Asunto(s)
Antirreumáticos/efectos adversos , Colitis Ulcerosa/complicaciones , Infliximab/efectos adversos , Síndrome Metabólico/complicaciones , Infecciones por Mycobacterium no Tuberculosas/etiología , Mycobacterium marinum/aislamiento & purificación , Infecciones Oportunistas/etiología , Enfermedades Cutáneas Bacterianas/etiología , Alcoholismo/complicaciones , Antirreumáticos/uso terapéutico , Antituberculosos/uso terapéutico , Colitis Ulcerosa/tratamiento farmacológico , Diabetes Mellitus Tipo 2/complicaciones , Susceptibilidad a Enfermedades , Humanos , Infliximab/uso terapéutico , Masculino , Persona de Mediana Edad , Infecciones por Mycobacterium no Tuberculosas/tratamiento farmacológico , Infecciones por Mycobacterium no Tuberculosas/microbiología , Obesidad/complicaciones , Infecciones Oportunistas/tratamiento farmacológico , Infecciones Oportunistas/microbiología , Enfermedades Cutáneas Bacterianas/tratamiento farmacológico , Enfermedades Cutáneas Bacterianas/microbiologíaAsunto(s)
Fístula Pancreática/complicaciones , Pancreatitis Crónica/complicaciones , Enfermedades Pleurales/complicaciones , Derrame Pleural/etiología , Fístula del Sistema Respiratorio/complicaciones , Enfermedades Asintomáticas , Calcinosis/diagnóstico por imagen , Calcinosis/etiología , Colangiopancreatografia Retrógrada Endoscópica , Pancreatocolangiografía por Resonancia Magnética , Constricción Patológica , Humanos , Masculino , Persona de Mediana Edad , Conductos Pancreáticos/patología , Conductos Pancreáticos/cirugía , Seudoquiste Pancreático/etiología , Pancreatitis Crónica/diagnóstico por imagen , Derrame Pleural/diagnóstico por imagen , Stents , Tomografía Computarizada por Rayos XRESUMEN
Polycystic liver disease (PLD) is a hereditary disease inherited by autosomal dominant trait that occurs as a frequent extrarenal manifestation of autosomal dominant polycystic kidney disease (ADPKD). We report a case of a 59-year-old woman diagnosed with ADPKD associated with PLD. End-stage chronic renal failure with a secondary Budd-Chiari syndrome developed during the patient's clinical course. She underwent combined liver and kidney transplantation, with a successful response over a 9-year follow-up period.
RESUMEN
Inflammatory pseudotumor (IPT) of the liver is a rare benign tumor of unknown origin, it has the appearance of a malignant tumor but has a benign histology and clinical course. We report a case of a 63-year-old man diagnosed of IPT of the liver and followed for 10 years. During the clinical course, he developed a secondary Budd-Chiari syndrome, with a successful response to a transjugular intrahepatic portosystemic shunt over a 5-year follow-up period.
Asunto(s)
Síndrome de Budd-Chiari/etiología , Granuloma de Células Plasmáticas/complicaciones , Hepatopatías/complicaciones , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Factores de TiempoRESUMEN
Primary sclerosing cholangitis is an infrequent extraintestinal manifestation of ulcerative colitis. Damage to bile ducts is irreversible and medical therapies to prevent progression of the disease are usually ineffective. We describe a patient with long-standing ulcerative colitis, which was refractory to corticosteroid therapy who developed primary sclerosing cholangitis (biochemical stage II/IV) in the course of his pancolitis. Treatment with infliximab (5 mg/kg as an induction dose followed by maintenance doses every two months) was indicated because of steroid-dependent disease associated to primary sclerosing cholangitis as well as sacroiliitis and uveitis and previous episode of severe azathioprine-related hepatic toxicity. At present, after two years of follow-up, the patient is asymptomatic with normal liver tests and complete resumption of daily life activities. This case draws attention to the usefulness of anti-tumor necrosis factor-alpha therapy for the management of primary sclerosing cholangitis as extraintestinal manifestation of inflammatory bowel disease.
Asunto(s)
Anticuerpos Monoclonales/uso terapéutico , Colangitis Esclerosante/tratamiento farmacológico , Colitis Ulcerosa/tratamiento farmacológico , Resistencia a Medicamentos , Inmunosupresores/uso terapéutico , Esteroides/uso terapéutico , Anciano , Colangitis Esclerosante/diagnóstico , Colangitis Esclerosante/etiología , Colitis Ulcerosa/complicaciones , Colitis Ulcerosa/diagnóstico , Humanos , Infliximab , Masculino , Resultado del TratamientoRESUMEN
Ulcerative colitis is a chronic inflammatory bowel disease of unknown etiopathogenesis and increasing incidence in recent years. Perianal complications of ulcerative colitis are rare and seem to be associated with higher extent of inflammation and a more severe course of the disease. The cases of two male patients with severe corticoid-dependent ulcerative colitis of protracted clinical course who developed perianal fistulas and abscesses successfully treated with infliximab are reported. Treatment with infliximab was followed by perianal fistula closure with marked improvement in the quality of life over 2-year follow-up period.