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Isr Med Assoc J ; 23(10): 662-664, 2021 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-34672450

RESUMEN

BACKGROUND: Iron deficiency anemia is a widespread problem. Although oral and intravenous therapy are available, iron malabsorption is a distinct possibility. OBJECTIVES: To evaluate the applicability of the oral iron absorption test (OIAT) as a simple and effective means of determining the degree of oral iron absorption. METHODS: The study comprised 81 patients diagnosed with iron deficiency anemia who were referred to a hematology outpatient clinic. Participants were given two ferrous sulphate tablets. Iron levels in the blood were evaluated at intervals from 30 to 180 minutes after iron administration. RESULTS: We divided patients into three distinct groups. The first group consisted of patients with little iron absorption with a maximum iron increment (Cmax) in the blood of 0-49 ug/dl. The second group had a moderate maximum absorption of 50-100 ug/dl, while a third group had considerable absorption of with maximum iron increase of over 100 ug/dl. CONCLUSIONS: The oral iron absorption test, although not clearly standardized, is easy to conduct in any outpatient clinic. This test can readily and clearly determine absorption or nonabsorption of iron. This test can have major implications on the need of oral or intravenous iron therapy and can also determine the need for further gastrointestinal evaluation of the small intestine, where iron absorption takes place and the success of therapy on subsequent iron absorption.


Asunto(s)
Administración Oral , Anemia Ferropénica , Monitoreo de Drogas/métodos , Compuestos Ferrosos , Anemia Ferropénica/diagnóstico , Anemia Ferropénica/tratamiento farmacológico , Anemia Ferropénica/fisiopatología , Disponibilidad Biológica , Femenino , Compuestos Ferrosos/administración & dosificación , Compuestos Ferrosos/sangre , Absorción Gastrointestinal/fisiología , Hematínicos/administración & dosificación , Hematínicos/sangre , Humanos , Síndromes de Malabsorción/diagnóstico , Masculino , Persona de Mediana Edad , Reproducibilidad de los Resultados
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