RESUMEN
OBJECTIVE: Endometrial cancer (EC) is a rare condition in young women. The objective of this study was to evaluate the risk of pelvic lymph node (LN) metastasis in young women with EC who are candidates for conservative management. METHODS: Using the SEER database, a population-based analysis was conducted to identify women <45 years with grade 1, 2, or 3 endometrioid adenocarcinoma stage IA (FIGO 2009) who underwent pelvic lymphadenectomy with at least ten LNs removed. The LN macrometastases rate based on conventional histological diagnosis was analyzed according to tumor grade and myometrial invasion (MI) on final histology. RESULTS: A cohort of 1284 women was analyzed. The LN metastasis rates were: 2/414 (0.5%) grade 1 EC without MI, 5/239 (2.1%) grade 2 or 3 EC without MI, 5/308 (1.6%) grade 1 EC with MI, and 14/323 (4.3%) grade 2 or 3 EC with MI. Tumor size was not correlated with LN metastasis probability. CONCLUSIONS: Young patients eligible for conservative management have a low rate of LN macrometastasis, especially in stage IA without MI grade 1 EC. A systematic lymphadenectomy should not be performed in these patients. Prospective study evaluating the sentinel LN mapping in conservative management of EC could be performed to assess the LN micrometastasis rate.
Asunto(s)
Carcinoma Endometrioide/patología , Neoplasias Endometriales/patología , Ganglios Linfáticos/patología , Adolescente , Adulto , Factores de Edad , Carcinoma Endometrioide/epidemiología , Carcinoma Endometrioide/cirugía , Estudios de Cohortes , Neoplasias Endometriales/epidemiología , Neoplasias Endometriales/cirugía , Femenino , Preservación de la Fertilidad , Humanos , Escisión del Ganglio Linfático , Ganglios Linfáticos/cirugía , Metástasis Linfática , Clasificación del Tumor , Estadificación de Neoplasias , Estudios Retrospectivos , Programa de VERF , Estados Unidos/epidemiología , Adulto JovenRESUMEN
AIM: To describe the prenatal features and management of a congenital intra hepatic fistula. MATERIAL AND METHODS: Case report Results: Congenital intra hepatic fistula are extremely rare. The prenatal ultrasound seiology is described. CONCLUSION: Prenatal diagnosis of these anomalies may improve pre and post natal management.