Giant adrenal myelolipoma.

Authors present a case of giant adrenal myelolipoma, where the tumor was hormonally inactive but caused abdominal and flank pain. The huge tumor, a 20x18x10 cm mass, was surgically removed. The ipsilateral kidney was preserved.

[Urinary bladder and paraurethral endometriosis]. / A húgyhólyagi és a paraurethralis endometriosisról.

Authors report a case of bladder and a case of paraurethral endometriosis. The mode of sanitation was by means of TUR and surgery, respectively. Based on the available literary data, the assumptions related to development of the disease; its pathology, symptoms and treatment are discussed in brief. Despite the frequency of the disorder, exact diagnosis might take months, perhaps even years. Due to the difficulties in diagnosing this disease, correct diagnosis can be expected from biopsy, as in our case.

[Eosinophil cystitis]. / Eosinophil cystitis.

Authors report on two rare cases of eosinophilic cystitis, giving a review of the etiologic assumptions and pathogenetic, pathologic aspects of the disease, based on the available literary data. The course of the disease can be either acute or subacute, and is most often chronic. Relapse and progression can interchange in irregular manner, attention is therefore called to the importance of follow-ups. Resection deep into the intact--also containing muscle fibre--as well as histologic examination are considered essential as the only method of differentiation, giving precise diagnosis in the present two cases, too.

[Schistosomiasis of the bladder]. / A húgyhólyag schistosomiasisa.

Authors review a case of urinary schistosomiasis, where the process caused left sided urinary obstruction. Because of the suspicion of a tumor transurethral resections was performed, where after the ureter passage became unhindered. Diagnosis became clear upon the histological examination of the resected tissue. Based on the cited literature, reference is made to the mortality rate of the disease in the expanded endemic areas, as well as to the high number of patients at risk. A brief summery is given of the pathology, symptoms, diagnostics of the disease, with mention of differentiation and therapeutic possibilities as well. With regard to importation of the disease, attention is called to the importance of careful anamnesis.

[Retroperitoneal malignant fibrous histiocytoma]. / Retroperitonealis malignus fibrosus histiocytoma.

Authors review the case history and follow-up of a rare malignant fibrous histiocytoma patient, based on the relevant literary data. The tumor filled the retroperitoneum on the right side, in front of the right kidney. Intravenous urography and computer tomography revealed a 10 x 15 cm sized mass, suspect of being a kidney tumor. Upon surgery, the tumor was found to be a retroperitoneal malignant fibrous histiocytoma. In connection to the case, a brief review is given of the storiform type of malignant fibrous histiocytoma, regarding its etiological, clinical and pathological aspects, the difficulties in diagnosis, as well as the therapeutic possibilities. Authors regard their case worthy of publication because of the retroperitoneal location and significant size of the tumor, and because of the unproven diagnosis prior to surgery. Even after 4 years the patient is symptom- and complaint-free, and CT has revealed no metastases.

A case of a calcified renal cyst.

Authors review a case of a calcified renal cyst. The literary data at hand give evidence that the spreading processes in the kidney can be benign or malignant according to their form of calcification and their localisation. Despite the modern diagnostic techniques, it is not easy to set up the diagnosis or to avoid the need for surgery, as was the case in the present report.

Eosinophilic cystitis.

Authors report on two rare cases of eosinophilic cystitis, giving a review of the etiologic assumptions and pathogenetic, pathologic aspects of the disease, based on the available literary data. The course of the disease can be either acute or subacute, and is most often chronic. Relapse and progression can interchange in irregular manner, attention is therefore called to the importance of follow-ups. Resection deep into the intact--also containing muscle fibre--as well as histologic examination are considered essential as the only method of differentiation, giving precise diagnosis in the present two cases, too.

Retroperitoneal malignant fibrous histiocytoma.

Authors review the case history and follow-up of a rare malignant fibrous histiocytoma patient, based on the relevant literary data. The tumour filled the retroperitoneum on the right side, in front of the right kidney. Intravenous urography and computer tomography revealed a 10 x 15 cm sized mass, suspect of being a kidney tumour. Upon surgery, the tumour was found to be a retroperitoneal malignant fibrous histiocytoma. In connection with the case, a brief review is given of the storiform type of malignant fibrous histiocytoma, regarding its aetiological, clinical and pathological aspects, the difficulties in diagnosis, as well as the therapeutic possibilities. Authors regard their case worthy of publication because of the retroperitoneal location and significant size of the tumour, and because of the unproven diagnosis prior to surgery. Even after 4 years the patient is symptom- and complaint-free, and CT has revealed no metastases.

[Renal oncocytoma]. / Vese oncocytoma.

Authors review the case history of three patients with kidney tumours which had been surgically removed. In two of the cases radical nephrectomy while in one, organ-preserving surgery was performed. In all three cases histology revealed benign kidney tumours-oncocytomas. In light of the available literature authors indicate that preoperative diagnosis is almost impossible. Furthermore, it is their opinion that this benign kidney tumour has a less frequent occurrence than earlier thought.

Spontaneous (renal) pelvic rupture. Two cases cured by conservative therapy.

Two cases of spontaneous pelvic rupture are presented. In Case 1 (female, 49 years) and Case 2 (male, 63 years) the rupture was due to obstruction and tumorous compression of the ureter, respectively. Authors deal with the diagnostic difficulties and the possibility of a cure without open surgery. Conservative therapy (double-J ureteral catheter and pigtail catheter) was successful in both cases. The pertinent literature is briefly reviewed.

Prostatic leiomyosarcoma. / A prostata leiomyosarcomája.

