Bilateral pleural metastases of a primary central nervous system neuroblastoma in an adult: First case in the world.

Primary central nervous system neuroblastoma (PCNS-NBL) is a rare and aggressive malignant tumour. Pleural metastases of PCNS-NBL have not been documented before. We report a case of a 30-year-old male patient, with a history of PCNS-NBL treated with surgery, radiation and chemotherapy. Three years later, he presented an aggravated dyspnoea with impaired general condition. The different investigations confirmed that his PCNS-NBL has relapsed with bone, lymph nodes and bilateral pleural metastases. Because of the disseminated disease and the poor general condition of the patient, only symptomatic treatment measures were preconized. The patient died 3 months later following cardiorespiratory arrest. To the best of our knowledge, this is the first case reporting bilateral pleural metastases of a PCNS-NBL in a young adult.

Miliary tuberculosis following intravesical Bacillus Calmette and Guérin therapy: A rare complication of a frequent procedure.

The standard treatment for superficial vesical tumors is transurethral resection (TUR) followed by intravesical instillation of Bacillus Calmette and Guérin (BCG). Pulmonary complications of BCG-therapy are rare but could be life threatening. We report the case of a 54-year-old patient who received BCG-therapy after TUR. After the sixth session of BCG instillations, the patient was diagnosed with a miliary tuberculosis secondary to BCG-therapy. We observed a progressive clinical and radiological improvement under specific tuberculosis treatment. Early diagnosis of pulmonary side effects of BCG-therapy and prompt treatment are the keys to complete recovery and survival.

Inflammatory myofibroblastic tumor of the lung: A rare entity.

Inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal tumor usually seen within the first and second decade. They are extremely rare in adults, constituting less than 1% of adult lung tumors. It's usually benign, but it had a tendency for local recurrence. We report a case of asymptomatic inflammatory myofibroblastic tumor of lung in a 46-year-old non-smoker woman.

[Predictive factors of recurrence in spontaneous pneumothorax]. / Facteurs prédictifs de récidive dans le pneumothorax spontané.

BACKGROUND: Spontaneous pneumothorax is usually a benign condition that most often affects young patients. Its most common complication is recurrence. This complication appears to be increased by some factors. AIM: To identify predictors of recurrence in spontaneous pneumothorax through a series of 204 cases. METHODS: A retrospective study of 204 cases of patients hospitalized for spontaneous pneumothorax. 50 patients experienced at least one recurrence. The study of predictors of recurrence is based on the X2 test for the univariate analysis and logistic regression for the multivariate analysis. RESULTS: The average age of our patients was 37 ± 7.6 years. A male predominance was noted (97.6 %). 80.4% of patients were smokers. Pneumothorax is considered primary in 65.2 % of cases. Fifty patients had at least one recurrence of their pneumothorax. Smoking and the pursuit of tobacco intoxication were the two risk factors for recurrence in our patients. Gender, age, side, importance of pneumothorax and therapeutic means of the first episode as well as the primary or secondary pneumothorax did not influence recurrence. In the multivariate analysis the pursuit of tobacco intoxication was the only predictor factor of recurrence. CONCLUSION: The recurrence is the most common complication of spontaneous pneumothorax. This risk appears to be increased by smoking and the pursuit of tobacco intoxication. Thus smoking cessation could be a simple and effective means to prevent recurrence.