Diastereoselective additions of H-phosphinates to alkenyl ketones under phase-transfer conditions.

Additions of bulky H-phosphinates to ß,ß-disubstituted alkenyl ketones under the action of a phase transfer-catalyst led to a new class of carbon quaternary center-containing phosphinates with unprecedented control of the relative configuration of the adjacent carbon and phosphorous chiral centers with high diastereoselectivity in most cases.