RESUMEN
Bacterial urinary tract infections (UTI) commonly occur in children; if left untreated, they may result in severe consequences such as uro-sepsis and renal damage. This study aimed to determine the bacterial profile, antimicrobial susceptibility patterns and associated factors among paediatric patients suspected of urinary tract infections in Arba Minch General Hospital (AMGH). An institution-based cross-sectional study was conducted from 01 October 2020 to 31 January 2021. A convenient sampling technique was used to recruit the participants; data were collected using a pre-tested questionnaire. To quantify the bacteria (as per the Kass count, >105CFU/ml), midstream urine samples were streaked onto bacteriological media. Isolates were identified by following standard procedures. The antibiotic susceptibility test was performed as per the Kirby-Bauer disc diffusion technique. Data were analyzed using SPSS software. Out of the 246 children included, 38 (15.4%) were found to be positive for significant bacteriuria. Isolates of Escherichia coli, 9/38 (23.7%), and Staphylococcus aureus, 9/38 (23.7%), were the most predominant. The majority of Gram-negative bacterial (GNB) isolates showed resistance towards amoxicillin-clavulanate (89.5%), ampicillin (84.6%), and ceftazidime (81%). Likewise, 76.9 and 76.5% of Gram-positive bacteria (GPB), respectively, had shown resistance towards co-trimoxazole and tetracycline. Multi-drug and extensively drug resistance were detected respectively in the case of 68.4 and 15.8% of the total isolates; ESBL production was found in 57.1% of GNB, whereas 55.6% of S. aureus were methicillin-resistant S. aureus (MRSA). The process of un-circumcision was significantly associated with UTI [(adjusted odds ratio= 3.578; 95% confidence interval: 1.263 - 10.13; p=0.016)].
RESUMEN
Introduction: Ethiopians work very hard to control and eradicate the vector and the parasite of Onchocerciasis. However, some hard-to-reach areas are not adequately covered by interventions that have previously taken place in various endemic sites in the country. This study aimed to assess knowledge, attitude, and preventive practice of Onchocerciasis among Selamogo residents to enhance the expansion of interventions. Methods: We used a survey questionnaire to capture the data on 572 Selamago residents. We checked, cleaned, entered the data into EPI Info v.7, and analyzed it in STATA v.15. We fitted a binary logistic regression model to examine the associated factors. Variables significant at P < 0.20 were included in the model. We declared association at P < 0.05. Results: Of the 578 residents we approached, 572 (99%) responded to the interview. We found 48.30% of poor knowledge, 90.90% of poor attitude, and 85.70% preventive practice related to Onchocerciasis. Factors like Amhara ethnicity (AOR = 2.35, 95% CI: 1.05, 5.27), Orthodox Christianity (AOR = 1.87, 95% CI: 1.12, 3.10), Muslims (AOR = 2.28, 95% CI: 1.05, 4.94), secondary school (AOR = 2.31, 95% CI: 1.50, 3.55), diploma (AOR = 10.34, 95% CI: 4.62, 23.16), and preventability of Onchocerciasis (AOR = 3.02, 95% CI: 1.39, 6.55) were associated with KAP. Other factors like medical treatability, admission history to the health facilities, sex, and the number of households were also associated. Conclusion: The KAP related to Onchocerciasis is very poor compared to the indicators and evidence in the country. An intervention that considers local resources like taking the experience of groups with good knowledge, attitude, and preventive practice led by educated plus positive attitude people regarding the preventability and treatability of Onchocerciasis might be mandatory to improve the status.
