RESUMEN
Francisella tularensis is the causative agent of tularemia. We tested the susceptibility of 278 F. tularensis isolates from the United States received during 2009-2018 to 8 antimicrobial drugs (ciprofloxacin, levofloxacin, doxycycline, tetracycline, gentamicin, streptomycin, chloramphenicol, and erythromycin). All isolates were susceptible to all tested drugs.
Asunto(s)
Francisella tularensis , Tularemia , Humanos , Estados Unidos/epidemiología , Pruebas de Sensibilidad Microbiana , Antibacterianos/farmacología , Antibacterianos/uso terapéutico , Tularemia/epidemiología , Tularemia/tratamiento farmacológico , Doxiciclina/farmacología , Doxiciclina/uso terapéuticoRESUMEN
This study reports on the validation of a real-time polymerase chain reaction test targeting the vomp region of Bartonella quintana. The assay displayed 100% sensitivity and specificity for the 52 bloods and 159 cultures tested. Molecular diagnosis of Bartonella quintana can aid clinical treatment during acute infection.
Asunto(s)
Bartonella henselae , Bartonella quintana , Humanos , Bartonella quintana/genética , Reacción en Cadena en Tiempo Real de la PolimerasaRESUMEN
Infection with Borrelia miyamotoi in California, USA, has been suggested by serologic studies. We diagnosed B. miyamotoi infection in an immunocompromised man in California. Diagnosis was aided by plasma microbial cell-free DNA sequencing. We conclude that the infection was acquired in California.