Asunto(s)
Anaplasia/patología , ARN Helicasas DEAD-box/genética , Neoplasias Renales/patología , Mutación , Síndromes Neoplásicos Hereditarios/patología , Neuroblastoma/patología , Ribonucleasa III/genética , Sarcoma/patología , Anaplasia/complicaciones , Anaplasia/genética , Niño , Humanos , Neoplasias Renales/complicaciones , Neoplasias Renales/genética , Masculino , Síndromes Neoplásicos Hereditarios/complicaciones , Síndromes Neoplásicos Hereditarios/genética , Neuroblastoma/complicaciones , Neuroblastoma/genética , Pronóstico , Sarcoma/complicaciones , Sarcoma/genéticaRESUMEN
Infection-associated hemophagocytic syndrome is a rare, potentially fatal complication of systemic infection. It occurs most often in immunocompromised patients associated with a viral infection but the spectrum of conditions have been broadened to include virtually every type of infectious pathogen, malignancy and immunosuppressive therapy. We present three pediatric patients with a similar clinical history of pancytopenia, hepatosplenomegaly, and acute liver failure, and discuss the autopsy findings.
Asunto(s)
Infecciones/complicaciones , Linfohistiocitosis Hemofagocítica , Autopsia , Biopsia , Médula Ósea/patología , Enfermedad Crítica , Femenino , Humanos , Lactante , Linfohistiocitosis Hemofagocítica/diagnóstico , Linfohistiocitosis Hemofagocítica/etiología , Linfohistiocitosis Hemofagocítica/mortalidad , Linfohistiocitosis Hemofagocítica/patología , Masculino , Bazo/patología , Síndrome , Factores de TiempoRESUMEN
This is the case of an 11-year-old girl who presented with a right adnexal mass and vague abdominal symptoms since seven months prior to her hospital admission for surgery. CT-scan and sonographic images were those of a benign lesion, probably ovarian torsion or infarction. Serum tumoral markers were normal. A right salpingo-oophorectomy and appendectomy were performed. Pathology examination revealed a cavernous hemangioma of the ovary. The clinicopathologic presentation of this unusual benign ovarian tumor is discussed.
