RESUMEN
The genetic diversity of enteric viruses co-circulating in a cohort of patients with viral gastroenteritis in a large tertiary paediatric hospital in London, UK, was determined. Multiple strains of noroviruses (NV), sapoviruses (SV) and astroviruses (HAsV) were detected in these patients, indicating the likelihood of multiple introductions from different sources, possible sub-clinical infections and simultaneous infection with different viruses in immunocompromised and other patients. Routine screening of immunocompromised patients and infection control procedures are important to prevent nosocomial infection.
Asunto(s)
Infecciones por Astroviridae/virología , Infecciones por Caliciviridae/virología , Gastroenteritis/virología , Mamastrovirus/genética , Norovirus/genética , Sapovirus/genética , Adolescente , Infecciones por Astroviridae/epidemiología , Infecciones por Caliciviridae/epidemiología , Niño , Preescolar , Análisis por Conglomerados , Infección Hospitalaria/epidemiología , Infección Hospitalaria/virología , Heces/virología , Hospitales Pediátricos , Humanos , Lactante , Londres , Mamastrovirus/aislamiento & purificación , Norovirus/aislamiento & purificación , Filogenia , ARN Viral/genética , ARN Viral/aislamiento & purificación , Reacción en Cadena de la Polimerasa de Transcriptasa Inversa , Sapovirus/aislamiento & purificación , Análisis de Secuencia de ADN , Homología de SecuenciaRESUMEN
All couples attending the premarital examination at four selected sites in Zhejiang and Yunnan provinces in China were included in this study. Blood from 9952 individuals was tested for HIV-1 using a gelatin particle agglutination technique. There were no HIV-positive individuals in Zhejiang. In Yunnan, 28 of 3742 individuals were positive, a prevalence of 0.75%. The premarital examination should be used for voluntary counselling and testing and anonymous surveillance for HIV in high prevalence areas.
