An analysis of demographic, socio-economic and clinical variables for mental illness and mental illness relapse in south-east nigeria.

Mental health has come into the front burner of development challenges amid declining socio-economic outcomes, especially in developing countries. Insecurity, conflicts and extremely threatening events, which trigger mental disorders, are common in South-East Nigeria, with many military operations, unknown gunmen attacks and kidnapping leading to the cold-blood assassination and kidnap of dear ones. The study aimed to analyze the demographic, socio-economic and clinical variables for mental illness in South-East Nigeria. Consecutive sampling technique was used to obtain a three-year records of the cases of 380 index and 180 post-index points data of mental illness cases that met the inclusion criteria in a purposively selected public mental health hospital. Data were analyzed using both descriptive and inferential statistics, including frequency count, percentages, chi-square and multinomial logistic regression. Results showed that over a half (55.0%) of the patients were males, and 65.27% had post-primary education. The mean age of patients was 39.87 years. Slightly above half of the cases (55.26%) were single and 56.84% were unemployed. Schizophrenia (68.42%) topped the list of the cases. The rate of relapse was 52.1%, with males being in the majority (61.62%). About 61.62% of those who relapsed were unemployed, 9.60% were into business/trading, and 5.05% were professionals. Those with 5 years and above illness duration had a higher percentage of relapse (52.02%) as well as those with poor drug compliance (66.16%). The mean relapse age was 34.23 years. Educational status, employment status/social class, marital status, and age were socio-economic/clinical factors that associated strongly with relapse at p-value of 0.10. Patients with ≥ 5 and ≤ 3 years duration of illness were 1.17 times on the average more likely to have relapse than those with three or less than 3 years. Onset age for illness predicted 2.479 times more likelihood of relapse. Being employed and having more family support, as against being unskilled/unemployed and not having family support, reduce the likelihood of relapse by 1.110 times on the average. The study recommended policy formulation and implementation for protection against mental illness and mental healthcare provision and access; for tackling unemployment head-on; for improvement of the access to effective treatment of mental illness; and mass education, especially among unemployed, uneducated, singles, and under-35 years of age, to help reduce the high rate of relapse of mental illness in South-East Nigeria.

A comparative analysis of road and vehicle qualities as factors of road traffic carnage in Nigeria.

BACKGROUND AND OBJECTIVE: Carnage on roads is a growing concern in Nigeria. Over 27 persons, equivalent to more than 4 families, die daily from road traffic crashes. Two direct factors of a road crash are road quality and vehicle quality. To interrogate and compare both factors to road traffic accidents, the longitudinal study regressed secondary data on death tolls against road quality and vehicle quality. MATERIALS AND METHODS: Data on the estimated number of vehicles imported into Nigeria (1992-2021) served as the indicator of vehicle quality on Nigerian roads. The longitudinal study regressed secondary data on death tolls (2013-2019) against road quality (2006-2019) and vehicle quality (1992-2021). RESULTS: Results showed that road quality is degenerating as well as vehicle quality in Nigeria, resulting in increase in the number of road traffic crashes and the attendant death tolls. For every 1% decrease in road quality, death tolls from road traffic crashes in Nigeria increased by 0.00642% at 5% significance, and for every decrease in vehicle quality, death tolls from road traffic crashes in Nigeria increased by 0.327% at 5% significance. CONCLUSION: The study recommended increased advocacy on the sanctity of life and the need for all tiers of government to prioritize policy and implementation of improving the road quality and vehicle quality to reduce road traffic crashes and save lives on Nigerian roads.

Health effects of selected trace elements in hairdressing cosmetics on hairdressers in Enugu, Nigeria.

Could trace elements in hairdressing cosmetics prove carcinogenic to hairdressers, who use them regularly as raw materials in hairdressing business? The toxic effects of selected trace elements contained in hairdressing cosmetics on hairdressers were investigated by regressing the quality of life values for hairdressers with their blood/urine levels of the toxic metals A hundred subjects were randomly drawn from a cluster of hairdressers. Blood lead level, 17.47 ± 4.59 µg/dL, confirmed that the hairdressers were regularly exposed to lead. Mean blood mercury level, 25.06 ± 4.11 ng/dL, was above the normal blood mercury concentration of less than 10-20 ng/mL. Mean blood cadmium level, 3.64 ± 1.87 µg/dL, was within the normal range, < 5.0 µg/dL. Mean urine arsenic level, 96.16 ± 38.34 µg/L, was above normal range, ≤ 50 µg/dL, but within high normal range, > 50 to < 200 µg/dL. Blood nickel level, 0.49 ± 0.20 µg/dL, was above both the healthy range, 0.14-0.65 µg/dL, and the most reliable value of 0.2 µg/dL. Negative correlations existed between the quality of life and levels for lead (R = - .017), mercury (R = - .008), arsenic (R = - .072) and nickel (R = - .168), but there was positive correlation with cadmium level (R = .123). At 0.096, the probability value (p value) for nickel was significant at 10%. P value as insignificant at 1%, 5% and 10% for lead (0.868), mercury (0.940), cadmium (0.224) and arsenic (0.475). Therefore, Ni contained in hairdressing cosmetics might have carcinogenic effects that affected the quality of life of hairdressers, unlike other trace elements tested, namely, lead, mercury, cadmium and arsenic. Further research with the tumor markers assessment is recommended to confirm the carcinogenic effect of Ni.

Toxic effects of selected trace elements contained in make-ups on female university students in Nigeria.

Arsenic (As), cadmium (Cd), lead (Pb), mercury (Hg), beryllium (Be), nickel (Ni), selenium (Se), and thallium (Tl) are reportedly notorious toxic contents of make-ups, with potential to cause cancer and chronic kidney disease, warranting investigation on their toxic effects. One hundred female university students were randomly selected as consistent users of make-ups for upward of 3 years. The serum/urine levels of the 8 elements were regressed against the kidney functions (estimated glomerular rate, eGFR) of the subjects. At coefficient of - 0.009, As had insignificant (0.518) level. The coefficient for Cd was - .155 and insignificant (0.423). At coefficient of - 039, Pb level was insignificant (0.595). The coefficient, 0.061, for Hg was insignificant (0.462). At - 1.585, the coefficient of Be was insignificant (0.292). The coefficient for Ni, 1.384, was insignificant (0.354). At - .002, the coefficient of Se was insignificant (0.635). The coefficient, 0.039, for Tl was significant at 5% (0.015). This finding internally validated the mean serum Tl level, 201.4900 ± 20.63316 µg/L, which was much higher than the normal level of < 2 µg/L and within the toxic range of > 200 µg/L. A policy is needed to address the use of make-ups containing Tl.