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1.
Soc Sci Res ; 79: 141-159, 2019 03.
Artículo en Inglés | MEDLINE | ID: mdl-30857659

RESUMEN

Recent work shows that national income distributions are converging, with stratified nations becoming more equal and egalitarian countries becoming more unequal. I replicate this finding using more recent data from multiple sources, drawing from 3006 observations across 152 countries from the Standardized World Income Inequality Database (SWIID) and 238 observations across 46 countries from the Luxembourg Income Study (LIS) during the 1990-2015 period. I find that a country's initial Gini is negatively related to subsequent change in the Gini (i.e., ß-convergence), with egalitarian and stratified countries both drifting towards a more moderate level of inequality. I then test several theoretical explanations for this trend, including (1) sectoral transitions, (2) economic development, (3) global diffusion, (4) public sentiment, and (5) statistical bias. Overall, the results are most consistent with the latter two accounts, indicating a public aversion to, and statistical bias against, extreme levels of (in)equality. By contrast, ß-convergence is not explained by sectoral transitions, nor do development or globalization appear to accelerate the process, casting doubt on alternative interpretations. Overall, the findings suggest that scholars should begin to account for convergence dynamics when modeling income distributions within nations.

2.
Sci Data ; 2: 150069, 2015 Nov 24.
Artículo en Inglés | MEDLINE | ID: mdl-26602009

RESUMEN

There is a demand for regularly updated, broad-scale, accurate land cover information in Victoria from multiple stakeholders. This paper documents the methods used to generate an annual dominant land cover (DLC) map for Victoria, Australia from 2009 to 2013. Vegetation phenology parameters derived from an annual time series of the Moderate Resolution Imaging Spectroradiometer Vegetation Indices 16-day 250 m (MOD13Q1) product were used to generate annual DLC maps, using a three-tiered hierarchical classification scheme. Classification accuracy at the broadest (primary) class level was over 91% for all years, while it ranged from 72 to 81% at the secondary class level. The most detailed class level (tertiary) had accuracy levels ranging from 61 to 68%. The approach used was able to accommodate variable climatic conditions, which had substantial impacts on vegetation growth patterns and agricultural production across the state between both regions and years. The production of an annual dataset with complete spatial coverage for Victoria provides a reliable base data set with an accuracy that is fit-for-purpose for many applications.


Asunto(s)
Agricultura , Imágenes Satelitales , Monitoreo del Ambiente , Victoria
3.
Sci Data ; 2: 150070, 2015 Nov 24.
Artículo en Inglés | MEDLINE | ID: mdl-26602150

RESUMEN

Land Use Information is a key dataset required to enable an understanding of the changing nature of our landscapes and the associated influences on natural resources and regional communities. The Victorian Land Use Information System (VLUIS) data product has been created within the State Government of Victoria to support land use assessments. The project began in 2007 using stakeholder engagement to establish product requirements such as format, classification, frequency and spatial resolution. Its genesis is significantly different to traditional methods, incorporating data from a range of jurisdictions to develop land use information designed for regular on-going creation and consistency. Covering the entire landmass of Victoria, the dataset separately describes land tenure, land use and land cover. These variables are co-registered to a common spatial base (cadastral parcels) across the state for the period 2006 to 2013; biennially for land tenure and land use, and annually for land cover. Data is produced as a spatial GIS feature class.


Asunto(s)
Recursos Naturales , Conservación de los Recursos Naturales , Victoria
4.
Soc Sci Res ; 53: 231-8, 2015 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-26188450

RESUMEN

A number of recent studies show that income inequality is declining between countries. In this research note, I question the significance of this trend by examining the role of initial conditions in producing convergence. An important (but neglected) property of inequality dynamics is the tendency for extreme distributions to become more moderate. When income disparities are large, the subsequent trend is biased toward convergence. Conversely, when initial conditions approach parity, divergence becomes the more likely long-term outcome. I apply this principle to trends in GDP PC across 127 countries during the 1980-2010 period. Using counterfactual analysis, I manipulate the initial level of inequality in GDP PC while holding constant each country's observed growth rate during the sample period. I find that the growth dynamics of GDP PC produce either convergence or divergence based simply on the initial distribution of income. The point of transition occurs at a moderate level of inequality, whether using population weights (Gini=.365) or not (Gini=.377). I conclude that the recent convergence observed in GDP PC is primarily a function of large income gaps between countries and would not have materialized at more moderate levels of initial inequality. By contrast, an examination of the pre-1950 period reveals divergent growth patterns that are not sensitive to initial conditions.


