[Parallel pharmacological correction of myocardial dysfunction, cognitive and psychopathological disordres in patients with congestive heart failure].

Was examined 92 patients with congestive heart failure III-IV FC with fraction of emission left ventricle < 45% against coronary artery disease. Patients of control group received basic therapy (according to recommendations of the Ukrainian society of cardiology), the 1 group--in addition received a preparation of Vazonat within 15 days intravenously in a dose of 1000 mg a day further are out-patient within 1 month on 250 mg 3 times per os; the 2 group--under the same scheme a preparation of Vazonat and a day tranquilizer of Adapto in a dose of 500 mg twice a day throughout all term of supervision. It is established that addition of Vazonat to basic treatment leads to additional effect concerning improvement of indicators cardio-hemodynamic, to improvement congestive functions. Joint appointment of preparations of Vazonat and Adaptol against basic treatment leads to more expressed improvement congestive functions, to progressive reduction of degree of trouble, depression.

[The prognostic significance of the blood flow volume of the abdominal cavity in peptic ulcer patients]. / Prognosticheskoe znachenie velichiny krovotoka briushnoi polosti u bol'nykh iazvennoi bolezn'iu.

A total of 25 patients with duodenal ulcer were examined. Central bloodflow, that of the abdominal cavity, and characteristics of the vegetative tone were studied by the variation pulsometry method. Disturbances were revealed in the hemodynamics, manifested by a drop in cardiac output (CO) and increase in the blood volume which were particularly pronounced in unfavourable course of the disease. It has been established that the abdominal cavity CO above 1.55 l/min suggests a favourable course of the disease, while its lower values are thought to be associated with unfavourable one. The influence of the vegetative nervous system on the abdominal cavity hemodynamics is not unidirectional.

[The effect of bile secretion on duodenal motility and intracavitary pressure]. / Vliianie sekretsii zhelchi na motoriku i vnutripolostnoe davlenie dvenadtsatiperstnoi kishki.

Open catheters were used to study the interdigestive motoric of the duodenum in 80 patients with chronic noncalculous cholecystitis and 30 patients with postcholecystectomy syndrome. Most frequently the patients showed hypomotor dyskinesias of duodenum (stages I-II) with an increase or decrease of the intracavitary pressure. Liobil produced a stimulating effect on the duodenal motor function. Patients with chronic noncalculous cholecystitis showed a clear increase of the amplitude of intestinal contractions. Patients with postcholecystectomy syndrome revealed after liobil administration an increase of the III phase time. In 9 patients formerly absent spontaneous rhythmic phase appeared.

[A comparative assessment of gastric secretory function using a probe method and intragastric Ph-metry]. / Sravnitel'naia otsenka sekretornoi funktsii zheludka, izuchaemoi zondovym metodom i intragastral'noi Ph-metriei.

To compare informative value of probing and intragastric pH-metry, relevant examination was performed in 130 patients with chronic gastritis, 132 patients with noncomplicated peptic ulcer and 50 healthy subjects. pH values obtained with probing and intragastric pH-metry did not differ significantly in defects of gastric mucosa, superficial gastritis, peptic ulcer. In apparent atrophic gastritis intragastric pH-metry detected minimal secretion of H ions in all the patients, whereas probing failed to show it. Intragastric pH-metry is useful in recognizing duodenogastric reflux and decompensated acid stomach as shown by antral basal pH (below 2.0).

[The effect of food intake, atropine and No-spa on autonomic tonus and hemodynamic indices in patients with peptic ulcer]. / Vliianie priema pishchi, atropina i no-shpy na vegetativnyi tonus i pokazateli gemodinamiki u bol'nykh iazvennoi bolezn'iu.

A study of 40 patients with duodenal ulcer by means of methods of variational pulsimetry and tetrapolar rheography revealed noncoordination of the regulation of the central and regional hemodynamics after intake of food. Atropin produced an inhibitory effect on the central hemodynamics, reduction of blood volume in the abdominal cavity after No-spa intake.

[Immunoreactive insulin, C-peptide and insulin-containing erythrocytes in chronic pancreatitis]. / Immunoreaktivnyi insulin, C-peptid i insulinsoderzhashchie éritrotsity pri khronicheskom pankreatite.

The levels of immunoreactive insulin, C-peptide and insulin containing erythrocytes were studied in 26 patients on the 2nd and 12th day of their stay in hospital. A higher level of C-peptides was found in the patients as compared to healthy subjects. The level of immunoreactive insulin of the patients did not differ significantly from that of healthy subjects. The number of insulin containing erythrocytes in the patients was much lower than in healthy subjects. Their number after therapy did not rise considerably. There was no correlation between these indices.

[Methodologic problems and practical aspects of training gastroenterologists at a specialized department of the Institute of Postgraduate Education of Physicians]. / Metodicheskie problemy i voprosy prakticheskogo obucheniia vracha-gastroenterologa na spetsializirovannoi kafedre Instituta usovershenstvovaniia vrachei.

The training of gastroenterologists at the respective specialized department of the Institute for Postgraduate Medical Training should first identify individual shortcomings of postgraduate experience and use them as the basis for further studies employing a variety of forms and methods, with independent clinical work, daily analysis of cases and the mastering of new diagnostic and therapeutic procedures being prominent among those. Experience shows that therapeutists, with at least 5 years of field work behind them, make the best gastroenterologic specialists.