RESUMEN
Ancient DNA shows continuity between living and ancient Maya communities.
Asunto(s)
Conducta Ceremonial , Civilización , ADN Antiguo , Gemelos , Femenino , Humanos , Masculino , Historia Antigua , Gemelos/historia , Niño , Civilización/historiaRESUMEN
Complex tools from 300,000-year-old deposit at Schöningen in Germany point to a "wood age".
Asunto(s)
Hombre de Neandertal , Madera , Animales , Arqueología , Alemania , Hombre de Neandertal/psicologíaRESUMEN
Moderns made mysterious ice age artifacts-implying overlap with Neanderthals.
Asunto(s)
Hombre de Neandertal , Animales , Humanos , Europa (Continente) , FósilesRESUMEN
Among Europeans, risk of multiple sclerosis rises with genes from Bronze Age Yamnaya herders.
Asunto(s)
ADN Antiguo , Esclerosis Múltiple , Humanos , Europa (Continente)/epidemiología , Genoma Humano , Esclerosis Múltiple/epidemiología , Esclerosis Múltiple/genética , Esclerosis Múltiple/historiaRESUMEN
8000 years ago-long before farming arrived-people in Siberia built defensive structures.
Asunto(s)
Caza , Humanos , Granjas/historia , Siberia , Caza/historiaRESUMEN
Giant family trees based on ancient DNA from thousands of people are revealing prehistoric politics and social structure.
RESUMEN
Despite more than 80 years of use in a number of conditions, including in critically ill patients, comments have recently arisen regarding the safety and efficacy of human serum albumin (HSA) as a therapeutic product and stabilizer/excipient in botulinum neurotoxins. This review summarizes the literature on the safety of HSA. Beyond decades of safe use, the largest clinical dataset of HSA safety is a large meta-analysis of HSA supplier data, which found only an extremely remote risk of serious adverse events across millions of doses of therapeutic concentrations of HSA. There is a paucity of literature identifying HSA-specific adverse events when used as a stabilizer/excipient; however, studies of HSA-containing botulinum neurotoxins (BoNTs) suggest that adverse events are not related to HSA. Polysorbates, which are synthetically produced and not physiologically inert, are contained in pending or new-to-market BoNT formulations. In contrast to HSA, evidence exists to suggest that polysorbates (particularly PS20/PS80) can cause serious adverse events (e.g., hypersensitivity, anaphylaxis, and immunogenicity).
Asunto(s)
Toxinas Botulínicas Tipo A , Toxinas Botulínicas , Humanos , Toxinas Botulínicas/efectos adversos , Albúmina Sérica Humana/efectos adversos , Excipientes , Polisorbatos , Toxinas Botulínicas Tipo A/efectos adversosRESUMEN
DNA from enslaved Black workers at a 19th century iron forge links them to living descendants. But the research swirls with ethical questions.
RESUMEN
After the Spanish conquest, horses transformed Native American tribes much earlier than historians thought.
Asunto(s)
Indio Americano o Nativo de Alaska , Caballos , Interacción Humano-Animal , Animales , América del Norte , España , Arqueología , HumanosRESUMEN
Ancient DNA reflects foreign influx to Swahili coast, but its culture is largely local.
RESUMEN
Genes reveal striking diversity within similar ice age cultures.
Asunto(s)
Diversidad Cultural , ADN Antiguo , Europa (Continente) , HumanosRESUMEN
Analysis reveals the chemicals applied to corpses in a 2700-year-old mummification workshop.
Asunto(s)
Momias , Humanos , Cadáver , Egipto , Historia Antigua , Momias/historiaRESUMEN
Meat from the butchered beasts would have fed hundreds.
Asunto(s)
Conducta Alimentaria , Procesos de Grupo , Caza , Carne , Hombre de Neandertal , Animales , Ingestión de Alimentos , Carne/historia , Hombre de Neandertal/psicología , Caza/historia , ElefantesRESUMEN
DNA from a medieval German cemetery opens a window on the history of today's largest Jewish population.
Asunto(s)
Judíos , Judíos/genética , Población/genética , Alemania , Cementerios/historia , ADN Antiguo , HumanosRESUMEN
By sequencing ancient hominins' DNA, Pääbo explored "what makes us uniquely human".
Asunto(s)
ADN Antiguo , Hominidae , Animales , Hominidae/genética , Humanos , Premio NobelRESUMEN
Genetic study of burials suggests whole families migrated to the island in the first millennium C.E.
Asunto(s)
Emigración e Inmigración , Población Blanca , Entierro , ADN Antiguo , Emigración e Inmigración/historia , Inglaterra , Historia Antigua , Humanos , Análisis de Secuencia de ADN , Población Blanca/genéticaRESUMEN
Studies seek clues to origins of farming, early languages.
Asunto(s)
Civilización , ADN Antiguo , Granjas , Lenguaje , Civilización/historia , Granjas/historia , Historia Antigua , Humanos , Lenguaje/historia , Medio OrienteRESUMEN
Researchers hide ancient weapons and bat skulls, upload data as bombs fall.
RESUMEN
Russian disinformation campaign targets routine research on bat parasites.