Asunto(s)
Países Desarrollados , Países en Desarrollo , Desarrollo Económico/tendencias , Producto Interno Bruto/tendencias , Renta/tendencias , Humanos , Factores Socioeconómicos
5.
Soc Sci Res ; 42(2): 401-17, 2013 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-23347484

RESUMEN

International development scholars advance contrasting theoretical explanations for the hypothesized link between trade and growth. Diffusion-based models suggest that trade with integrated partners provides states with greater access to technical knowledge. Structure-based models propose that trading with isolated partners produces a bargaining advantage. In this study, we adjudicate between these competing visions by applying Bonacich's (1987) measure of power centrality to the international trade network. We manipulate the procedure's "attenuation factor" (ß) such that a state's trade centrality can be enhanced when a state is connected to either central or isolated partners. Drawing from a sample of 101 states during the 1980-2000 period, we use difference-of-logs models to assess the impact of trade centrality on economic growth net of controls. We find that the positive relationship between trade centrality and growth peaks when states trade with isolated partners in the periphery.

6.
Hum Gene Ther ; 22(5): 595-604, 2011 May.
Artículo en Inglés | MEDLINE | ID: mdl-21410419

RESUMEN

To generate sufficient clinical-grade vector to support a phase I/II clinical trial of adeno-associated virus serotype 8 (AAV8)-mediated factor IX (FIX) gene transfer for hemophilia B, we have developed a large-scale, good manufacturing practice (GMP)-compatible method for vector production and purification. We used a 293T-based two-plasmid transient transfection system coupled with a three-column chromatography purification process to produce high-quality self-complementary AAV2/8 FIX clinical-grade vector. Two consecutive production campaigns using a total of 432 independent 10-stack culture chambers produced a total of ∼2 × 10(15) vector genomes (VG) by dot-blot hybridization. Benzonase-treated microfluidized lysates generated from pellets of transfected cells were purified by group separation on Sepharose beads followed by anion-exchange chromatography. The virus-containing fractions were further processed by gel filtration and ultrafiltration, using a 100-kDa membrane. The vector was formulated in phosphate-buffered saline plus 0.25% human serum albumin. Spectrophotometric analysis suggested ∼20% full particles, with only low quantities of nonviral proteins were visible on silver-stained sodium dodecyl sulfate-polyacrylamide gels. A sensitive assay for the detection of replication-competent AAV was developed, which did reveal trace quantities of such contaminants in the final product. Additional studies have confirmed the long-term stability of the vector at -80°C for at least 24 months and for at least 24 hr formulated in the clinical diluent and stored at room temperature within intravenous bags. This material has been approved for use in clinical trials in the United States and the United Kingdom.


Asunto(s)
Biotecnología/métodos , Dependovirus , Terapia Genética/métodos , Vectores Genéticos/genética , Hemofilia B/terapia , Línea Celular , Cromatografía en Gel , Cromatografía por Intercambio Iónico , Ensayos Clínicos como Asunto , Hemofilia B/genética , Humanos , Immunoblotting , Espectrofotometría
7.
Soc Sci Med ; 72(4): 617-24, 2011 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-21215504

RESUMEN

Recent studies characterize the last half of the twentieth century as an era of cross-national health convergence, with some attributing welfare gains in the developing world to economic growth. In this study, I examine the extent to which welfare outcomes have actually converged and the extent to which economic development is responsible for the observed trends. Drawing from estimates covering 195 nations during the 1955-2005 period, I find that life expectancy averages converged during this time, but that infant mortality rates continuously diverged. I develop a narrative that implicates economic development in these contrasting trends, suggesting that health outcomes follow a "welfare Kuznets curve." Among poor countries, economic development improves life expectancy more than it reduces infant mortality, whereas the situation is reversed among wealthier nations. In this way, development has contributed to both convergence in life expectancy and divergence in infant mortality. Drawing from 674 observations across 163 countries during the 1980-2005 period, I find that the positive effect of GDP PC on life expectancy attenuates at higher levels of development, while the negative effect of GDP PC on infant mortality grows stronger.


Asunto(s)
Salud Global , Disparidades en el Estado de Salud , Mortalidad Infantil/tendencias , Esperanza de Vida/tendencias , Desarrollo Económico , Humanos , Recién Nacido , Apoyo Social , Bienestar Social
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