma is unscheduled and presents infrequently to the majority of practitioners. Therefore, a consistent, logical and systematic process for examination, prioritisation and management is imperative for all sustained injuries to have an optimal outcome. Fractures are a frequent sequela to dental trauma and can involve any aspect of the tooth structure or supporting alveolar bone. While some minor crown fractures may initially seem inconsequential, they may be a subtle indication to a more serious underlying root fracture. Concomitant injuries and injuries that have been initially missed are generally associated with poorer outcomes. The time sensitive management of traumatic dental injuries aims to preserve pulpal and periodontal health where possible. The follow up period for tooth or alveolar fractures are important to allow for early intervention if pathology develops.
Asunto(s)
Avulsión de Diente , Fracturas de los Dientes , Humanos , Avulsión de Diente/complicaciones , Raíz del Diente/lesiones , Corona del Diente/lesiones , Fracturas de los Dientes/diagnóstico , Fracturas de los Dientes/terapia , Fracturas de los Dientes/complicaciones , Pulpa Dental/lesionesRESUMEN
Peg-shaped and missing lateral incisor teeth are common features for patients affected by hypodontia. While improvements in dental appearance may be a strong motivating factor for these patients, providing dental treatment to improve the clinical condition and achieve an acceptable and stable outcome can be complex and lengthy.For patients affected by hypodontia, discussion and consideration of various approaches to their individual treatment are best achieved in a multidisciplinary team environment. This allows debate of options and joint agreement between at least orthodontic and restorative dentistry specialist colleagues, based largely on clinical factors, towards a treatment plan that is acceptable to the patient. As most patients with this lateral incisor form of hypodontia are initially treated as teenagers and young adults, there is also an understanding that treatment outcomes will have lifelong maintenance and resource implications to consider.This paper identifies and discusses the key clinical features that influence the treatment planning process for a patient with either missing or peg lateral incisor teeth. These will often involve consideration of whether to open or close the lateral incisor spaces and whether to restore or replace a peg lateral incisor tooth. The process should be patient-centred, evidence-based, and aim to minimise the lifelong treatment burden, retaining options for future maintenance and retreatment.
Asunto(s)
Anodoncia , Adolescente , Adulto Joven , Humanos , Anodoncia/terapia , Incisivo , Maxilar , Odontología , Resultado del TratamientoRESUMEN
Diagnosis, disease control and prevention are the precursors to successful definitive restorative treatment of pathological tooth wear. This case series illustrates how proposed key clinical features can influence treatment complexity and provide the clinician with a logical sequence of treatment options for definitive management of tooth wear.
Asunto(s)
Atrición Dental , Desgaste de los Dientes , Humanos , Desgaste de los Dientes/terapia , Desgaste de los Dientes/diagnóstico , Planificación de Atención al PacienteRESUMEN
AIMS: Periodontal diseases negatively affect implant osseointegration. Perturbations in non-neuronal cholinergic signalling mechanisms are associated with periodontitis; however, their role in generalized aggressive periodontitis (GAgP) is unknown. The aim of this prospective case-control study was to determine the relationship between non-neuronal cholinergic signalling mechanisms, secreted Ly-6/uPAR-related protein-1 (SLURP-1), interleukin-17 (IL-17) family cytokines and healing of dental implants in health and GAgP. MATERIAL AND METHODS: Thirteen GAgP patients and seven periodontally healthy individuals (PH) were recruited. Peri-implant crevicular fluid (PICF) was obtained at baseline and 1 month post-placement. Acetylcholine (ACh) levels and cholinesterase activity were determined biochemically. SLURP-1, IL-17A and IL-17E levels were determined by ELISA. Marginal bone loss (MBL) at 1 and 6 months post-placement was determined radiographically. RESULTS: The concentration of ACh, cholinesterase activity and IL-17A levels was elevated in PICF of patients with GAgP compared to PH individuals at baseline and 1 month post-placement. The concentration of ACh and cholinesterase activity levels in PICF correlated with levels of IL-17A and MBL around implants 1 month post-placement in patients with GAgP. CONCLUSIONS: Non-neuronal cholinergic mechanisms may play a role in the aetiopathogenesis of GAgP and may directly or indirectly, through modulation of IL-17A, influence early implant osseointegration and potential long-term implant survival.
Asunto(s)
Periodontitis Agresiva , Implantes Dentales , Estudios de Casos y Controles , Colinérgicos , Líquido del Surco Gingival , Humanos , Estudios ProspectivosRESUMEN
BACKGROUND: Evidence to support the role of Candida species in oral disease is limited. Often considered a commensal, this opportunistic yeast has been shown to play a role in denture related disease, though whether it is an active participant or innocent bystander remains to be determined. This study sought to understand the role of Candida species alongside the bacterial microbiome in a denture patient cohort, exploring how the microbiology of the denture was affected by oral hygiene practices. MATERIALS AND METHODS: In vitro denture cleansing studies were performed on a complex 9-species interkingdom denture biofilm model, with quantitative assessment of retained bacterial and fungal viable bioburdens. Patient hygiene measures were also collected from 131 patients, including OHIP, frequency of denture cleansing, oral hygiene measure and patient demographics. The bacterial microbiome was analysed from each patient, alongside quantitative PCR assessment of ITS (fungal) and 16S (bacterial) bioburden from denture, mucosa and intact dentition. RESULTS: It was shown that following in vitro denture cleansing C. albicans were unresponsive to treatment, whereas bacterial biofilms could repopulate 100-fold, but were susceptible to subsequent treatment. Within the patient cohort, oral hygiene did not impact candidal or bacterial composition, nor diversity. The levels of Candida did not significantly influence the bacterial microbiome, though an observed gradient was suggestive of a microbial composition change in response to Candida load, indicating interkingdom interaction rather than an oral hygiene effect. Indeed, correlation analysis was able to show significant correlations between Candida species and key genera (Lactobacillus, Scardovia, Fusobacterium). CONCLUSIONS: Overall, this study has shown that the denture microbiome/mycobiome is relatively resilient to oral hygiene challenges, but that Candida species have potential interactions with key oral genera. These interactions may have a bearing on shaping community structure and a shift from health to disease when the opportunity arises.
