1.
Spectrochim Acta A Mol Biomol Spectrosc
; 69(3): 849-52, 2008 Mar.
Artículo
en Inglés
| MEDLINE
| ID: mdl-17604217
RESUMEN
A new simple, economical, rapid, precise and accurate method for simultaneous determination of rabeprazole sodium and itopride hydrochloride in capsule dosage form has been developed. The method is based on ratio spectra derivative spectrophotometry. The amplitudes in the first derivative of the corresponding ratio spectra at 231nm (minima) and 260nm were selected to determine rabeprazole sodium and itopride hydrochloride, respectively. The method was validated with respect to linearity, precision and accuracy.