The histopathological findings from the third prostate operation of a 63-year-old patient proved that his leiomysarcoma was malignant. Leiomyosarcoma is a disease of low incidence. Of 1000 cases of a carcinoma of prostate one proves to be this disease. Its clinical distinction from benign prostate disease meets difficulties. A survey of literature has shown that even multiple aggressive therapy fails when the process has overpassed the limits of the organ. Early diagnosis followed be radical pre- and postoperative X-irradiation may lead to long-term survival. Neither cytostatic nor hormonal therapy is successful. The course of the illness of our patients merits interest because of the rarity of the disease and the diagnostic difficulties.

Experiences of 25 orthotopic ileal neobladders.

Authors report on their results obtained from orthotopic ileal neobladders following 25 cases of radical cystectomy. Analysis is given of the possible complications, their prevention, as well as of surgical techniques. It is determined that orthotopic ileal neobladder is one of the best bladder substitution methods, giving the patient a chance for a high quality of life.

Experiences on 25 cases of radical cystectomy.

Authors review their early experiences and the oncopathological relations in respect to 25 cases of radical cystectomy involving orthotopic bladder substitution. The difficulties of diagnostics and indication are discussed. Attention is drawn to the fact that pathological "staging", "grading" are not entirely exact and reliable, though surgical indication is positioned on these. It is the opinion of authors that in case of TIG3 radical surgery is indicated. Due to the shortness of the follow-up periods, no studies on survival were performed. It remains an open question whether radical cystectomy is indicated as opposed to the possible choice of organ-preserving surgery.

Schistosomiasis of the urinary bladder.

Authors review a case of urinary schistosomiasis, where the process caused left-sided urinary obstruction. Because of the suspicion of a tumor transurethral resection was performed, whereafter the ureter passage became unhindered. Diagnosis became clear upon the histological examination of the resected tissue. Based on the cited literature, reference is made to the mortality rate of the disease in the expanded endemic areas, as well as to the high number of patients at risk. A brief summary is given of the pathology, symptoms, diagnostics of the disease, with mention of differentiation and therapeutic possibilities as well. With regard to importation of the disease, attention is called to the importance of careful anamnesis.

Retroperitoneal malignant fibrous histiocytoma.

Authors review the case history and follow-up a rare malignant fibrous histiocytoma patient, based on the relevant literary data. The tumor filled the retroperitoneum on the right side, in front of the right kidney. Intravenous urography and computer tomography revealed a 10 x 15 cm sized mass, suspect of being a kidney tumor. Upon surgery, the tumor was found to be a retroperitoneal malignant fibrous histiocytoma. In connection to the case, a brief review is given of the storiform type of malignant fibrous histiocytoma, regarding its etiological, clinical and pathological aspects, the difficulties in diagnosis, as well as the therapeutic possibilities. Authors regard their case worthy of publication because of the retroperitoneal location and significant size of the tumor, and because of the unproven diagnosis prior to surgery. Even after 4 years the patient is symptom- and complaint-free, and CT has revealed no metastases.

Studies on tumourous and other urogenital patients with respect to antigens of oncogenic adenovirus.

The possible connection of viruses with tumours was investigated by serologic examinations. Concerning the presence of antibodies against adenoviruses, especially those against the early non-virion antigens of oncogenic adenovirus type 12, approximately 4000 tests were made with sera of 446 urogenital patients with and without tumours and 70 ones with internal diseases. It was found by complement fixation tests that antibodies against nonvirion antigens of adenoviruses were present in 53% of urogenital patients suffering from malignant tumours and prostatic hypertrophy, in 18% of non-tumourous urological patients and in 4% of patients with internal diseases, respectively. The results suggest that adenoviruses may play a role in tumourous diseases of the urogenital organs.

Ureter and bladder replacement following radical cystectomy.

During the course of Hautmann-type bladder replacement, left sided ureter damage necessitated ureter replacement as well, modifying the removal of the ileum-bladder. The proximal 20 cm length of the 70 cm long isolated ileum portion was not detubularized; instead it was slipped through the mesosigma and mesocolon to the left side of the colon and the left ureter stub was anastomized without tautness to the ileum according to Le Duc. The implantation of the right ureter was accomplished according to Hautmann. For similar cases authors recomment this procedure, since neither stricture, nor reflux could be detected at later examinations.

Organ-preserving surgery of renal cell carcinoma: report of four cases.

Authors removed the renal tumour of four patients by means of resection in an organ-preserving manner. Of the four patients, one had bilateral carcinoma. The right-sided carcinoma of this patient was removed by resection while the other kidney was removed radically, by transabdominal approach. In three of the four cases which were in the process of stages T1 and N0M0, organ-preserving surgery was performed in the presence of intact opposite kidneys. Authors point out the fact that the resection method might be indicated even in the case of early (T1) stage tumours with intact opposite side kidneys. Furthermore, they do not recommend the enucleation of renal carcinomas for the surgical treatment of kidney tumours, since experimental studies have proved that these tumours can be transferred into the parenchyma of the kidney through the pseudocapsule of the tumour.

Bilateral ureteric replacement with ileum.

In connection with a report of a case, authors discuss in outline the possibilities of ureter replacement. If both the ureters are injured, they can be substituted with one single segment of the intestine, as it happened in their case. Authors raise the idea that a longer segment of the intestine used for substitution provides sufficient capacity and isoperistaltic function, and this may protect from the negative effects of possible vesicoileal reflux. In this case, the reflux does not spread to the kidneys even if the ureteroileal was not made with anti-reflux technique.

Kidney oncocytoma.

Authors review the case history of three patients with kidney tumours which had been surgically removed. In two of the cases radical nephrectomy while in one, organ-preserving surgery was performed. In all the cases histology revealed benign kidney tumours--oncocytomas. In light of the available literature authors indicate that preoperative diagnosis is almost impossible. Furthermore, it is their opinion that this benign kidney tumour has a less frequent occurrence than earlier thought.