RESUMEN
Approximately 20 % of the UK population wear some form of denture prosthesis, resulting in denture stomatitis in half of these individuals. Candida albicans is primarily attributed as the causative agent, due to its biofilm -forming ability. Recently, there has been increasing evidence of C. albicans biofilm heterogeneity and the negative impact it can have clinically; however, this phenomenon has yet to be studied in relation to denture isolates. The aims of this study were to evaluate C. albicans biofilm formation of clinical denture isolates in a denture environment and to assess antimicrobial activity of common denture cleansers against these tenacious communities. C. albicans isolated from dentures of healthy and diseased individuals was quantified using real-time PCR and biofilm biomass assessed using crystal violet. Biofilm development on the denture substratum poly(methyl methacrylate), Molloplast B and Ufi-gel was determined. Biofilm formation was assessed using metabolic and biomass stains, following treatment with denture hygiene products. Although C. albicans was detected in greater quantities in diseased individuals, it was not associated with increased biofilm biomass. Denture substrata were shown to influence biofilm biomass, with poly(methyl methacrylate) providing the most suitable environment for C. albicans to reside. Of all denture hygiene products tested, Milton had the most effective antimicrobial activity, reducing biofilm biomass and viability the greatest. Overall, our results highlight the complex nature of denture- related disease, and disease development cannot always be attributed to a sole cause. It is the distinct combination of various factors that ultimately determines the pathogenic outcome.
Asunto(s)
Biopelículas , Candida albicans/crecimiento & desarrollo , Limpiadores de Dentadura/farmacología , Dentaduras/microbiología , Estomatitis Subprotética/microbiología , Antifúngicos/farmacología , Candida albicans/efectos de los fármacos , Estudios de Casos y Controles , Recuento de Colonia Microbiana , Humanos , Viabilidad Microbiana/efectos de los fármacos , Polimetil Metacrilato/química , Reacción en Cadena en Tiempo Real de la Polimerasa , Propiedades de Superficie/efectos de los fármacosRESUMEN
INTRODUCTION: It is widely accepted that the permanent maxillary central incisor almost invariably has a single canal. METHODS AND RESULTS: This case reports a maxillary central incisor canal morphology that differs from this predominant form, a single-rooted permanent maxillary central incisor with 1 main canal that separated into 2 distinct canals in the apical third with 2 apical foramina. The presence of a superimposed mesioden was also established. Nonsurgical endodontic retreatment achieved an optimal result. CONCLUSIONS: There is greater variation in root canal morphology of permanent maxillary central incisors than population studies would suggest.
Asunto(s)
Variación Anatómica , Cavidad Pulpar/diagnóstico por imagen , Incisivo/diagnóstico por imagen , Estudios de Seguimiento , Humanos , Masculino , Maxilar , Persona de Mediana Edad , Periodontitis Periapical/diagnóstico por imagen , Radiografía , Retratamiento , Ápice del Diente/anatomía & histología , Ápice del Diente/diagnóstico por imagen , Diente no Vital/diagnóstico por imagen , Diente Supernumerario/diagnóstico por imagenRESUMEN
DESIGN: Randomised controlled trial. INTERVENTION: Edentulous patients aged at least 18 years with lack of retention and stability of the upper denture and lower denture were randomised to receive a maxillary overdenture supported by either four or six bar-connected implants. OUTCOME MEASURE: The primary outcome measure was change of radiographic bone level. Secondary outcome measures were implant survival, overdenture survival and soft tissue conditions (plaque index, presence of calculus, gingiva index, sulcus bleeding index and pocket probing depth). These were scored at placement of the overdenture and after 12 months of loading. Patient satisfaction was also scored at baseline and at 12 months. RESULTS: Forty-nine patients (one drop out) completed the one year follow-up. Mean marginal bone resorption was 0.24 ± 0.32 mm in the four implants group and 0.25 ± 0.29 mm in the six implants group. Implant survival was 100% in the four implants group and 99.3% in the six implants group (one implant lost). Overdenture survival was 100% in both groups. There were no differences in the soft tissue outcomes between the groups. Patient satisfaction had improved in both groups. CONCLUSIONS: After one year a bar-connected maxillary overdenture on four or six implants results in a comparable treatment outcome with high implant survival, healthy peri-implant tissues and high patient satisfaction. For reasons of cost-effectiveness, treatment with four bar-connected implants to support a maxillary overdenture is preferred.